Protein: PGAM2
Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M)

Gene: PGAM2
Organism: Homo sapiens
Interactions: 74
UniProt ID: P15259

Gene Ontology (top 5):
GO:0004082 - bisphosphoglycerate mutase activity
GO:0004619 - phosphoglycerate mutase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006094 - gluconeogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

582069

PGAM1
Phosphoglycerate mutase 1

7

14

High-throughput

0.960

High

459830

PMGE
Bisphosphoglycerate mutase

5

14

High-throughput

0.926

High

582104

PGAM4
Probable phosphoglycerate mutase 4

5

14

High-throughput

0.922

High

582067

PGAM2
Phosphoglycerate mutase 2

2

13

High-throughput

0.783

High

582115

KATL1
Katanin p60 ATPase-containing subunit A-like 1

2

4

High-throughput

0.606

High

582128

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

2

0

High-throughput

0.580

High

582086

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.561

High

582096

CLVS2
Clavesin-2

2

1

High-throughput

0.553

High

194805

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

1

High-throughput

0.536

High

563126

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

582070

KLK2
Kallikrein-2

1

1

High-throughput

0.536

High

582072

DNJB2
DnaJ homolog subfamily B member 2

1

1

High-throughput

0.536

High

582075

SOX5
Transcription factor SOX-5

1

2

High-throughput

0.536

High

582085

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.536

High

582087

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

2

High-throughput

0.536

High

582109

BIRC7
Baculoviral IAP repeat-containing protein 7

1

1

High-throughput

0.536

High

582121

STK36
Serine/threonine-protein kinase 36

1

4

High-throughput

0.536

High

387093

TNNC2
Troponin C, skeletal muscle

1

1

High-throughput

0.515

High

452151

PDIA1
Protein disulfide-isomerase

1

6

High-throughput

0.515

High

582078

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.513

High

582080

ST1A1
Sulfotransferase 1A1

1

0

High-throughput

0.513

High

582081

VASP
Vasodilator-stimulated phosphoprotein

1

0

High-throughput

0.513

High

582082

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

High-throughput

0.513

High

582088

RIPP1
Protein ripply1

1

0

High-throughput

0.513

High

582089

ILK
Scaffold protein ILK

1

0

High-throughput

0.513

High

582090

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

0

High-throughput

0.513

High

582091

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.513

High

582103

ZN444
Zinc finger protein 444

1

0

High-throughput

0.513

High

582113

HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3

1

0

High-throughput

0.513

High

582126

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.513

High

582071

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.493

High

582129

PXMP4
Peroxisomal membrane protein 4

1

0

High-throughput

0.493

High

582074

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

2

High-throughput

0.489

High

582077

LPAR6
Lysophosphatidic acid receptor 6

1

1

High-throughput

0.489

High

582117

CNTP3
Contactin-associated protein-like 3

1

1

High-throughput

0.489

High

259379

BRD4
Bromodomain-containing protein 4

1

2

Small-scale

0.479

High

507492

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

Small-scale

0.479

High

582073

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.479

High

582083

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

582092

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

5

High-throughput

0.479

High

582094

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

582095

CCDC6
Coiled-coil domain-containing protein 6

1

1

High-throughput

0.479

High

582097

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

582100

THOC4
THO complex subunit 4

1

1

High-throughput

0.479

High

582101

ARHGP
Rho guanine nucleotide exchange factor 25

1

4

High-throughput

0.479

High

582119

DNJC4
DnaJ homolog subfamily C member 4

1

2

High-throughput

0.470

High

413124

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

582084

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.458

High

582120

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

582127

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

582118

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

High-throughput

0.445

High

582125

SHLB1
Endophilin-B1

1

2

High-throughput

0.445

High

582098

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

582105

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.437

High

582112

CASD1
N-acetylneuraminate

1

2

High-throughput

0.437

High

582068

EGLN
Endoglin

1

0

High-throughput

0.279

Low

582079

VEGFB
Vascular endothelial growth factor B

1

0

High-throughput

0.279

Low

582099

VASH1
Tubulinyl-Tyr carboxypeptidase 1

1

0

High-throughput

0.279

Low

582102

GNT2A
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase

1

0

High-throughput

0.279

Low

582106

DEN10
DENN domain-containing protein 10

1

0

High-throughput

0.279

Low

582108

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

582110

DCAF5
DDB1- and CUL4-associated factor 5

1

0

High-throughput

0.279

Low

582111

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

582114

CCM2
Cerebral cavernous malformations 2 protein

1

0

High-throughput

0.279

Low

582116

ORNT2
Mitochondrial ornithine transporter 2

1

0

High-throughput

0.279

Low

582122

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low

582123

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.279

Low

67196

LRIQ3
Leucine-rich repeat and IQ domain-containing protein 3

1

0

High-throughput

0.269

Low

154556

PLPP3
Phospholipid phosphatase 3

1

0

High-throughput

0.269

Low

582076

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.249

Low

582093

EPHA7
Ephrin type-A receptor 7

1

0

High-throughput

0.249

Low

582107

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.249

Low

582124

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025