Protein: OSBL3
Oxysterol-binding protein-related protein 3 (ORP-3) (OSBP-related protein 3)

Gene: OSBL3, OSBPL3
Organism: Homo sapiens
Interactions: 105
UniProt ID: Q9H4L5

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006699 - bile acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

905111

1433G
14-3-3 protein gamma

6

20

High-throughput

0.736

High

310813

VAPB
Vesicle-associated membrane protein-associated protein B/C

6

20

Small-scale

0.732

High

683711

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.716

High

982497

1433F
14-3-3 protein eta

5

20

High-throughput

0.716

High

1331232

VAPA
Vesicle-associated membrane protein-associated protein A

4

20

High-throughput

0.704

High

160779

AURKA
Aurora kinase A

4

4

High-throughput

0.694

High

1318023

OSBL7
Oxysterol-binding protein-related protein 7

1

12

High-throughput

0.691

High

1234608

ARRD1
Arrestin domain-containing protein 1

3

1

High-throughput

0.667

High

1331230

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

3

1

High-throughput

0.667

High

647275

1433T
14-3-3 protein theta

3

20

High-throughput

0.662

High

927525

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.662

High

1157179

TTI2
TELO2-interacting protein 2

3

0

High-throughput

0.634

High

50244

HACL2
2-hydroxyacyl-CoA lyase 2

2

2

High-throughput

0.628

High

305629

ZFPL1
Zinc finger protein-like 1

2

3

High-throughput

0.628

High

1023797

TRAF1
TNF receptor-associated factor 1

2

1

High-throughput

0.628

High

1288031

HDA11
Histone deacetylase 11

2

2

High-throughput

0.628

High

1295281

JPH4
Junctophilin-4

2

2

High-throughput

0.628

High

1331231

NOP53
Ribosome biogenesis protein NOP53

2

1

High-throughput

0.628

High

910026

1433E
14-3-3 protein epsilon

2

2

High-throughput

0.611

High

129049

PLK4
Serine/threonine-protein kinase PLK4

2

4

High-throughput

0.606

High

585932

WT1
Wilms tumor protein

2

1

High-throughput

0.606

High

891321

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

10

High-throughput

0.606

High

1203943

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

2

1

High-throughput

0.606

High

1328028

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

2

10

High-throughput

0.606

High

217052

PRIC3
Prickle planar cell polarity protein 3

2

0

High-throughput

0.602

High

1291374

CPNE2
Copine-2

2

0

High-throughput

0.602

High

915974

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

202525

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

0

High-throughput

0.580

High

923216

RL11
Large ribosomal subunit protein uL5

2

0

High-throughput

0.580

High

984027

ZBT16
Zinc finger and BTB domain-containing protein 16

2

0

High-throughput

0.580

High

1046955

BYST
Bystin

2

0

High-throughput

0.580

High

1286286

SYTL4
Synaptotagmin-like protein 4

2

0

High-throughput

0.580

High

1331236

T3JAM
TRAF3-interacting JNK-activating modulator

2

0

High-throughput

0.580

High

1331233

ARP3B
Actin-related protein 3B

2

1

High-throughput

0.574

High

1075180

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.553

High

1237642

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

1

High-throughput

0.553

High

1252476

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.553

High

1255349

STK35
Serine/threonine-protein kinase 35

2

2

High-throughput

0.553

High

1028525

KLRD1
Natural killer cells antigen CD94

1

3

High-throughput

0.536

High

1070631

RNPS1
RNA-binding protein with serine-rich domain 1

1

1

High-throughput

0.536

High

1216836

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.536

High

1232526

PHTF2
Protein PHTF2

1

1

High-throughput

0.536

High

1272770

FGF13
Fibroblast growth factor 13

1

1

High-throughput

0.536

High

1284807

EFMT3
EEF1A lysine methyltransferase 3

1

2

High-throughput

0.536

High

1317692

PITM3
Membrane-associated phosphatidylinositol transfer protein 3

1

1

High-throughput

0.536

High

1331227

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

684325

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

416700

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

1048425

NID2
Nidogen-2

1

0

High-throughput

0.513

High

1057391

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.513

High

1069298

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

0

High-throughput

0.513

High

1166489

ELAP1
Endosome/lysosome-associated apoptosis and autophagy regulator 1

1

0

High-throughput

0.513

High

1233954

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.513

High

358895

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.501

High

950874

ERH
Enhancer of rudimentary homolog

1

1

High-throughput

0.489

High

1272815

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.489

High

1331235

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.489

High

350552

RASK
GTPase KRas

1

13

High-throughput

0.479

High

374866

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

436507

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

545617

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

573909

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

738045

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

High-throughput

0.479

High

892595

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

900901

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

925615

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

951338

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

999093

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.479

High

1064150

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1066695

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

1281938

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.479

High

1326145

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

10

Small-scale

0.479

High

1330915

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1331226

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

1331238

CBY1
Protein chibby homolog 1

1

1

High-throughput

0.479

High

1331239

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

Small-scale

0.479

High

1331240

KCTD3
BTB/POZ domain-containing protein KCTD3

1

1

High-throughput

0.479

High

123001

MEN1
Menin

1

0

High-throughput

0.458

High

591097

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

917917

H4
Histone H4

1

0

High-throughput

0.458

High

1036534

MTM1
Myotubularin

1

0

High-throughput

0.458

High

1129588

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

240185

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

1331234

TBK1
Serine/threonine-protein kinase TBK1

1

1

Small-scale

0.445

High

652243

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

1171708

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1331229

OTULL
Inactive ubiquitin thioesterase OTULINL

1

6

High-throughput

0.437

High

1328208

TSYL1
Testis-specific Y-encoded-like protein 1

2

0

High-throughput

0.328

High

997330

ACSM1
Acyl-coenzyme A synthetase ACSM1, mitochondrial

2

0

High-throughput

0.316

High

1107945

F161A
Protein FAM161A

2

0

High-throughput

0.316

High

1133864

ZN648
Zinc finger protein 648

2

0

High-throughput

0.316

High

1169391

ZN497
Zinc finger protein 497

2

0

High-throughput

0.316

High

1290757

MCRS1
Microspherule protein 1

2

0

High-throughput

0.316

High

1298271

ZNF48
Zinc finger protein 48

2

0

High-throughput

0.316

High

1305377

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.316

High

1331237

ZN835
Zinc finger protein 835

2

0

High-throughput

0.316

High

471653

TFPT
TCF3 fusion partner

1

0

High-throughput

0.279

Low

1259614

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.279

Low

1283729

EMID1
EMI domain-containing protein 1

1

0

High-throughput

0.279

Low

101180

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

577473

PACA
Pituitary adenylate cyclase-activating polypeptide

1

0

High-throughput

0.249

Low

1202459

HOOK3
Protein Hook homolog 3

1

0

High-throughput

0.249

Low

1239323

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1256398

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

1331228

SP110
Sp110 nuclear body protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024