Protein: DCNL2
DCN1-like protein 2 (DCNL2) (DCUN1 domain-containing protein 2) (Defective in cullin neddylation protein 1-like protein 2)

Gene: DCNL2, DCUN1D2
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q6PH85

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0031624 - ubiquitin conjugating enzyme binding
GO:0032182 - ubiquitin-like protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1115254

CUL4B
Cullin-4B

4

20

Small-scale

0.903

High

1114898

CUL4A
Cullin-4A

4

20

Small-scale

0.896

High

1113434

CUL3
Cullin-3

3

20

Small-scale

0.883

High

1112556

CUL1
Cullin-1

3

20

Small-scale

0.861

High

1244459

CUL5
Cullin-5

3

20

Small-scale

0.861

High

1112882

CUL2
Cullin-2

4

20

Small-scale

0.804

High

957419

UBC12
NEDD8-conjugating enzyme Ubc12

4

10

Small-scale

0.698

High

1244461

DCNL1
DCN1-like protein 1

1

2

High-throughput

0.691

High

983845

RBX1
E3 ubiquitin-protein ligase RBX1

1

9

Small-scale

0.618

High

1244464

RBX2
RING-box protein 2

1

9

Small-scale

0.618

High

1244454

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

Small-scale

0.561

High

1147181

ELOB
Elongin-B

1

2

Small-scale

0.553

High

320826

KLH18
Kelch-like protein 18

1

9

High-throughput

0.536

High

1122261

SCRIB
Protein scribble homolog

1

2

High-throughput

0.536

High

1244453

KLH24
Kelch-like protein 24

1

10

High-throughput

0.536

High

1244458

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

12

High-throughput

0.536

High

1244466

FEM1B
Protein fem-1 homolog B

1

1

High-throughput

0.536

High

187364

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.513

High

607305

NEUM
Neuromodulin

1

0

High-throughput

0.513

High

1244455

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.513

High

1244456

CARM1
Histone-arginine methyltransferase CARM1

1

0

High-throughput

0.513

High

1244457

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.513

High

1244465

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

0

High-throughput

0.513

High

1098799

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

1

Small-scale

0.501

High

1244460

UBE2F
NEDD8-conjugating enzyme UBE2F

1

10

Small-scale

0.501

High

1244463

KLH42
Kelch-like protein 42

1

12

High-throughput

0.489

High

1244467

KCTD3
BTB/POZ domain-containing protein KCTD3

1

4

High-throughput

0.489

High

422363

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1202195

DCAF6
DDB1- and CUL4-associated factor 6

1

1

High-throughput

0.479

High

1244462

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High


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Last updated: 11Aug2025