Protein: OPALI
Opalin (Oligodendrocytic myelin paranodal and inner loop protein) (Transmembrane protein 10)

Gene: OPALI, OPALIN
Organism: Homo sapiens
Interactions: 222
UniProt ID: Q96PE5

Gene Ontology (top 5):
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0044291 - cell-cell contact zone
GO:0048713 - regulation of oligodendrocyte differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627395

AT2B1
Plasma membrane calcium-transporting ATPase 1

2

5

High-throughput

0.601

High

661317

AT2B4
Plasma membrane calcium-transporting ATPase 4

2

5

High-throughput

0.601

High

1023382

AT2C1
Calcium-transporting ATPase type 2C member 1

2

3

High-throughput

0.601

High

1399654

FLVC1
Choline/ethanolamine transporter FLVCR1

2

1

High-throughput

0.601

High

1399660

S4A7
Sodium bicarbonate cotransporter 3

2

1

High-throughput

0.601

High

878078

AGRE5
Adhesion G protein-coupled receptor E5

2

0

High-throughput

0.576

High

1316764

WDFY3
WD repeat and FYVE domain-containing protein 3

2

0

High-throughput

0.576

High

839495

PI4KA
Phosphatidylinositol 4-kinase alpha

2

2

High-throughput

0.552

High

317210

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

2

2

High-throughput

0.549

High

1204588

PIGG
GPI ethanolamine phosphate transferase 2, catalytic subunit

2

1

High-throughput

0.549

High

1399619

AT131
Endoplasmic reticulum transmembrane helix translocase

2

3

High-throughput

0.549

High

275913

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

1

High-throughput

0.536

High

336566

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.536

High

401323

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.536

High

411011

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

2

High-throughput

0.536

High

420036

B3A2
Anion exchange protein 2

1

1

High-throughput

0.536

High

463202

YES
Tyrosine-protein kinase Yes

1

1

High-throughput

0.536

High

522725

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

1

High-throughput

0.536

High

537739

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.536

High

552061

ADT1
ADP/ATP translocase 1

1

1

High-throughput

0.536

High

565686

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.536

High

603339

KPCA
Protein kinase C alpha type

1

1

High-throughput

0.536

High

658759

JAK1
Tyrosine-protein kinase JAK1

1

1

High-throughput

0.536

High

658922

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

1

High-throughput

0.536

High

690118

AVR2A
Activin receptor type-2A

1

3

High-throughput

0.536

High

720304

UFO
Tyrosine-protein kinase receptor UFO

1

1

High-throughput

0.536

High

761488

HS71L
Heat shock 70 kDa protein 1-like

1

1

High-throughput

0.536

High

787236

BMR1A
Bone morphogenetic protein receptor type-1A

1

3

High-throughput

0.536

High

787333

ACV1B
Activin receptor type-1B

1

3

High-throughput

0.536

High

839344

MTOR
Serine/threonine-protein kinase mTOR

1

6

High-throughput

0.536

High

912707

CTR2
Cationic amino acid transporter 2

1

2

High-throughput

0.536

High

944956

RAB38
Ras-related protein Rab-38

1

2

High-throughput

0.536

High

1032641

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

3

High-throughput

0.536

High

1048382

ACVR1
Activin receptor type-1

1

3

High-throughput

0.536

High

1051956

KPCD
Protein kinase C delta type

1

1

High-throughput

0.536

High

1063010

DDR1
Epithelial discoidin domain-containing receptor 1

1

1

High-throughput

0.536

High

1109490

ATR
Serine/threonine-protein kinase ATR

1

3

High-throughput

0.536

High

1145062

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.536

High

1162306

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

4

High-throughput

0.536

High

1177621

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

1

High-throughput

0.536

High

1243041

PKN3
Serine/threonine-protein kinase N3

1

2

High-throughput

0.536

High

1259435

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.536

High

1323753

S39AB
Zinc transporter ZIP11

1

1

High-throughput

0.536

High

1361289

CTR3
Cationic amino acid transporter 3

1

2

High-throughput

0.536

High

1369918

MRP2
ATP-binding cassette sub-family C member 2

1

1

High-throughput

0.536

High

1399598

S39A3
Zinc transporter ZIP3

1

1

High-throughput

0.536

High

1399599

EFC4B
EF-hand calcium-binding domain-containing protein 4B

1

2

High-throughput

0.536

High

1399602

KPCD2
Serine/threonine-protein kinase D2

1

1

High-throughput

0.536

High

1399624

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

2

High-throughput

0.536

High

1399637

CPNE7
Copine-7

1

1

High-throughput

0.536

High

1399658

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

2

High-throughput

0.536

High

161243

EI24
Etoposide-induced protein 2.4 homolog

1

0

High-throughput

0.513

High

184496

SURF4
Surfeit locus protein 4

1

0

High-throughput

0.513

High

194846

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.513

High

291122

UTP20
Small subunit processome component 20 homolog

1

0

High-throughput

0.513

High

528778

MGST1
Microsomal glutathione S-transferase 1

1

0

High-throughput

0.513

High

609778

LEG3
Galectin-3

1

0

High-throughput

0.513

High

637940

NF1
Neurofibromin

1

0

High-throughput

0.513

High

845110

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

890877

TSC2
Tuberin

1

0

High-throughput

0.513

High

897596

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.513

High

902216

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.513

High

908044

VAMP7
Vesicle-associated membrane protein 7

1

0

High-throughput

0.513

High

1006938

KC1G2
Casein kinase I isoform gamma-2

1

0

High-throughput

0.513

High

1101184

CLN3
Battenin

1

0

High-throughput

0.513

High

1122036

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.513

High

1130715

DIP2A
Disco-interacting protein 2 homolog A

1

0

High-throughput

0.513

High

1193125

PKHN1
Pleckstrin homology domain-containing family N member 1

1

0

High-throughput

0.513

High

1212204

MPP7
MAGUK p55 subfamily member 7

1

0

High-throughput

0.513

High

1245118

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.513

High

1273965

DYM
Dymeclin

1

0

High-throughput

0.513

High

1286706

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.513

High

1325076

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

1346759

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.513

High

1349681

CIP2A
Protein CIP2A

1

0

High-throughput

0.513

High

1356597

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.513

High

1399592

XPO6
Exportin-6

1

0

High-throughput

0.513

High

1399593

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.513

High

1399595

NIBA2
Protein Niban 2

1

0

High-throughput

0.513

High

1399600

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.513

High

1399614

DOCK5
Dedicator of cytokinesis protein 5

1

0

High-throughput

0.513

High

1399621

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.513

High

1399633

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

1399634

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.513

High

1399640

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.513

High

1399643

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.513

High

1399647

S27A6
Long-chain fatty acid transport protein 6

1

0

High-throughput

0.513

High

164628

TNPO2
Transportin-2

1

2

High-throughput

0.489

High

174056

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

4

High-throughput

0.489

High

189256

IPO8
Importin-8

1

3

High-throughput

0.489

High

225386

ERD23
ER lumen protein-retaining receptor 3

1

2

High-throughput

0.489

High

269042

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

2

High-throughput

0.489

High

273223

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

3

High-throughput

0.489

High

318155

IPO13
Importin-13

1

4

High-throughput

0.489

High

521415

ARAF
Serine/threonine-protein kinase A-Raf

1

2

High-throughput

0.489

High

552356

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

665004

ERD21
ER lumen protein-retaining receptor 1

1

2

High-throughput

0.489

High

755508

ERD22
ER lumen protein-retaining receptor 2

1

2

High-throughput

0.489

High

934145

XPO2
Exportin-2

1

3

High-throughput

0.489

High

967168

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

1

High-throughput

0.489

High

996814

TBA1B
Tubulin alpha-1B chain

1

1

High-throughput

0.489

High

1008291

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

High-throughput

0.489

High

1043169

TAP1
Antigen peptide transporter 1

1

2

High-throughput

0.489

High

1102228

ATM
Serine-protein kinase ATM

1

3

High-throughput

0.489

High

1198389

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

2

High-throughput

0.489

High

1200274

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

1

High-throughput

0.489

High

1207006

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.489

High

1219326

ECM29
Proteasome adapter and scaffold protein ECM29

1

2

High-throughput

0.489

High

1225727

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

2

High-throughput

0.489

High

1242088

TTC27
Tetratricopeptide repeat protein 27

1

1

High-throughput

0.489

High

1277516

MON2
Protein MON2 homolog

1

2

High-throughput

0.489

High

1288648

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

2

High-throughput

0.489

High

1349165

S2540
Mitochondrial glutathione transporter SLC25A40

1

3

High-throughput

0.489

High

1365731

GCN1
Stalled ribosome sensor GCN1

1

2

High-throughput

0.489

High

1381678

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.489

High

1399604

XPO4
Exportin-4

1

3

High-throughput

0.489

High

1399615

AT133
Polyamine-transporting ATPase 13A3

1

5

High-throughput

0.489

High

1399617

XPO5
Exportin-5

1

5

High-throughput

0.489

High

1399618

TPC
Mitochondrial thiamine pyrophosphate carrier

1

2

High-throughput

0.489

High

1399623

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

2

High-throughput

0.489

High

1399626

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

2

High-throughput

0.489

High

1399628

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

4

High-throughput

0.489

High

1399641

IPO11
Importin-11

1

3

High-throughput

0.489

High

1399642

XPO7
Exportin-7

1

5

High-throughput

0.489

High

1399652

TNPO3
Transportin-3

1

4

High-throughput

0.489

High

1399655

ORNT1
Mitochondrial ornithine transporter 1

1

3

High-throughput

0.489

High

1399656

MTCH2
Mitochondrial carrier homolog 2

1

3

High-throughput

0.489

High

1399657

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

2

High-throughput

0.489

High

932116

EPHA4
Ephrin type-A receptor 4

1

1

High-throughput

0.457

High

229902

ATP9B
Probable phospholipid-transporting ATPase IIB

1

1

High-throughput

0.445

High

722584

CTR1
High affinity cationic amino acid transporter 1

1

2

High-throughput

0.445

High

753839

MRP1
Multidrug resistance-associated protein 1

1

1

High-throughput

0.445

High

1399653

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

0

Small-scale

0.438

High

506645

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.437

High

1195683

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

1

High-throughput

0.437

High

615227

IL1RA
Interleukin-1 receptor antagonist protein

1

0

High-throughput

0.426

High

1399620

IL1AP
Interleukin-1 receptor accessory protein

1

0

High-throughput

0.426

High

1399639

GTR6
Solute carrier family 2, facilitated glucose transporter member 6

1

0

High-throughput

0.426

High

85392

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

1307351

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

1

High-throughput

0.407

High

173739

BTAF1
TATA-binding protein-associated factor 172

2

0

High-throughput

0.313

High

1251551

THADA
tRNA

2

0

High-throughput

0.313

High

1260314

INT8
Integrator complex subunit 8

2

0

High-throughput

0.313

High

1336546

MROH1
Maestro heat-like repeat-containing protein family member 1

2

0

High-throughput

0.313

High

1347142

WDR48
WD repeat-containing protein 48

2

0

High-throughput

0.313

High

1399610

GHITM
Growth hormone-inducible transmembrane protein

2

0

High-throughput

0.313

High

1399625

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

2

0

High-throughput

0.313

High

1399627

MDN1
Midasin

2

0

High-throughput

0.313

High

1399635

ERAP1
Endoplasmic reticulum aminopeptidase 1

2

0

High-throughput

0.313

High

1399648

MAN1
Inner nuclear membrane protein Man1

2

0

High-throughput

0.313

High

71356

F1712
Protein FAM171A2

1

0

High-throughput

0.279

Low

301644

WFS1
Wolframin

1

0

High-throughput

0.279

Low

317910

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.279

Low

322755

RHBT3
Rho-related BTB domain-containing protein 3

1

0

High-throughput

0.279

Low

331791

MTMR5
Myotubularin-related protein 5

1

0

High-throughput

0.279

Low

337803

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.279

Low

397755

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

0

High-throughput

0.279

Low

789949

FDFT
Squalene synthase

1

0

High-throughput

0.279

Low

841234

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.279

Low

1065823

SLFN5
Schlafen family member 5

1

0

High-throughput

0.279

Low

1103841

TARB1
tRNA

1

0

High-throughput

0.279

Low

1121592

URB2
Unhealthy ribosome biogenesis protein 2 homolog

1

0

High-throughput

0.279

Low

1147555

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.279

Low

1151053

PCH2
Pachytene checkpoint protein 2 homolog

1

0

High-throughput

0.279

Low

1164035

SIA4B
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

1

0

High-throughput

0.279

Low

1179673

D19L1
Protein C-mannosyl-transferase DPY19L1

1

0

High-throughput

0.279

Low

1191940

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1212723

TMTC4
Protein O-mannosyl-transferase TMTC4

1

0

High-throughput

0.279

Low

1216016

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.279

Low

1220527

MIC13
MICOS complex subunit MIC13

1

0

High-throughput

0.279

Low

1224767

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.279

Low

1230757

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

1243324

INT5
Integrator complex subunit 5

1

0

High-throughput

0.279

Low

1251306

HACD2
Very-long-chain

1

0

High-throughput

0.279

Low

1280072

FRMD5
FERM domain-containing protein 5

1

0

High-throughput

0.279

Low

1280663

PKHH3
Pleckstrin homology domain-containing family H member 3

1

0

High-throughput

0.279

Low

1291724

RTTN
Rotatin

1

0

High-throughput

0.279

Low

1293737

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.279

Low

1322629

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.279

Low

1323831

INT1
Integrator complex subunit 1

1

0

High-throughput

0.279

Low

1329641

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.279

Low

1361085

MYO3B
Myosin-IIIb

1

0

High-throughput

0.279

Low

1361672

ELYS
Protein ELYS

1

0

High-throughput

0.279

Low

1365885

NU205
Nuclear pore complex protein Nup205

1

0

High-throughput

0.279

Low

1389562

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

1392152

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1392780

P121A
Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.279

Low

1394922

VPS50
Syndetin

1

0

High-throughput

0.279

Low

1398778

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

0

High-throughput

0.279

Low

1399594

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.279

Low

1399596

SMAD5
Mothers against decapentaplegic homolog 5

1

0

High-throughput

0.279

Low

1399601

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.279

Low

1399603

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.279

Low

1399605

DERL2
Derlin-2

1

0

High-throughput

0.279

Low

1399606

TM39B
Transmembrane protein 39B

1

0

High-throughput

0.279

Low

1399607

INT2
Integrator complex subunit 2

1

0

High-throughput

0.279

Low

1399608

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1399609

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.279

Low

1399611

PIGM
GPI alpha-1,4-mannosyltransferase I, catalytic subunit

1

0

High-throughput

0.279

Low

1399612

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

1399613

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1399616

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

0

High-throughput

0.279

Low

1399622

AAAS
Aladin

1

0

High-throughput

0.279

Low

1399629

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low

1399630

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.279

Low

1399631

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

High-throughput

0.279

Low

1399632

T161A
Transmembrane protein 161A

1

0

High-throughput

0.279

Low

1399636

COX16
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial

1

0

High-throughput

0.279

Low

1399638

GCP4
Gamma-tubulin complex component 4

1

0

High-throughput

0.279

Low

1399644

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.279

Low

1399645

DOLK
Dolichol kinase

1

0

High-throughput

0.279

Low

1399646

PLAP
Phospholipase A-2-activating protein

1

0

High-throughput

0.279

Low

1399649

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.279

Low

1399650

DOP1B
Protein DOP1B

1

0

High-throughput

0.279

Low

1399651

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.279

Low

1399659

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.279

Low

1399661

AP1M2
AP-1 complex subunit mu-2

1

0

High-throughput

0.279

Low

955892

GMFB
Glia maturation factor beta

1

0

High-throughput

0.232

Low

999398

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.232

Low

1219173

LYPL1
Lysophospholipase-like protein 1

1

0

High-throughput

0.232

Low

1273225

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

0

High-throughput

0.232

Low

1399597

DHB14
L-fucose dehydrogenase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025