Protein: NUFP1
FMR1-interacting protein NUFIP1 (Nuclear FMR1-interacting protein 1) (Nuclear FMRP-interacting protein 1)

Gene: NUFP1, NUFIP1
Organism: Homo sapiens
Interactions: 145
UniProt ID: Q9UHK0

Gene Ontology (top 5):
GO:0000492 - box C/D snoRNP assembly
GO:0001650 - fibrillar center
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

938418

NH2L1
NHP2-like protein 1

4

1

Small-scale

0.882

High

1151332

ZNHI3
Zinc finger HIT domain-containing protein 3

9

1

Small-scale

0.756

High

1459990

RUVB1
RuvB-like 1

4

2

Small-scale

0.696

High

135727

DNM1L
Dynamin-1-like protein

3

2

High-throughput

0.667

High

138534

BIN1
Myc box-dependent-interacting protein 1

3

1

High-throughput

0.667

High

530529

TAU
Microtubule-associated protein tau

3

1

High-throughput

0.667

High

630446

RAB3A
Ras-related protein Rab-3A

3

1

High-throughput

0.667

High

1050722

DYN1
Dynamin-1

3

2

High-throughput

0.667

High

1110314

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

3

1

High-throughput

0.667

High

1409538

DPYL5
Dihydropyrimidinase-related protein 5

3

4

High-throughput

0.667

High

1448884

RAB6B
Ras-related protein Rab-6B

3

1

High-throughput

0.667

High

1459988

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

3

1

High-throughput

0.667

High

1459989

RUVB2
RuvB-like 2

3

2

Small-scale

0.660

High

1459991

NOP58
Nucleolar protein 58

3

2

Small-scale

0.657

High

960360

STX1B
Syntaxin-1B

3

1

High-throughput

0.656

High

133813

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

3

0

High-throughput

0.638

High

469566

SYPH
Synaptophysin

3

0

High-throughput

0.638

High

595631

H15
Histone H1.5

3

0

High-throughput

0.638

High

605535

SYN1
Synapsin-1

3

0

High-throughput

0.638

High

639177

SYT1
Synaptotagmin-1

3

0

High-throughput

0.638

High

651145

CALB2
Calretinin

3

0

High-throughput

0.638

High

963475

STXB1
Syntaxin-binding protein 1

3

0

High-throughput

0.638

High

1030708

ANK2
Ankyrin-2

3

0

High-throughput

0.638

High

1038374

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

3

0

High-throughput

0.638

High

1408065

H2B1L
Histone H2B type 1-L

3

0

High-throughput

0.638

High

1409871

RBM4B
RNA-binding protein 4B

3

0

High-throughput

0.638

High

1420596

TRIM2
Tripartite motif-containing protein 2

3

0

High-throughput

0.638

High

1453892

H2AW
Core histone macro-H2A.2

3

0

High-throughput

0.638

High

1057022

FMR1
Fragile X messenger ribonucleoprotein 1

2

1

Small-scale

0.633

High

1451210

BCD1
Box C/D snoRNA protein 1

3

0

Small-scale

0.628

High

791807

SYUA
Alpha-synuclein

2

1

High-throughput

0.611

High

176889

DCLK1
Serine/threonine-protein kinase DCLK1

3

2

High-throughput

0.609

High

221301

DCX
Neuronal migration protein doublecortin

3

1

High-throughput

0.609

High

482649

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

3

3

High-throughput

0.609

High

536360

MTAP2
Microtubule-associated protein 2

3

2

High-throughput

0.609

High

564859

NCAM1
Neural cell adhesion molecule 1

3

2

High-throughput

0.609

High

618489

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

3

3

High-throughput

0.609

High

731940

L1CAM
Neural cell adhesion molecule L1

3

1

High-throughput

0.609

High

906944

GPM6A
Neuronal membrane glycoprotein M6-a

3

2

High-throughput

0.609

High

948089

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

3

1

High-throughput

0.609

High

956621

RAB5B
Ras-related protein Rab-5B

3

1

High-throughput

0.609

High

962919

NCALD
Neurocalcin-delta

3

4

High-throughput

0.609

High

979428

VISL1
Visinin-like protein 1

3

4

High-throughput

0.609

High

1014871

HPCA
Neuron-specific calcium-binding protein hippocalcin

3

4

High-throughput

0.609

High

1088168

CNTN1
Contactin-1

3

1

High-throughput

0.609

High

1123239

DPYL1
Dihydropyrimidinase-related protein 1

3

4

High-throughput

0.609

High

1123282

DPYL3
Dihydropyrimidinase-related protein 3

3

4

High-throughput

0.609

High

1156366

SYUB
Beta-synuclein

3

1

High-throughput

0.609

High

1158720

DPYL2
Dihydropyrimidinase-related protein 2

3

4

High-throughput

0.609

High

1335399

CAMKV
CaM kinase-like vesicle-associated protein

3

3

High-throughput

0.609

High

1430775

SNAB
Beta-soluble NSF attachment protein

3

1

High-throughput

0.609

High

1454105

NTRI
Neurotrimin

3

1

High-throughput

0.609

High

1459984

HPCL4
Hippocalcin-like protein 4

3

4

High-throughput

0.609

High

989929

CANB1
Calcineurin subunit B type 1

2

0

High-throughput

0.602

High

1230916

Z324B
Zinc finger protein 324B

2

0

High-throughput

0.602

High

1429107

NXF2
Nuclear RNA export factor 2

2

0

High-throughput

0.602

High

1107530

GPM6B
Neuronal membrane glycoprotein M6-b

3

2

High-throughput

0.599

High

1159655

STX1A
Syntaxin-1A

3

1

High-throughput

0.599

High

599137

CBPE
Carboxypeptidase E

2

0

High-throughput

0.585

High

937603

CAD13
Cadherin-13

2

0

High-throughput

0.585

High

96789

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

322338

GLSK
Glutaminase kidney isoform, mitochondrial

2

1

High-throughput

0.558

High

630659

RAB3B
Ras-related protein Rab-3B

2

1

High-throughput

0.558

High

883069

AMPH
Amphiphysin

2

1

High-throughput

0.558

High

893541

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

2

3

High-throughput

0.558

High

968668

NCS1
Neuronal calcium sensor 1

2

4

High-throughput

0.558

High

999702

HBA
Hemoglobin subunit alpha

2

1

High-throughput

0.558

High

799552

BRCA1
Breast cancer type 1 susceptibility protein

1

0

Small-scale

0.549

High

923646

TTC3
E3 ubiquitin-protein ligase TTC3

1

1

High-throughput

0.541

High

251671

CCNT1
Cyclin-T1

1

0

Small-scale

0.537

High

324057

CSTN1
Calsyntenin-1

1

0

High-throughput

0.513

High

339002

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.513

High

686509

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

855249

NOP2
28S rRNA

1

0

High-throughput

0.513

High

1148822

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

0

High-throughput

0.513

High

1151227

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

1219067

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.513

High

1348988

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.513

High

1446782

SSF1
Suppressor of SWI4 1 homolog

1

0

High-throughput

0.513

High

1360310

GEMI6
Gem-associated protein 6

1

0

Small-scale

0.504

High

1459950

DDX20
Probable ATP-dependent RNA helicase DDX20

1

0

Small-scale

0.504

High

243478

GBG7

1

1

High-throughput

0.489

High

1407055

SNAG
Gamma-soluble NSF attachment protein

1

2

High-throughput

0.489

High

167135

GEMI2
Gem-associated protein 2

1

0

Small-scale

0.480

High

186102

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

1159342

TAF9
Transcription initiation factor TFIID subunit 9

1

0

Small-scale

0.480

High

1405744

KLF6
Krueppel-like factor 6

1

0

Small-scale

0.480

High

141157

NOP56
Nucleolar protein 56

1

2

Small-scale

0.479

High

1359946

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

2

Small-scale

0.479

High

1368665

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

1459985

PRP19
Pre-mRNA-processing factor 19

1

1

High-throughput

0.479

High

944586

GEMI4
Gem-associated protein 4

1

0

Small-scale

0.460

High

173512

XPO1
Exportin-1

1

0

High-throughput

0.458

High

342356

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

891861

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.458

High

898019

CDK9
Cyclin-dependent kinase 9

1

0

Small-scale

0.458

High

990841

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

996036

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

0

High-throughput

0.458

High

1045879

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1160609

SMN
Survival motor neuron protein

1

0

Small-scale

0.458

High

1367520

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1371984

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.458

High

1387618

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1393803

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1459981

NUFP1
FMR1-interacting protein NUFIP1

1

0

Small-scale

0.458

High

1212388

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

155882

DPYL4
Dihydropyrimidinase-related protein 4

1

4

High-throughput

0.437

High

380780

HBD
Hemoglobin subunit delta

1

1

High-throughput

0.437

High

716060

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

3

High-throughput

0.437

High

1325213

CADM2
Cell adhesion molecule 2

1

3

High-throughput

0.437

High

1459987

DYN3
Dynamin-3

1

2

High-throughput

0.437

High

69991

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

85176

B7Z613
Glycoprotein M6B

1

2

High-throughput

0.407

High

229885

EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3

3

0

High-throughput

0.347

High

252794

AP180
Clathrin coat assembly protein AP180

3

0

High-throughput

0.347

High

633942

ATP4A
Potassium-transporting ATPase alpha chain 1

3

0

High-throughput

0.347

High

774177

ADDB
Beta-adducin

3

0

High-throughput

0.347

High

838513

GRIA2
Glutamate receptor 2

3

0

High-throughput

0.347

High

954418

SNP25
Synaptosomal-associated protein 25

3

0

High-throughput

0.347

High

1032673

AT2B2
Plasma membrane calcium-transporting ATPase 2

3

0

High-throughput

0.347

High

1421281

SRCN1
SRC kinase signaling inhibitor 1

3

0

High-throughput

0.347

High

1432285

S12A5
Solute carrier family 12 member 5

3

0

High-throughput

0.347

High

1433647

E41L1
Band 4.1-like protein 1

3

0

High-throughput

0.347

High

1459982

NDRG4
Protein NDRG4

3

0

High-throughput

0.347

High

725563

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

2

0

High-throughput

0.328

High

1008653

MAP1A
Microtubule-associated protein 1A

2

0

High-throughput

0.328

High

1459986

MARE3
Microtubule-associated protein RP/EB family member 3

2

0

High-throughput

0.328

High

64583

MP3B2
Microtubule-associated protein 1 light chain 3 beta 2

2

0

High-throughput

0.318

High

269709

PLXA2
Plexin-A2

2

0

High-throughput

0.318

High

847455

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

2

0

High-throughput

0.318

High

958044

RAB14
Ras-related protein Rab-14

2

0

High-throughput

0.318

High

1051884

EF1A2
Elongation factor 1-alpha 2

2

0

High-throughput

0.318

High

1416307

SFXN3
Sideroflexin-3

2

0

High-throughput

0.318

High

1450083

CYRIB
CYFIP-related Rac1 interactor B

2

0

High-throughput

0.318

High

637116

VATC1
V-type proton ATPase subunit C 1

1

0

High-throughput

0.279

Low

1010198

GABT
4-aminobutyrate aminotransferase, mitochondrial

1

0

High-throughput

0.279

Low

1208341

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1219250

CHIC1
Cysteine-rich hydrophobic domain-containing protein 1

1

0

High-throughput

0.279

Low

1459674

SEPT3
Neuronal-specific septin-3

1

0

High-throughput

0.279

Low

106806

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

989395

VAMP2
Vesicle-associated membrane protein 2

1

0

High-throughput

0.249

Low

1346730

SCAM5
Secretory carrier-associated membrane protein 5

1

0

High-throughput

0.249

Low

1459983

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

294758

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025