Protein: PAPP1
Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A)

Gene: PAPP1, PAPPA
Organism: Homo sapiens
Interactions: 13
UniProt ID: Q13219

Gene Ontology (top 5):
GO:0004222 - metalloendopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0007166 - cell surface receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

532943

PRG2
Bone marrow proteoglycan

3

16

Small-scale

0.662

High

341374

PLMN
Plasminogen

1

15

Small-scale

0.647

High

950163

SMAD3
Mothers against decapentaplegic homolog 3

1

10

High-throughput

0.508

High

856887

STC1
Stanniocalcin-1

1

1

Small-scale

0.501

High

1028134

CBP
CREB-binding protein

1

6

Small-scale

0.481

High

1028131

PLEC
Plectin

1

3

High-throughput

0.470

High

171392

SMAD9
Mothers against decapentaplegic homolog 9

1

10

High-throughput

0.464

High

521349

SKIL
Ski-like protein

1

1

High-throughput

0.464

High

1028132

SMAD2
Mothers against decapentaplegic homolog 2

1

10

High-throughput

0.464

High

353666

IGHG1
Immunoglobulin heavy constant gamma 1

1

6

High-throughput

0.445

High

353933

IGHM
Immunoglobulin heavy constant mu

1

5

High-throughput

0.445

High

1028133

MCAF1
Activating transcription factor 7-interacting protein 1

1

4

High-throughput

0.417

High

555445

H2AX
Histone H2AX

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024