Protein: SLPI
Antileukoproteinase (ALP) (BLPI) (HUSI-1) (Mucus proteinase inhibitor) (MPI) (Protease inhibitor WAP4) (Secretory leukocyte protease inhibitor) (Seminal proteinase inhibitor) (WAP four-disulfide core domain protein 4)

Gene: SLPI
Organism: Homo sapiens
Interactions: 30
UniProt ID: P03973

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003729 - mRNA binding
GO:0004866 - endopeptidase inhibitor activity
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226662

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

3

2

High-throughput

0.616

High

399398

ELNE
Neutrophil elastase

1

0

Small-scale

0.614

High

220336

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.580

High

399401

NBL1
Neuroblastoma suppressor of tumorigenicity 1

2

0

High-throughput

0.580

High

399406

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

0

High-throughput

0.580

High

399402

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.553

High

399414

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

2

High-throughput

0.553

High

399421

UBQL2
Ubiquilin-2

2

1

High-throughput

0.553

High

399422

UBQL1
Ubiquilin-1

2

1

High-throughput

0.553

High

180465

PLS1
Phospholipid scramblase 1

1

0

Small-scale

0.529

High

399400

GRN
Progranulin

1

2

Small-scale

0.515

High

399419

SRPK1
SRSF protein kinase 1

1

0

High-throughput

0.513

High

399415

TRI11
E3 ubiquitin-protein ligase TRIM11

1

0

High-throughput

0.493

High

399403

MMP14
Matrix metalloproteinase-14

1

0

Small-scale

0.480

High

217693

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

399399

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

399404

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

399405

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

Small-scale

0.458

High

399413

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

399411

FAM9B
Protein FAM9B

3

0

High-throughput

0.352

High

399407

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

399412

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

399416

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

399417

CIB3
Calcium and integrin-binding family member 3

2

0

High-throughput

0.316

High

399418

SIM14
Small integral membrane protein 14

2

0

High-throughput

0.316

High

399420

CABP8
Calcium-binding protein 8

2

0

High-throughput

0.316

High

399408

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

0

High-throughput

0.300

High

399409

IKBB
NF-kappa-B inhibitor beta

1

0

High-throughput

0.249

Low

399410

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

399423

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025