Protein: KMT2E
Inactive histone-lysine N-methyltransferase 2E (Inactive lysine N-methyltransferase 2E) (Myeloid/lymphoid or mixed-lineage leukemia protein 5)

Gene: KMT2E
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q8IZD2

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0002446 - neutrophil mediated immunity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1224162

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

20

Small-scale

0.647

High

997802

RBBP4
Histone-binding protein RBBP4

1

20

Small-scale

0.618

High

1052706

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

10

Small-scale

0.618

High

1224154

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

20

Small-scale

0.618

High

1224155

WDR12
Ribosome biogenesis protein WDR12

1

15

Small-scale

0.618

High

1224160

WDR6
tRNA

1

20

Small-scale

0.618

High

1224159

AT131
Endoplasmic reticulum transmembrane helix translocase

2

5

High-throughput

0.606

High

1224158

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

0

Small-scale

0.586

High

1121611

BOREA
Borealin

1

0

Small-scale

0.537

High

1041087

CUL1
Cullin-1

1

8

High-throughput

0.536

High

387079

P53
Cellular tumor antigen p53

1

6

Small-scale

0.534

High

327881

NCTR2
Natural cytotoxicity triggering receptor 2

1

2

Small-scale

0.534

High

206391

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.518

High

519034

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

414987

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.501

High

802654

CRK
Adapter molecule crk

1

8

High-throughput

0.501

High

125903

CDC7
Cell division cycle 7-related protein kinase

1

9

Small-scale

0.479

High

131469

IMA4
Importin subunit alpha-4

1

6

Small-scale

0.479

High

175031

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

11

Small-scale

0.479

High

199782

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

Small-scale

0.479

High

321917

RIGI
Antiviral innate immune response receptor RIG-I

1

12

Small-scale

0.479

High

486810

MYB
Transcriptional activator Myb

1

4

High-throughput

0.479

High

509054

TOP2A
DNA topoisomerase 2-alpha

1

4

Small-scale

0.479

High

575497

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

596785

CD11B
Cyclin-dependent kinase 11B

1

6

Small-scale

0.479

High

625511

CDK2
Cyclin-dependent kinase 2

1

4

Small-scale

0.479

High

627299

MCM3
DNA replication licensing factor MCM3

1

14

Small-scale

0.479

High

632811

TYY1
Transcriptional repressor protein YY1

1

8

Small-scale

0.479

High

848253

HCFC1
Host cell factor 1

1

11

Small-scale

0.479

High

941143

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1019565

ILF2
Interleukin enhancer-binding factor 2

1

5

Small-scale

0.479

High

1038522

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

1054427

RBM39
RNA-binding protein 39

1

11

Small-scale

0.479

High

1058243

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

5

Small-scale

0.479

High

1183937

DHX30
ATP-dependent RNA helicase DHX30

1

8

Small-scale

0.479

High

1191689

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

16

Small-scale

0.479

High

1224151

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

Small-scale

0.479

High

1224152

SIN3A
Paired amphipathic helix protein Sin3a

1

7

Small-scale

0.479

High

1224153

DDX50
ATP-dependent RNA helicase DDX50

1

9

Small-scale

0.479

High

1224157

ZN768
Zinc finger protein 768

1

3

Small-scale

0.479

High

1224163

VPS4A
Vacuolar protein sorting-associated protein 4A

1

2

Small-scale

0.479

High

1224164

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

Small-scale

0.479

High

1224165

TRAF6
TNF receptor-associated factor 6

1

13

Small-scale

0.479

High

1224156

DDX24
ATP-dependent RNA helicase DDX24

1

8

Small-scale

0.437

High

1224161

DDX18
ATP-dependent RNA helicase DDX18

1

8

Small-scale

0.437

High


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Last updated: 15 Jul 2024