Protein: MIRO1
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)

Gene: MIRO1, RHOT1
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q8IXI2

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005509 - calcium ion binding
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1312177

MIRO2
Mitochondrial Rho GTPase 2

4

18

High-throughput

0.892

High

134083

IPO5
Importin-5

2

9

High-throughput

0.811

High

1312330

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

2

20

Small-scale

0.776

High

242224

PRKN
E3 ubiquitin-protein ligase parkin

16

18

Small-scale

0.762

High

1312341

TRAK1
Trafficking kinesin-binding protein 1

5

20

Small-scale

0.700

High

783621

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

20

High-throughput

0.691

High

1104437

ILK
Scaffold protein ILK

1

19

High-throughput

0.691

High

905615

IRAK1
Interleukin-1 receptor-associated kinase 1

2

0

High-throughput

0.671

High

244858

TRAK2
Trafficking kinesin-binding protein 2

3

20

High-throughput

0.667

High

828397

PEX19
Peroxisomal biogenesis factor 19

3

2

High-throughput

0.667

High

66448

ASB14
Ankyrin repeat and SOCS box protein 14

1

20

High-throughput

0.618

High

154847

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

9

High-throughput

0.618

High

412229

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

1312337

EXOC1
Exocyst complex component 1

1

1

High-throughput

0.618

High

1312322

HUMMR
Protein MGARP

2

1

Small-scale

0.611

High

391338

FRIL
Ferritin light chain

2

0

High-throughput

0.576

High

1209365

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

13

High-throughput

0.575

High

1312345

MTCH2
Mitochondrial carrier homolog 2

2

12

High-throughput

0.571

High

1236175

NAA16
N-alpha-acetyltransferase 16, NatA auxiliary subunit

1

10

High-throughput

0.553

High

1254553

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

1312319

CDK20
Cyclin-dependent kinase 20

1

10

Small-scale

0.553

High

1312333

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

1312334

ANLN
Anillin

1

13

High-throughput

0.553

High

1312338

XPO7
Exportin-7

1

11

High-throughput

0.553

High

182644

GP182
G-protein coupled receptor 182

1

17

High-throughput

0.536

High

634777

GRAH
Granzyme H

1

5

High-throughput

0.536

High

1093539

TRDN
Triadin

1

18

High-throughput

0.536

High

1310211

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

3

High-throughput

0.536

High

1312321

PPTC7
Protein phosphatase PTC7 homolog

1

2

High-throughput

0.536

High

1312326

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

20

High-throughput

0.536

High

1227025

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.514

High

165982

FFAR1
Free fatty acid receptor 1

1

18

High-throughput

0.489

High

321296

ERLN2
Erlin-2

1

20

Small-scale

0.489

High

1312342

KLK5
Kallikrein-5

1

8

High-throughput

0.489

High

1312343

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.489

High

106236

APRIO
Alternative prion protein

1

5

High-throughput

0.479

High

275057

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

2

High-throughput

0.479

High

488819

FURIN
Furin

1

3

High-throughput

0.479

High

530053

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.479

High

564032

CFTR
Cystic fibrosis transmembrane conductance regulator

1

20

High-throughput

0.479

High

766681

PHB1
Prohibitin 1

1

20

High-throughput

0.479

High

774484

BASI
Basigin

1

20

High-throughput

0.479

High

939939

TPTE
Putative tyrosine-protein phosphatase TPTE

1

9

High-throughput

0.479

High

1280329

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

20

High-throughput

0.479

High

1312325

AKAP1
A-kinase anchor protein 1, mitochondrial

1

11

High-throughput

0.479

High

1312336

TMPS4
Transmembrane protease serine 4

1

7

High-throughput

0.479

High

1312340

AMFR
E3 ubiquitin-protein ligase AMFR

1

4

Small-scale

0.479

High

244173

KIF5C
Kinesin heavy chain isoform 5C

1

4

Small-scale

0.470

High

1250092

MIC27
MICOS complex subunit MIC27

1

0

High-throughput

0.458

High

1312335

DISC1
Disrupted in schizophrenia 1 protein

1

0

Small-scale

0.458

High

1312323

SP7
Transcription factor Sp7

1

6

High-throughput

0.457

High

1147634

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

5

High-throughput

0.445

High

1309387

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

11

High-throughput

0.445

High

1312324

S39A7
Zinc transporter SLC39A7

1

20

High-throughput

0.445

High

164385

NRP1
Neuropilin-1

1

17

High-throughput

0.437

High

174550

TRI66
Tripartite motif-containing protein 66

1

6

High-throughput

0.437

High

293987

CD123
Translation initiation factor eIF2 assembly protein

1

8

High-throughput

0.437

High

587730

DESP
Desmoplakin

1

20

High-throughput

0.437

High

589110

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.437

High

831036

CCNF
Cyclin-F

1

3

High-throughput

0.437

High

872509

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.437

High

1100102

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.437

High

1133521

NFIX
Nuclear factor 1 X-type

1

11

High-throughput

0.437

High

1141767

EEA1
Early endosome antigen 1

1

15

High-throughput

0.437

High

1258243

UBP50
Ubiquitin carboxyl-terminal hydrolase 50

1

5

High-throughput

0.437

High

1286824

TM11B
Transmembrane protease serine 11B

1

7

High-throughput

0.437

High

1312318

SMC5
Structural maintenance of chromosomes protein 5

1

5

High-throughput

0.437

High

1312320

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

3

Small-scale

0.437

High

1312327

GCC1
GRIP and coiled-coil domain-containing protein 1

1

20

High-throughput

0.437

High

1312328

DDRGK
DDRGK domain-containing protein 1

1

7

High-throughput

0.437

High

1312329

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

20

High-throughput

0.437

High

1312332

SPRTN
DNA-dependent metalloprotease SPRTN

1

4

High-throughput

0.437

High

1312339

CCNL1
Cyclin-L1

1

1

High-throughput

0.437

High

1312344

TACC3
Transforming acidic coiled-coil-containing protein 3

1

20

High-throughput

0.437

High

58861

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

12

High-throughput

0.407

High

143455

E2F3
Transcription factor E2F3

1

3

Small-scale

0.407

High

255115

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

1197818

S39AC
Zinc transporter ZIP12

1

20

High-throughput

0.407

High

1312331

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025