Protein: CD28
T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28)

Gene: CD28
Organism: Homo sapiens
Interactions: 20
UniProt ID: P10747

Gene Ontology (top 5):
GO:0001772 - immunological synapse
GO:0001819 - positive regulation of cytokine production
GO:0002020 - protease binding
GO:0002863 - positive regulation of inflammatory response to antigenic stimulus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

499345

CD80
T-lymphocyte activation antigen CD80

5

7

Small-scale

0.927

High

499346

CD86
T-lymphocyte activation antigen CD86

2

7

Small-scale

0.768

High

499343

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

19

6

Small-scale

0.764

High

499350

GRB2
Growth factor receptor-bound protein 2

5

6

Small-scale

0.709

High

275166

GRAP2
GRB2-related adapter protein 2

3

5

Small-scale

0.687

High

499348

EFNB2
Ephrin-B2

1

1

High-throughput

0.536

High

499351

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.536

High

449160

LEG1
Galectin-1

1

0

High-throughput

0.513

High

499349

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

499352

HBA
Hemoglobin subunit alpha

1

0

High-throughput

0.513

High

499356

O56B4
Olfactory receptor 56B4

1

0

High-throughput

0.493

High

129179

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

11

Small-scale

0.479

High

499342

VAV
Proto-oncogene vav

1

1

Small-scale

0.479

High

499344

1433S
14-3-3 protein sigma

1

2

High-throughput

0.479

High

499347

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

Small-scale

0.458

High

499357

DOK1
Docking protein 1

1

0

Small-scale

0.458

High

499353

KPCT
Protein kinase C theta type

1

0

Small-scale

0.426

High

304911

DUS14
Dual specificity protein phosphatase 14

1

0

Small-scale

0.299

High

499354

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.279

Low

499355

TM192
Transmembrane protein 192

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024