Protein: ITBP1
Integrin beta-1-binding protein 1 (Integrin cytoplasmic domain-associated protein 1) (ICAP-1)

Gene: ITBP1, ITGB1BP1
Organism: Homo sapiens
Interactions: 32
UniProt ID: O14713

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0002043 - blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0005092 - GDP-dissociation inhibitor activity
GO:0005178 - integrin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

139111

KRIT1
Krev interaction trapped protein 1

7

0

Small-scale

0.923

High

161555

ITB1
Integrin beta-1

4

0

Small-scale

0.665

High

161574

CCM2
Cerebral cavernous malformations 2 protein

4

0

Small-scale

0.661

High

161567

RHOH
Rho-related GTP-binding protein RhoH

2

1

High-throughput

0.606

High

161557

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

2

0

High-throughput

0.580

High

161558

NDKB
Nucleoside diphosphate kinase B

1

0

Small-scale

0.561

High

161577

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

1

Small-scale

0.561

High

161568

FIGL1
Fidgetin-like protein 1

1

0

High-throughput

0.549

High

129908

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.529

High

161564

LRP2
Low-density lipoprotein receptor-related protein 2

1

2

Small-scale

0.527

High

161565

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

2

Small-scale

0.527

High

161552

GSDME
Gasdermin-E

1

0

High-throughput

0.518

High

161560

UTRN
Utrophin

1

0

High-throughput

0.518

High

161571

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.518

High

161573

SMO
Protein smoothened

1

0

High-throughput

0.518

High

161554

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

161576

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

1

Small-scale

0.501

High

161553

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

161559

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

161561

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

161563

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.486

High

161578

FAF1
FAS-associated factor 1

1

0

High-throughput

0.486

High

161566

LRP8
Low-density lipoprotein receptor-related protein 8

1

2

Small-scale

0.481

High

126362

RHOD
Rho-related GTP-binding protein RhoD

1

1

High-throughput

0.479

High

161550

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

161551

XPO1
Exportin-1

1

0

High-throughput

0.458

High

161562

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.458

High

161570

SNIP1
Smad nuclear-interacting protein 1

1

0

Small-scale

0.458

High

161572

TANK
TRAF family member-associated NF-kappa-B activator

1

0

Small-scale

0.458

High

161556

S10A9
Protein S100-A9

1

0

Small-scale

0.438

High

161575

TLRN1
Talin rod domain-containing protein 1

2

0

High-throughput

0.313

High

161569

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025