Protein: GPBAR
G-protein coupled bile acid receptor 1 (G-protein coupled receptor GPCR19) (hGPCR19) (Membrane-type receptor for bile acids) (M-BAR) (hBG37) (BG37)

Gene: GPBAR, GPBAR1
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q8TDU6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0038182 - G protein-coupled bile acid receptor activity
GO:0038184 - adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

787321

ACV1B
Activin receptor type-1B

1

0

High-throughput

0.656

High

1351736

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

2

High-throughput

0.536

High

133546

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

170521

RAB7L
Ras-related protein Rab-7L1

1

0

High-throughput

0.513

High

178563

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

0

High-throughput

0.513

High

565676

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.513

High

943099

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

1333746

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

1351738

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.513

High

1351739

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

1351741

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

0

High-throughput

0.513

High

1351744

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

1351742

AT131
Endoplasmic reticulum transmembrane helix translocase

1

1

High-throughput

0.489

High

1351743

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

2

High-throughput

0.489

High

674259

BRD2
Bromodomain-containing protein 2

1

0

High-throughput

0.458

High

801427

HSPA9
Stress-70 protein, mitochondrial

1

0

Small-scale

0.458

High

165627

SCAM3
Secretory carrier-associated membrane protein 3

1

0

High-throughput

0.279

Low

337780

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.279

Low

800223

VKGC
Vitamin K-dependent gamma-carboxylase

1

0

High-throughput

0.279

Low

944407

SYJ2B
Synaptojanin-2-binding protein

1

0

High-throughput

0.279

Low

963584

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.279

Low

1211783

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1349160

S2540
Mitochondrial glutathione transporter SLC25A40

1

0

High-throughput

0.279

Low

1351735

TM9S4
Transmembrane 9 superfamily member 4

1

0

High-throughput

0.279

Low

1351737

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

0

High-throughput

0.279

Low

1351740

SFXN3
Sideroflexin-3

1

0

High-throughput

0.279

Low

1351745

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.279

Low

1351746

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.279

Low

506629

GPHRB
Golgi pH regulator B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025