Protein: EPHA3
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)

Gene: EPHA3
Organism: Homo sapiens
Interactions: 99
UniProt ID: P29320

Gene Ontology (top 5):
GO:0005003 - ephrin receptor activity
GO:0005004 - GPI-linked ephrin receptor activity
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

665382

EFNA5
Ephrin-A5

6

20

Small-scale

0.944

High

665399

EPHA7
Ephrin type-A receptor 7

4

19

Small-scale

0.899

High

354677

DRA
HLA class II histocompatibility antigen, DR alpha chain

2

11

High-throughput

0.789

High

665381

EFNB2
Ephrin-B2

2

20

Small-scale

0.778

High

665421

SRPK1
SRSF protein kinase 1

1

9

High-throughput

0.735

High

665419

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

2

19

High-throughput

0.726

High

665374

EPHB2
Ephrin type-B receptor 2

1

18

Small-scale

0.724

High

665142

EPHA2
Ephrin type-A receptor 2

1

19

High-throughput

0.715

High

665402

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

2

8

High-throughput

0.705

High

665386

TPTE
Putative tyrosine-protein phosphatase TPTE

1

9

High-throughput

0.698

High

665410

DUS18
Dual specificity protein phosphatase 18

1

20

High-throughput

0.698

High

665415

STYX
Serine/threonine/tyrosine-interacting protein

1

20

High-throughput

0.698

High

167480

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

11

High-throughput

0.691

High

665383

EPHA5
Ephrin type-A receptor 5

1

19

High-throughput

0.691

High

665385

EPHA4
Ephrin type-A receptor 4

1

18

High-throughput

0.691

High

337359

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.647

High

412036

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.647

High

522802

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.647

High

595975

EFNA1
Ephrin-A1

1

20

Small-scale

0.647

High

665379

EFNA3
Ephrin-A3

1

20

Small-scale

0.647

High

665380

EFNA4
Ephrin-A4

1

20

Small-scale

0.647

High

665390

EFNB1
Ephrin-B1

1

20

Small-scale

0.647

High

665384

EPHB4
Ephrin type-B receptor 4

1

18

High-throughput

0.646

High

665430

DUS21
Dual specificity protein phosphatase 21

1

20

High-throughput

0.625

High

383631

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

129209

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.618

High

277011

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.618

High

348528

RASN
GTPase NRas

1

20

High-throughput

0.618

High

349904

RASK
GTPase KRas

1

20

High-throughput

0.618

High

433602

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

530151

NCAM1
Neural cell adhesion molecule 1

1

6

Small-scale

0.618

High

655220

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

665377

MUC18
Cell surface glycoprotein MUC18

1

13

High-throughput

0.618

High

665378

CRK
Adapter molecule crk

1

20

Small-scale

0.618

High

665387

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

665388

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

6

High-throughput

0.618

High

665389

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

665392

DYST
Dystonin

1

8

High-throughput

0.618

High

665393

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

20

High-throughput

0.618

High

665398

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

665403

PDZ11
PDZ domain-containing protein 11

1

15

High-throughput

0.618

High

665406

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.618

High

665414

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.618

High

665420

ERBIN
Erbin

1

15

High-throughput

0.618

High

665432

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

12

High-throughput

0.618

High

665433

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.618

High

665435

WDR6
tRNA

1

13

High-throughput

0.618

High

665439

KDIS
Kinase D-interacting substrate of 220 kDa

1

8

High-throughput

0.618

High

665424

RNF5
E3 ubiquitin-protein ligase RNF5

1

5

Small-scale

0.561

High

665431

TM231
Transmembrane protein 231

2

1

High-throughput

0.558

High

665407

LRC49
Leucine-rich repeat-containing protein 49

1

20

High-throughput

0.553

High

149969

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

5

High-throughput

0.541

High

665418

RBM18
Probable RNA-binding protein 18

1

5

High-throughput

0.541

High

665427

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

8

High-throughput

0.541

High

300529

NFAT5
Nuclear factor of activated T-cells 5

1

4

High-throughput

0.536

High

665394

SLAF1
Signaling lymphocytic activation molecule

1

18

High-throughput

0.536

High

665401

CDC37
Hsp90 co-chaperone Cdc37

1

18

High-throughput

0.536

High

665413

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

2

High-throughput

0.536

High

665376

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

16

Small-scale

0.516

High

665416

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.515

High

386158

P53
Cellular tumor antigen p53

1

3

Small-scale

0.501

High

665441

FBX7
F-box only protein 7

1

3

High-throughput

0.501

High

428666

TRY1
Serine protease 1

1

6

High-throughput

0.500

High

654090

CALX
Calnexin

1

12

High-throughput

0.500

High

665425

F118B
Protein FAM118B

1

1

High-throughput

0.489

High

152259

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

17

Small-scale

0.479

High

159898

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.479

High

310517

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

11

High-throughput

0.479

High

431562

HS90A
Heat shock protein HSP 90-alpha

1

20

Small-scale

0.479

High

566936

CXA1
Gap junction alpha-1 protein

1

13

High-throughput

0.479

High

665375

MYH9
Myosin-9

1

6

Small-scale

0.479

High

665391

CLH1
Clathrin heavy chain 1

1

2

Small-scale

0.479

High

665396

DSG2
Desmoglein-2

1

20

High-throughput

0.479

High

665397

FLOT2
Flotillin-2

1

12

High-throughput

0.479

High

665400

AAAT
Neutral amino acid transporter B(0)

1

8

High-throughput

0.479

High

665405

F1711
Protein FAM171A1

1

10

High-throughput

0.479

High

665408

AHNK2
Protein AHNAK2

1

4

High-throughput

0.479

High

665412

VANG1
Vang-like protein 1

1

3

High-throughput

0.479

High

665423

CDCA3
Cell division cycle-associated protein 3

1

8

High-throughput

0.479

High

665426

RHG39
Rho GTPase-activating protein 39

1

9

High-throughput

0.479

High

665428

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

2

High-throughput

0.479

High

665434

JPH1
Junctophilin-1

1

8

High-throughput

0.479

High

665437

VAPA
Vesicle-associated membrane protein-associated protein A

1

11

High-throughput

0.479

High

665438

TRM7
tRNA

1

7

High-throughput

0.479

High

665440

NISCH
Nischarin

1

20

High-throughput

0.479

High

559568

H12
Histone H1.2

1

2

High-throughput

0.470

High

69720

FHAD1
Forkhead-associated domain-containing protein 1

1

6

High-throughput

0.457

High

520692

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

1

High-throughput

0.457

High

239797

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

11

High-throughput

0.445

High

665395

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

10

High-throughput

0.445

High

665422

RUFY1
RUN and FYVE domain-containing protein 1

1

14

Small-scale

0.445

High

68141

F1712
Protein FAM171A2

1

10

High-throughput

0.437

High

665417

CK052
Uncharacterized protein C11orf52

1

5

High-throughput

0.437

High

665429

GCP60
Golgi resident protein GCP60

1

9

High-throughput

0.437

High

665436

GGA3
ADP-ribosylation factor-binding protein GGA3

1

20

High-throughput

0.437

High

59909

MTMRB
Myotubularin-related protein 11

1

0

High-throughput

0.282

High

665404

MDH1B
Putative malate dehydrogenase 1B

1

0

High-throughput

0.261

Low

665409

CC116
Coiled-coil domain-containing protein 116

1

0

High-throughput

0.249

Low

665411

TET5D
Terminal nucleotidyltransferase 5D

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024