Protein: YPEL3
Protein yippee-like 3

Gene: YPEL3
Organism: Homo sapiens
Interactions: 128
UniProt ID: P61236

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0046872 - metal ion binding
GO:2000774 - positive regulation of cellular senescence

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

959461

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.710

High

930666

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

High-throughput

0.589

High

959472

ZYX
Zyxin

2

3

High-throughput

0.584

High

959514

FXL20
F-box/LRR-repeat protein 20

2

3

High-throughput

0.574

High

959546

FBXL2
F-box/LRR-repeat protein 2

2

3

High-throughput

0.574

High

783694

ZNF76
Zinc finger protein 76

1

1

High-throughput

0.555

High

959471

ZIC1
Zinc finger protein ZIC 1

1

1

High-throughput

0.555

High

959476

LONF1
LON peptidase N-terminal domain and RING finger protein 1

1

1

High-throughput

0.555

High

959466

FHL3
Four and a half LIM domains protein 3

2

2

High-throughput

0.533

High

291772

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.519

High

959496

ZN765
Zinc finger protein 765

1

0

High-throughput

0.519

High

959501

ZN441
Zinc finger protein 441

1

0

High-throughput

0.519

High

959521

TSSK3
Testis-specific serine/threonine-protein kinase 3

1

0

High-throughput

0.519

High

959522

SRPK1
SRSF protein kinase 1

1

3

High-throughput

0.514

High

161706

APAF
Apoptotic protease-activating factor 1

1

1

High-throughput

0.489

High

681777

RBTN2
Rhombotin-2

1

1

High-throughput

0.481

High

959469

TRIP6
Thyroid receptor-interacting protein 6

1

1

High-throughput

0.481

High

288294

GCM2
Chorion-specific transcription factor GCMb

1

0

High-throughput

0.460

High

297949

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.460

High

505542

ATX1L
Ataxin-1-like

1

0

High-throughput

0.460

High

511017

LIMS4
LIM and senescent cell antigen-like-containing domain protein 4

1

0

High-throughput

0.460

High

959459

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.460

High

959485

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

1

0

High-throughput

0.460

High

959503

HDAC7
Histone deacetylase 7

1

0

High-throughput

0.460

High

959520

TGM7
Protein-glutamine gamma-glutamyltransferase Z

1

0

High-throughput

0.460

High

959535

DMRT3
Doublesex- and mab-3-related transcription factor 3

1

0

High-throughput

0.460

High

959540

AIRIM
AFG2-interacting ribosome maturation factor

1

0

High-throughput

0.460

High

220232

FRS3
Fibroblast growth factor receptor substrate 3

1

1

High-throughput

0.439

High

330104

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.439

High

437459

CRBA1
Beta-crystallin A3 [Cleaved into: Beta-crystallin A3, isoform A1, Delta4 form; Beta-crystallin A3, isoform A1, Delta7 form; Beta-crystallin A3, isoform A1, Delta8 form]

1

1

High-throughput

0.439

High

733117

OTX1
Homeobox protein OTX1

1

1

High-throughput

0.439

High

922349

CRBA2
Beta-crystallin A2

1

1

High-throughput

0.439

High

933816

GEM
GTP-binding protein GEM

1

1

High-throughput

0.439

High

959463

TLE5
TLE family member 5

1

1

High-throughput

0.439

High

959468

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.439

High

959473

HSPB2
Heat shock protein beta-2

1

2

High-throughput

0.439

High

959481

KR151
Keratin-associated protein 15-1

1

1

High-throughput

0.439

High

959483

KR132
Keratin-associated protein 13-2

1

1

High-throughput

0.439

High

959484

FND3B
Fibronectin type III domain-containing protein 3B

1

1

High-throughput

0.439

High

959489

FHL5
Four and a half LIM domains protein 5

1

2

High-throughput

0.439

High

959493

MORN3
MORN repeat-containing protein 3

1

1

High-throughput

0.439

High

959494

DOK6
Docking protein 6

1

2

High-throughput

0.439

High

959495

LARP4
La-related protein 4

1

1

High-throughput

0.439

High

959499

TRI73
Tripartite motif-containing protein 73

1

1

High-throughput

0.439

High

959502

MYOZ3
Myozenin-3

1

1

High-throughput

0.439

High

959505

SHC3
SHC-transforming protein 3

1

1

High-throughput

0.439

High

959506

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

2

High-throughput

0.439

High

959510

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

High-throughput

0.439

High

959511

TET5B
Terminal nucleotidyltransferase 5B

1

1

High-throughput

0.439

High

959515

TET5A
Terminal nucleotidyltransferase 5A

1

1

High-throughput

0.439

High

959516

HEXI2
Protein HEXIM2

1

1

High-throughput

0.439

High

959518

TOX2
TOX high mobility group box family member 2

1

1

High-throughput

0.439

High

959527

KRA33
Keratin-associated protein 3-3

1

1

High-throughput

0.439

High

959528

KRA31
Keratin-associated protein 3-1

1

1

High-throughput

0.439

High

959529

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.439

High

959532

SH24A
SH2 domain-containing protein 4A

1

2

High-throughput

0.439

High

959533

MYOZ1
Myozenin-1

1

1

High-throughput

0.439

High

943750

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

0

High-throughput

0.282

High

873381

LSS
Lanosterol synthase

1

0

High-throughput

0.279

Low

959464

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.279

Low

959467

RIN1
Ras and Rab interactor 1

1

0

High-throughput

0.279

Low

959470

NAB2
NGFI-A-binding protein 2

1

0

High-throughput

0.279

Low

959482

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

0

High-throughput

0.279

Low

959523

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

0

High-throughput

0.279

Low

959538

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

421841

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

50050

KR231
Keratin-associated protein 23-1

1

0

High-throughput

0.251

Low

50288

ODAM
Odontogenic ameloblast-associated protein

1

0

High-throughput

0.251

Low

50323

F168B
Myelin-associated neurite-outgrowth inhibitor

1

0

High-throughput

0.251

Low

70168

CRTP1
Cysteine-rich tail protein 1

1

0

High-throughput

0.251

Low

71101

VGLL3
Transcription cofactor vestigial-like protein 3

1

0

High-throughput

0.251

Low

74115

VWC2L
von Willebrand factor C domain-containing protein 2-like

1

0

High-throughput

0.251

Low

169492

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

High-throughput

0.251

Low

180266

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.251

Low

221029

HAIR
Lysine-specific demethylase hairless

1

0

High-throughput

0.251

Low

224959

TLX3
T-cell leukemia homeobox protein 3

1

0

High-throughput

0.251

Low

225557

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

0

High-throughput

0.251

Low

295976

TPC6A
Trafficking protein particle complex subunit 6A

1

0

High-throughput

0.251

Low

351432

TBX6
T-box transcription factor TBX6

1

0

High-throughput

0.251

Low

681317

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.251

Low

694323

CO8A1
Collagen alpha-1(VIII) chain

1

0

High-throughput

0.251

Low

702912

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.251

Low

704434

GRAN
Grancalcin

1

0

High-throughput

0.251

Low

729206

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

0

High-throughput

0.251

Low

829056

RFC5
Replication factor C subunit 5

1

0

High-throughput

0.251

Low

885210

HXA1
Homeobox protein Hox-A1

1

0

High-throughput

0.251

Low

937458

CDN2D
Cyclin-dependent kinase 4 inhibitor D

1

0

High-throughput

0.251

Low

959460

PITX1
Pituitary homeobox 1

1

0

High-throughput

0.251

Low

959462

PR20A
Proline-rich protein 20A

1

0

High-throughput

0.251

Low

959465

MKRN3
E3 ubiquitin-protein ligase makorin-3

1

0

High-throughput

0.251

Low

959474

OBF1
POU domain class 2-associating factor 1

1

0

High-throughput

0.251

Low

959475

NRF1
Nuclear respiratory factor 1

1

0

High-throughput

0.251

Low

959477

DOK7
Protein Dok-7

1

0

High-throughput

0.251

Low

959478

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.251

Low

959479

KLH38
Kelch-like protein 38

1

0

High-throughput

0.251

Low

959480

KRA62
Keratin-associated protein 6-2

1

0

High-throughput

0.251

Low

959486

ACTMP
Actin maturation protease

1

0

High-throughput

0.251

Low

959487

CJ055
Uncharacterized protein C10orf55

1

0

High-throughput

0.251

Low

959488

INT11
Integrator complex subunit 11

1

0

High-throughput

0.251

Low

959490

TASO2
Protein TASOR 2

1

0

High-throughput

0.251

Low

959491

SPRY7
SPRY domain-containing protein 7

1

0

High-throughput

0.251

Low

959492

NB5R2
NADH-cytochrome b5 reductase 2

1

0

High-throughput

0.251

Low

959497

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.251

Low

959498

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.251

Low

959504

UBTD2
Ubiquitin domain-containing protein 2

1

0

High-throughput

0.251

Low

959507

TSC1
Hamartin

1

0

High-throughput

0.251

Low

959508

OSTF1
Osteoclast-stimulating factor 1

1

0

High-throughput

0.251

Low

959509

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.251

Low

959512

T53I1
Tumor protein p53-inducible nuclear protein 1

1

0

High-throughput

0.251

Low

959513

EID2B
EP300-interacting inhibitor of differentiation 2B

1

0

High-throughput

0.251

Low

959517

AP4AT
AP-4 complex accessory subunit Tepsin

1

0

High-throughput

0.251

Low

959519

GUCD1
Protein GUCD1

1

0

High-throughput

0.251

Low

959524

MDFI
MyoD family inhibitor

1

0

High-throughput

0.251

Low

959525

SPAG8
Sperm-associated antigen 8

1

0

High-throughput

0.251

Low

959526

CDCA4
Cell division cycle-associated protein 4

1

0

High-throughput

0.251

Low

959530

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.251

Low

959531

ARMC7
Armadillo repeat-containing protein 7

1

0

High-throughput

0.251

Low

959534

CABP2
Calcium-binding protein 2

1

0

High-throughput

0.251

Low

959536

PLS4
Phospholipid scramblase 4

1

0

High-throughput

0.251

Low

959537

FGF21
Fibroblast growth factor 21

1

0

High-throughput

0.251

Low

959539

FANCL
E3 ubiquitin-protein ligase FANCL

1

0

High-throughput

0.251

Low

959541

PRR13
Proline-rich protein 13

1

0

High-throughput

0.251

Low

959542

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.251

Low

959543

SPG21
Maspardin

1

0

High-throughput

0.251

Low

959544

TRI10
Tripartite motif-containing protein 10

1

0

High-throughput

0.251

Low

959545

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.251

Low

959547

TPC2L
Trafficking protein particle complex subunit 2-like protein

1

0

High-throughput

0.251

Low

959500

PA24D
Cytosolic phospholipase A2 delta

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025