Protein: PIHD2
PIH1 domain-containing protein 2

Gene: PIHD2, PIH1D2
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q8WWB5

Gene Ontology (top 5):
GO:0000492 - box C/D snoRNP assembly
GO:0005737 - cytoplasm
GO:0006364 - rRNA processing
GO:0031267 - small GTPase binding
GO:0050821 - protein stabilization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1359117

PIHD2
PIH1 domain-containing protein 2

1

1

High-throughput

0.698

High

1103008

CENPR
Centromere protein R

4

0

High-throughput

0.668

High

1359119

DPH3
Diphthamide biosynthesis protein 3

3

0

High-throughput

0.646

High

1359125

MDFI
MyoD family inhibitor

3

0

High-throughput

0.646

High

570525

GFAP
Glial fibrillary acidic protein

2

4

High-throughput

0.628

High

1048938

REL
Proto-oncogene c-Rel

2

2

High-throughput

0.628

High

140382

SDCB1
Syntenin-1

2

1

High-throughput

0.606

High

180349

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

2

High-throughput

0.606

High

253519

ANM3
Protein arginine N-methyltransferase 3

2

3

High-throughput

0.606

High

1309339

CDKL3
Cyclin-dependent kinase-like 3

2

1

High-throughput

0.606

High

1330528

CBLL2
E3 ubiquitin-protein ligase CBLL2

2

2

High-throughput

0.606

High

1359132

EXOS5
Exosome complex component RRP46

2

1

High-throughput

0.606

High

1279666

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

3

1

High-throughput

0.603

High

183357

ZN185
Zinc finger protein 185

2

0

High-throughput

0.580

High

220283

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.580

High

347837

BAG3
BAG family molecular chaperone regulator 3

2

0

High-throughput

0.580

High

705832

AMPL
Cytosol aminopeptidase

2

0

High-throughput

0.580

High

1006276

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.580

High

1331994

BANP
Protein BANP

2

0

High-throughput

0.580

High

1356615

CT55
Cancer/testis antigen 55

2

0

High-throughput

0.580

High

1359118

GASP2
G-protein coupled receptor-associated sorting protein 2

2

0

High-throughput

0.580

High

1359136

NXF1
Nuclear RNA export factor 1

2

0

High-throughput

0.580

High

1359138

SRTD1
SERTA domain-containing protein 1

2

0

High-throughput

0.580

High

135287

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

2

6

High-throughput

0.576

High

1124278

IF4A2
Eukaryotic initiation factor 4A-II

2

5

High-throughput

0.573

High

249177

DSCAM
Cell adhesion molecule DSCAM

2

2

High-throughput

0.553

High

606145

DESM
Desmin

2

4

High-throughput

0.553

High

634552

LMNB1
Lamin-B1

2

5

High-throughput

0.553

High

948366

KR122
Keratin-associated protein 12-2

2

1

High-throughput

0.553

High

1150142

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.553

High

1160838

NFIL3
Nuclear factor interleukin-3-regulated protein

2

1

High-throughput

0.553

High

1218943

TASO2
Protein TASOR 2

2

1

High-throughput

0.553

High

1278720

ZN438
Zinc finger protein 438

2

2

High-throughput

0.553

High

1309134

MISP
Mitotic interactor and substrate of PLK1

2

1

High-throughput

0.553

High

1359131

CBX8
Chromobox protein homolog 8

2

1

High-throughput

0.553

High

1359139

CDC23
Cell division cycle protein 23 homolog

2

1

High-throughput

0.553

High

767281

MERL
Merlin

1

4

High-throughput

0.515

High

833325

PERI
Peripherin

1

4

High-throughput

0.515

High

843810

HD
Huntingtin

1

0

High-throughput

0.493

High

1131982

MVP
Major vault protein

1

1

High-throughput

0.481

High

1359142

X5D778
Ankyrin repeat domain 11 isoform A

1

3

High-throughput

0.470

High

593171

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

1359143

X5D7R7
Major vault protein

1

1

High-throughput

0.457

High

539832

RALA
Ras-related protein Ral-A

1

2

Small-scale

0.439

High

1247958

ANR11
Ankyrin repeat domain-containing protein 11

1

2

High-throughput

0.439

High

157666

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

1359121

MR1L1
MORF4 family-associated protein 1-like 1

4

0

High-throughput

0.365

High

949669

KR124
Keratin-associated protein 12-4

3

0

High-throughput

0.352

High

70979

NOTO
Homeobox protein notochord

2

0

High-throughput

0.316

High

399412

SLPI
Antileukoproteinase

2

0

High-throughput

0.316

High

505749

ZN688
Zinc finger protein 688

2

0

High-throughput

0.316

High

619256

TNNI1
Troponin I, slow skeletal muscle

2

0

High-throughput

0.316

High

892054

TAF6
Transcription initiation factor TFIID subunit 6

2

0

High-throughput

0.316

High

907170

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.316

High

948249

MCCD1
Mitochondrial coiled-coil domain protein 1

2

0

High-throughput

0.316

High

1177917

RSPO4
R-spondin-4

2

0

High-throughput

0.316

High

1200137

BOREA
Borealin

2

0

High-throughput

0.316

High

1220028

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

1315375

CF206
Cilia- and flagella-associated protein 206

2

0

High-throughput

0.316

High

1332358

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.316

High

1347689

ZN417
Zinc finger protein 417

2

0

High-throughput

0.316

High

1359120

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

1359122

GMCL1
Germ cell-less protein-like 1

2

0

High-throughput

0.316

High

1359123

TBATA
Protein TBATA

2

0

High-throughput

0.316

High

1359124

CCNL2
Cyclin-L2

2

0

High-throughput

0.316

High

1359126

SSX3
Protein SSX3

2

0

High-throughput

0.316

High

1359127

HES7
Transcription factor HES-7

2

0

High-throughput

0.316

High

1359128

PBX4
Pre-B-cell leukemia transcription factor 4

2

0

High-throughput

0.316

High

1359130

MED20
Mediator of RNA polymerase II transcription subunit 20

2

0

High-throughput

0.316

High

1359133

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

0

High-throughput

0.316

High

1359134

PKHJ1
Pleckstrin homology domain-containing family J member 1

2

0

High-throughput

0.316

High

1359135

COMD3
COMM domain-containing protein 3

2

0

High-throughput

0.316

High

1359137

ZMAT5
Zinc finger matrin-type protein 5

2

0

High-throughput

0.316

High

1359140

HSF4
Heat shock factor protein 4

2

0

High-throughput

0.316

High

1359141

ZBTB1
Zinc finger and BTB domain-containing protein 1

2

0

High-throughput

0.316

High

216763

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.268

Low

1205201

NHSL2
NHS-like protein 2

1

0

High-throughput

0.268

Low

1359129

ENKD1
Enkurin domain-containing protein 1

1

0

High-throughput

0.268

Low

558995

LYL1
Protein lyl-1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025