Protein: UBP50
Ubiquitin carboxyl-terminal hydrolase 50 (EC 3.4.19.12) (Ubiquitin-specific peptidase 50)

Gene: UBP50, USP50
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q70EL3

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1258248

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

9

High-throughput

0.691

High

1258251

ASC
Apoptosis-associated speck-like protein containing a CARD

2

3

Small-scale

0.624

High

468526

HS90B
Heat shock protein HSP 90-beta

1

9

Small-scale

0.552

High

134066

IPO5
Importin-5

1

1

High-throughput

0.536

High

701853

ABCD3
ATP-binding cassette sub-family D member 3

1

1

High-throughput

0.536

High

906089

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

2

High-throughput

0.536

High

959191

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.536

High

984174

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

High-throughput

0.536

High

1258240

TBA1A
Tubulin alpha-1A chain

1

5

High-throughput

0.536

High

1258241

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.536

High

1258253

SRPRB
Signal recognition particle receptor subunit beta

1

2

High-throughput

0.536

High

539073

UMPS
Uridine 5'-monophosphate synthase

1

0

High-throughput

0.513

High

541105

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1247862

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.513

High

1258245

NU205
Nuclear pore complex protein Nup205

1

0

High-throughput

0.513

High

728307

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

Small-scale

0.501

High

548525

MPRI
Cation-independent mannose-6-phosphate receptor

1

5

High-throughput

0.489

High

774450

BASI
Basigin

1

2

High-throughput

0.489

High

1058481

CKAP4
Cytoskeleton-associated protein 4

1

10

High-throughput

0.489

High

1258244

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

1

High-throughput

0.489

High

1258249

LUC7L
Putative RNA-binding protein Luc7-like 1

1

1

High-throughput

0.489

High

1258250

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

1

High-throughput

0.489

High

461631

HS90A
Heat shock protein HSP 90-alpha

1

8

Small-scale

0.481

High

537388

HSP7C
Heat shock cognate 71 kDa protein

1

3

Small-scale

0.479

High

558220

XRCC6
X-ray repair cross-complementing protein 6

1

2

Small-scale

0.479

High

887437

CEBPD
CCAAT/enhancer-binding protein delta

1

3

Small-scale

0.479

High

1258242

STING
Stimulator of interferon genes protein

1

4

Small-scale

0.479

High

1258246

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

0

Small-scale

0.458

High

1258254

ZHX2
Zinc fingers and homeoboxes protein 2

1

0

Small-scale

0.458

High

1258243

MIRO1
Mitochondrial Rho GTPase 1

1

5

High-throughput

0.437

High

1258247

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.301

High

1153266

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.279

Low

1258252

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.279

Low

895254

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025