Protein: TGT
Queuine tRNA-ribosyltransferase catalytic subunit 1 (EC 2.4.2.64) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)

Gene: TGT, QTRT1
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q9BXR0

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0006400 - tRNA modification
GO:0008479 - tRNA-guanosine(34) queuine transglycosylase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

127176

APBB1
Amyloid beta precursor protein binding family B member 1

3

1

High-throughput

0.667

High

532924

CH60
60 kDa heat shock protein, mitochondrial

3

1

High-throughput

0.667

High

1369627

APBB2
Amyloid beta precursor protein binding family B member 2

3

1

High-throughput

0.667

High

1417227

THUM1
THUMP domain-containing protein 1

3

2

High-throughput

0.667

High

1007602

PRAME
Melanoma antigen preferentially expressed in tumors

3

0

High-throughput

0.638

High

1417225

DPOE4
DNA polymerase epsilon subunit 4

2

0

High-throughput

0.585

High

537838

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.536

High

1051415

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.518

High

1139829

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.518

High

1272547

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.518

High

1395284

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

1417226

NUA4L
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2

1

0

High-throughput

0.518

High

249513

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

1099636

NOGG
Noggin

1

0

High-throughput

0.513

High

1414158

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1270977

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.480

High

589600

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

696413

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

1334870

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1417229

XPO7
Exportin-7

1

2

High-throughput

0.479

High

1226518

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.458

High

1417228

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

124959

GTPB1
GTP-binding protein 1

1

1

High-throughput

0.437

High

769082

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

942857

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.437

High

1255382

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1129121

PLSI
Plastin-1

3

0

High-throughput

0.347

High

1417230

CLC11
C-type lectin domain family 11 member A

3

0

High-throughput

0.347

High

423084

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.328

High

1105169

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

1408410

SH3G3
Endophilin-A3

1

0

High-throughput

0.282

High

675145

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.279

Low

789666

HPCL1
Hippocalcin-like protein 1

1

0

High-throughput

0.279

Low

1160926

PRSS8
Prostasin

1

0

High-throughput

0.279

Low

1218860

GP107
Protein GPR107

1

0

High-throughput

0.279

Low

1352084

TS1R2
Taste receptor type 1 member 2

1

0

High-throughput

0.279

Low

1417224

BORG4
Cdc42 effector protein 4

1

0

High-throughput

0.279

Low

975217

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025