Protein: ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating (EC 1.1.1.170) (C-3 sterol dehydrogenase ERG26) (C-4 decarboxylase ERG26) (Ergosterol biosynthetic protein 26)

Gene: ERG26
Organism: Saccharomyces cerevisiae S288C
Interactions: 50
UniProt ID: P53199

Gene Ontology (top 5):
GO:0000252 - C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
GO:0003854 - 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006696 - ergosterol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

767128

ERG28
Ergosterol biosynthetic protein 28

3

1

Small-scale

0.670

High

858725

ERG25
C-4 methylsterol oxidase ERG25

3

2

Small-scale

0.660

High

669540

ERG9
Squalene synthase ERG9

2

2

Small-scale

0.614

High

690385

ERG24
Delta(14)-sterol reductase ERG24

2

3

Small-scale

0.614

High

495853

CP51
Lanosterol 14-alpha demethylase CYP51

1

3

Small-scale

0.541

High

629484

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

3

Small-scale

0.541

High

688611

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

2

Small-scale

0.541

High

860071

TMEDA
Endoplasmic reticulum vesicle protein 25

1

4

High-throughput

0.541

High

860082

ERG27
3-keto-steroid reductase ERG27

1

2

Small-scale

0.541

High

544128

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.533

High

626469

ERG6
Sterol 24-C-methyltransferase ERG6

1

0

Small-scale

0.518

High

688581

ERG2
C-8 sterol isomerase ERG2

1

0

Small-scale

0.518

High

690789

ERG1
Squalene epoxidase ERG1

1

0

Small-scale

0.518

High

750809

ERG7
Lanosterol synthase ERG7

1

0

Small-scale

0.518

High

860077

ORM2
Protein ORM2

1

0

High-throughput

0.518

High

676229

XPO1
Exportin-1

1

1

High-throughput

0.489

High

860076

ERP1
Protein ERP1

1

3

High-throughput

0.457

High

366631

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.437

High

628293

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

664955

BMH1
Protein BMH1

1

3

High-throughput

0.437

High

745783

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

841410

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.437

High

860070

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

1

High-throughput

0.437

High

860073

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

High-throughput

0.437

High

860078

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

860079

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

860081

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

High-throughput

0.437

High

494521

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

769007

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

785121

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.407

High

744783

MCM7
DNA replication licensing factor MCM7

2

0

High-throughput

0.319

High

360969

TBB
Tubulin beta chain

1

0

High-throughput

0.279

Low

860080

MDN1
Midasin

1

0

High-throughput

0.279

Low

357332

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

407200

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

485779

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.249

Low

606077

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

662844

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

680880

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

730027

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

758007

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

762404

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

765009

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.249

Low

797492

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

820074

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

860072

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

860074

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.249

Low

860075

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

368255

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

424623

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024