Protein: CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) (Succinyltransferase CPT1A) (EC 2.3.1.-)

Gene: CPT1A
Organism: Homo sapiens
Interactions: 143
UniProt ID: P50416

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001676 - long-chain fatty acid metabolic process
GO:0004095 - carnitine O-palmitoyltransferase activity
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

844993

EAA3
Excitatory amino acid transporter 3

2

1

High-throughput

0.601

High

241109

PRKN
E3 ubiquitin-protein ligase parkin

2

1

Small-scale

0.584

High

895233

RAC1
Ras-related C3 botulinum toxin substrate 1

2

3

High-throughput

0.571

High

895235

KPCZ
Protein kinase C zeta type

2

1

High-throughput

0.571

High

895236

PAK1
Serine/threonine-protein kinase PAK 1

2

1

High-throughput

0.571

High

895238

CLN3
Battenin

2

0

Small-scale

0.559

High

895303

HDAC6
Protein deacetylase HDAC6

2

1

High-throughput

0.558

High

622425

ELK1
ETS domain-containing protein Elk-1

2

0

High-throughput

0.547

High

125008

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

173884

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.536

High

182494

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.536

High

380621

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

1

High-throughput

0.536

High

538548

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.536

High

565581

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

895291

S22A4
Solute carrier family 22 member 4

1

3

High-throughput

0.536

High

895300

S39A9
Zinc transporter ZIP9

1

7

High-throughput

0.536

High

895304

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.533

High

835614

KPCI
Protein kinase C iota type

2

1

High-throughput

0.521

High

131152

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.518

High

532460

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.515

High

470928

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

520787

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

724006

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.513

High

895228

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.513

High

895243

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

895256

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.513

High

895258

INLR1
Interferon lambda receptor 1

1

0

High-throughput

0.513

High

895265

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

895275

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

895281

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

895294

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

895305

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.513

High

507689

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

438875

CD1A
T-cell surface glycoprotein CD1a

1

1

High-throughput

0.489

High

575647

GPIX
Platelet glycoprotein IX

1

1

High-throughput

0.489

High

895279

HDA11
Histone deacetylase 11

1

2

High-throughput

0.489

High

895308

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

895277

ESR2
Estrogen receptor beta

1

1

High-throughput

0.484

High

652473

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

3

High-throughput

0.481

High

137679

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.479

High

274993

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

276083

NIPS2
Protein NipSnap homolog 2

1

3

Small-scale

0.479

High

342797

HERC2
E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.479

High

358644

LDHA
L-lactate dehydrogenase A chain

1

1

Small-scale

0.479

High

411590

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

895230

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

895242

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

534796

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.460

High

562788

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.460

High

178214

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

377463

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

400492

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

413423

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

418017

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

463407

LYN
Tyrosine-protein kinase Lyn

1

0

Small-scale

0.458

High

772366

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

861067

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

895227

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

895232

H4
Histone H4

1

0

High-throughput

0.458

High

895239

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

895240

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

895246

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

895257

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

895261

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

895263

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

895267

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

895278

OPTN
Optineurin

1

0

High-throughput

0.458

High

895301

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

47907

S12A8
Solute carrier family 12 member 8

1

3

High-throughput

0.445

High

538739

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

1

High-throughput

0.445

High

653197

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

722417

CTR1
High affinity cationic amino acid transporter 1

1

2

High-throughput

0.445

High

844911

EAA2
Excitatory amino acid transporter 2

1

1

High-throughput

0.445

High

895241

S39AE
Metal cation symporter ZIP14

1

8

High-throughput

0.445

High

895262

S39AB
Zinc transporter ZIP11

1

9

High-throughput

0.445

High

895269

ZNT7
Zinc transporter 7

1

1

High-throughput

0.445

High

895276

S39A7
Zinc transporter SLC39A7

1

8

High-throughput

0.445

High

895310

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.445

High

181981

UBD
Ubiquitin D

1

1

High-throughput

0.437

High

244425

ZN862
Zinc finger protein 862

1

1

High-throughput

0.437

High

466157

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.437

High

482371

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.437

High

694943

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

895229

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.437

High

895231

RHOA
Transforming protein RhoA

1

3

High-throughput

0.437

High

895245

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.437

High

895253

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

895255

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

895259

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.437

High

895296

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.437

High

117218

SIM22
Small integral membrane protein 22

1

0

Small-scale

0.426

High

421735

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.426

High

880819

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.426

High

895260

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.426

High

895282

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.426

High

895307

FLVC1
Choline/ethanolamine transporter FLVCR1

1

0

High-throughput

0.426

High

303220

S22A5
Organic cation/carnitine transporter 2

1

3

High-throughput

0.407

High

895244

S39AC
Zinc transporter ZIP12

1

8

High-throughput

0.407

High

895247

S39A4
Zinc transporter ZIP4

1

8

High-throughput

0.407

High

895268

SPX3
Sugar phosphate exchanger 3

1

1

High-throughput

0.407

High

895270

S7A14
Solute carrier family 7 member 14

1

2

High-throughput

0.407

High

895271

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

1

High-throughput

0.407

High

895285

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

1

High-throughput

0.407

High

895286

S39A3
Zinc transporter ZIP3

1

8

High-throughput

0.407

High

895290

S39A8
Metal cation symporter ZIP8

1

8

High-throughput

0.407

High

895297

S39A2
Zinc transporter ZIP2

1

8

High-throughput

0.407

High

615152

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

2

0

High-throughput

0.328

High

895252

TBCD9
TBC1 domain family member 9

2

0

High-throughput

0.328

High

895273

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.282

High

260743

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

618374

TSN8
Tetraspanin-8

1

0

High-throughput

0.279

Low

655748

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.279

Low

848461

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.279

Low

895234

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.279

Low

895237

KLRD1
Natural killer cells antigen CD94

1

0

High-throughput

0.279

Low

895250

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

895274

ITLN1
Intelectin-1

1

0

High-throughput

0.279

Low

895280

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

895288

TMM59
Transmembrane protein 59

1

0

High-throughput

0.279

Low

895293

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

895306

PCDGM
Protocadherin gamma-C5

1

0

High-throughput

0.279

Low

895309

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

895298

NPDC1
Neural proliferation differentiation and control protein 1

1

0

High-throughput

0.251

Low

208480

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

217968

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

293384

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

353111

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

895248

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

895249

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

895254

UBP50
Ubiquitin carboxyl-terminal hydrolase 50

1

0

Small-scale

0.249

Low

895272

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

895283

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

895284

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.249

Low

895287

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

895289

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.249

Low

895292

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

895295

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

0

High-throughput

0.249

Low

895299

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

895302

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

379495

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low

895251

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

895264

LAT4
Large neutral amino acids transporter small subunit 4

1

0

High-throughput

0.232

Low

895266

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025