Protein: NSL1
Kinetochore-associated protein NSL1

Gene: NSL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: Q12143

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000444 - MIS12/MIND type complex
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0000940 - outer kinetochore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

826924

DSN1
Kinetochore-associated protein DSN1

20

0

Small-scale

0.937

High

814097

MTW1
Kinetochore-associated protein MTW1

9

0

Small-scale

0.920

High

866078

NNF1
Kinetochore-associated protein NNF1

9

0

Small-scale

0.916

High

797910

CENPU
Inner kinetochore subunit AME1

8

0

Small-scale

0.714

High

919468

CENPQ
Inner kinetochore subunit OKP1

4

0

Small-scale

0.658

High

763756

CENPC
Inner kinetochore subunit MIF2

4

0

Small-scale

0.643

High

1084400

CENPI
Inner kinetochore subunit CTF3

3

0

Small-scale

0.622

High

527984

HSP72
Heat shock protein SSA2

2

2

Small-scale

0.611

High

917743

KNL1
Outer kinetochore KNL1 complex subunit SPC105

2

0

Small-scale

0.598

High

1038172

CENPP
Inner kinetochore subunit CTF19

2

0

High-throughput

0.588

High

807029

CENPN
Inner kinetochore subunit CHL4

2

0

Small-scale

0.585

High

525505

HSP71
Heat shock protein SSA1

2

2

Small-scale

0.571

High

817044

SPC25
Kinetochore protein SPC25

2

0

Small-scale

0.569

High

1046725

SPC24
Kinetochore protein SPC24

2

0

High-throughput

0.547

High

1084398

CENPH
Inner kinetochore subunit MCM16

2

0

Small-scale

0.547

High

574752

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.537

High

926720

MPS1
Serine/threonine-protein kinase MPS1

1

1

High-throughput

0.536

High

866215

CENPK
Inner kinetochore subunit MCM22

1

0

High-throughput

0.513

High

1084399

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.513

High

815608

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.480

High

864441

IKS1
Probable serine/threonine-protein kinase IKS1

1

0

High-throughput

0.480

High

676458

MAS5
Mitochondrial protein import protein MAS5

1

1

Small-scale

0.479

High

740234

RPN2
26S proteasome regulatory subunit RPN2

1

1

Small-scale

0.479

High

803717

RPN1
26S proteasome regulatory subunit RPN1

1

1

Small-scale

0.479

High

826110

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.460

High

779369

CENPA
Histone H3-like centromeric protein CSE4

1

0

Small-scale

0.458

High

917924

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

1064285

SGO1
Shugoshin

1

0

Small-scale

0.458

High

1084397

PSH1
RING finger protein PSH1

1

0

Small-scale

0.458

High

645782

HSP74
Heat shock protein SSA4

1

2

High-throughput

0.445

High

742649

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

804552

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

811250

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

671738

SCJ1
DnaJ-related protein SCJ1

1

1

Small-scale

0.437

High

738782

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

797133

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.426

High

843242

STB1
Protein STB1

1

0

High-throughput

0.426

High

1053952

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.426

High

1054004

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.426

High

1056411

CENPO
Inner kinetochore subunit MCM21

1

0

High-throughput

0.426

High

1084115

MDN1
Midasin

1

0

High-throughput

0.426

High

1084184

VIK1
Spindle pole body-associated protein VIK1

1

0

High-throughput

0.426

High

1046598

ZWINT
Outer kinetochore KNL1 complex subunit KRE28

1

0

High-throughput

0.391

High

793285

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

2

0

High-throughput

0.307

High

817573

SERA
D-3-phosphoglycerate dehydrogenase 1

1

0

High-throughput

0.282

High

678907

CSM1
Monopolin complex subunit CSM1

1

0

Small-scale

0.279

Low

808269

VPS41
Vacuolar protein sorting-associated protein 41

1

0

Small-scale

0.251

Low

395004

EF1A
Elongation factor 1-alpha

1

0

Small-scale

0.249

Low

626922

HSP60
Heat shock protein 60, mitochondrial

1

0

Small-scale

0.249

Low

1018342

TMA20
Translation machinery-associated protein 20

1

0

High-throughput

0.249

Low

1061328

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.249

Low

864070

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low

1035188

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

1053858

CIS1
Citrinin resistance protein, mitochondrial

1

0

High-throughput

0.238

Low

1064969

SOG2
Leucine-rich repeat-containing protein SOG2

1

0

High-throughput

0.238

Low

367825

ENO1
Enolase 1

1

0

High-throughput

0.232

Low

738276

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

0

High-throughput

0.232

Low

763865

SKI2
Antiviral helicase SKI2

1

0

High-throughput

0.232

Low

806249

SVP26
Protein SVP26

1

0

High-throughput

0.232

Low

824674

BNR1
BNI1-related protein 1

1

0

High-throughput

0.232

Low

1028044

ACAC
Acetyl-CoA carboxylase

1

0

High-throughput

0.232

Low

1033461

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.232

Low

1046758

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

1062778

YO075
Uncharacterized ABC transporter ATP-binding protein/permease YOL075C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025