Protein: LTOR5
Ragulator complex protein LAMTOR5 (Hepatitis B virus X-interacting protein) (HBV X-interacting protein) (HBX-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5)

Gene: LTOR5, LAMTOR5
Organism: Homo sapiens
Interactions: 159
UniProt ID: O43504

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0008361 - regulation of cell size
GO:0009615 - response to virus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

219250

LTOR2
Ragulator complex protein LAMTOR2

6

0

Small-scale

0.902

High

219243

LTOR3
Ragulator complex protein LAMTOR3

4

0

Small-scale

0.841

High

219161

LTOR4
Ragulator complex protein LAMTOR4

10

0

Small-scale

0.726

High

219158

ZBT16
Zinc finger and BTB domain-containing protein 16

5

0

High-throughput

0.695

High

219233

RRAGC
Ras-related GTP-binding protein C

4

3

Small-scale

0.687

High

219201

S38A9
Neutral amino acid transporter 9

5

0

Small-scale

0.682

High

219185

LTOR1
Ragulator complex protein LAMTOR1

4

0

Small-scale

0.670

High

219184

RRAGB
Ras-related GTP-binding protein B

3

3

Small-scale

0.662

High

219191

RRAGA
Ras-related GTP-binding protein A

3

3

Small-scale

0.662

High

219235

RRAGD
Ras-related GTP-binding protein D

3

3

High-throughput

0.662

High

219203

CEP70
Centrosomal protein of 70 kDa

3

0

High-throughput

0.646

High

185054

TELT
Telethonin

3

0

High-throughput

0.639

High

219199

RPTOR
Regulatory-associated protein of mTOR

3

0

Small-scale

0.634

High

219251

GIT1
ARF GTPase-activating protein GIT1

2

1

High-throughput

0.632

High

188622

BIRC5
Baculoviral IAP repeat-containing protein 5

3

0

Small-scale

0.625

High

219153

EF1A1
Elongation factor 1-alpha 1

2

0

High-throughput

0.605

High

219228

ITPA
Inosine triphosphate pyrophosphatase

2

0

High-throughput

0.576

High

219172

NCOA6
Nuclear receptor coactivator 6

1

0

Small-scale

0.549

High

219133

MYF6
Myogenic factor 6

1

1

High-throughput

0.541

High

219135

HSPA9
Stress-70 protein, mitochondrial

1

1

High-throughput

0.541

High

219169

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

High-throughput

0.541

High

219245

MKLN1
Muskelin

1

1

High-throughput

0.541

High

219117

P53
Cellular tumor antigen p53

1

0

Small-scale

0.537

High

219168

KEAP1
Kelch-like ECH-associated protein 1

1

0

Small-scale

0.537

High

219140

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.536

High

219162

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.536

High

219177

STK38
Serine/threonine-protein kinase 38

1

1

High-throughput

0.536

High

219207

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.536

High

219239

UBIP1
Upstream-binding protein 1

1

1

High-throughput

0.536

High

219248

ST38L
Serine/threonine-protein kinase 38-like

1

1

High-throughput

0.536

High

219253

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.536

High

219102

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.518

High

219116

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.518

High

219123

MYH3
Myosin-3

1

0

High-throughput

0.518

High

219132

SFPQ
Splicing factor, proline- and glutamine-rich

1

0

High-throughput

0.518

High

219134

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.518

High

219141

MSS4
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.518

High

219145

AK1C2
Aldo-keto reductase family 1 member C2

1

0

High-throughput

0.518

High

219152

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.518

High

219167

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.518

High

219178

SHB
SH2 domain-containing adapter protein B

1

0

High-throughput

0.518

High

219194

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.518

High

219198

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

0

High-throughput

0.518

High

219215

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.518

High

219222

HTF4
Transcription factor 12

1

0

High-throughput

0.518

High

219226

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.518

High

219230

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

1

0

High-throughput

0.518

High

219231

ECT2
Protein ECT2

1

0

High-throughput

0.518

High

219254

SNX5
Sorting nexin-5

1

0

High-throughput

0.518

High

219246

UBQL1
Ubiquilin-1

1

1

High-throughput

0.515

High

190284

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

219103

RENR
Renin receptor

1

0

High-throughput

0.513

High

219104

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.513

High

219125

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.513

High

219139

HD
Huntingtin

1

0

High-throughput

0.513

High

219148

ALR
FAD-linked sulfhydryl oxidase ALR

1

0

High-throughput

0.513

High

219150

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

219154

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

0

High-throughput

0.513

High

219164

CDC16
Cell division cycle protein 16 homolog

1

0

High-throughput

0.513

High

219171

FHL2
Four and a half LIM domains protein 2

1

0

High-throughput

0.513

High

219176

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

219181

DNLZ
DNL-type zinc finger protein

1

0

High-throughput

0.513

High

219188

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

0

High-throughput

0.513

High

219190

MOB2
MOB kinase activator 2

1

0

High-throughput

0.513

High

219193

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.513

High

219219

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

0

High-throughput

0.513

High

219223

SORT
Sortilin

1

0

High-throughput

0.513

High

219224

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.513

High

219234

GBA2
Non-lysosomal glucosylceramidase

1

0

High-throughput

0.513

High

219240

FNIP2
Folliculin-interacting protein 2

1

0

High-throughput

0.513

High

219247

TTF2
Transcription termination factor 2

1

0

High-throughput

0.513

High

219128

MYOG
Myogenin

1

1

High-throughput

0.494

High

219159

PPARA
Peroxisome proliferator-activated receptor alpha

1

2

High-throughput

0.494

High

219170

GIT2
ARF GTPase-activating protein GIT2

1

1

High-throughput

0.494

High

219197

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

1

2

High-throughput

0.494

High

219119

GELS
Gelsolin

1

0

High-throughput

0.493

High

219142

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

219146

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

219186

S18B1
MFS-type transporter SLC18B1

1

1

High-throughput

0.489

High

219237

KBRS2
NF-kappa-B inhibitor-interacting Ras-like protein 2

1

1

High-throughput

0.489

High

219107

RASN
GTPase NRas

1

2

High-throughput

0.479

High

219108

RASH
GTPase HRas

1

2

High-throughput

0.479

High

219109

RASK
GTPase KRas

1

2

High-throughput

0.479

High

219126

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

219127

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

219147

NR1H2
Oxysterols receptor LXR-beta

1

2

Small-scale

0.479

High

219149

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

219151

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.479

High

219156

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

219166

NR1H3
Oxysterols receptor LXR-alpha

1

2

Small-scale

0.479

High

219110

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

Small-scale

0.460

High

219112

RET4
Retinol-binding protein 4

1

0

Small-scale

0.460

High

219113

ALBU
Albumin

1

0

Small-scale

0.460

High

219114

MT2
Metallothionein-2

1

0

Small-scale

0.460

High

219115

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

Small-scale

0.460

High

219157

TOP2B
DNA topoisomerase 2-beta

1

0

Small-scale

0.460

High

219179

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.460

High

219180

GASP1
G-protein coupled receptor-associated sorting protein 1

1

0

High-throughput

0.460

High

219208

BHMT1
Betaine--homocysteine S-methyltransferase 1

1

0

Small-scale

0.460

High

219144

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.458

High

219155

E2F1
Transcription factor E2F1

1

0

Small-scale

0.458

High

219163

TP4A2
Protein tyrosine phosphatase type IVA 2

1

0

Small-scale

0.458

High

219165

STK4
Serine/threonine-protein kinase 4

1

0

Small-scale

0.458

High

219173

STAT4
Signal transducer and activator of transcription 4

1

0

Small-scale

0.458

High

219192

NUFP2
FMR1-interacting protein NUFIP2

1

0

Small-scale

0.458

High

219221

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.458

High

219242

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

219210

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.439

High

219229

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.439

High

219212

VOPP1
WW domain binding protein VOPP1

1

0

High-throughput

0.438

High

219129

RHOQ
Rho-related GTP-binding protein RhoQ

1

3

High-throughput

0.437

High

219122

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

219124

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.426

High

219137

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.426

High

219187

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.426

High

219200

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.426

High

219206

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.426

High

219236

S17A5
Sialin

1

0

High-throughput

0.426

High

219227

S46A2
Solute carrier family 46 member 2

1

1

High-throughput

0.407

High

219218

BORC6
BLOC-1-related complex subunit 6

2

0

High-throughput

0.318

High

219143

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

219101

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.282

High

219118

ITB1
Integrin beta-1

1

0

High-throughput

0.282

High

219138

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.282

High

219195

ANR46
Ankyrin repeat domain-containing protein 46

1

0

High-throughput

0.282

High

219205

ZN592
Zinc finger protein 592

1

0

High-throughput

0.282

High

219238

CLIC5
Chloride intracellular channel protein 5

1

0

High-throughput

0.282

High

219241

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

219255

HEBP2
Heme-binding protein 2

1

0

High-throughput

0.282

High

215738

ERI3
ERI1 exoribonuclease 3

1

0

High-throughput

0.279

Low

219189

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.279

Low

219196

STX12
Syntaxin-12

1

0

High-throughput

0.279

Low

219204

SEN15
tRNA-splicing endonuclease subunit Sen15

1

0

High-throughput

0.279

Low

219209

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.279

Low

219211

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

0

High-throughput

0.279

Low

219213

BORC7
BLOC-1-related complex subunit 7

1

0

High-throughput

0.279

Low

219214

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

0

High-throughput

0.279

Low

219216

BORC8
BLOC-1-related complex subunit 8

1

0

High-throughput

0.279

Low

219217

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.279

Low

219225

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

219232

MTD2L
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial

1

0

High-throughput

0.279

Low

219244

TRM6
tRNA

1

0

High-throughput

0.279

Low

219249

SAC2
Phosphatidylinositide phosphatase SAC2

1

0

High-throughput

0.279

Low

219130

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

219160

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

219174

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

219252

KAD6
Adenylate kinase isoenzyme 6

1

0

High-throughput

0.268

Low

219105

CFAB
Complement factor B

1

0

Small-scale

0.251

Low

219106

A1AT
Alpha-1-antitrypsin

1

0

Small-scale

0.251

Low

219111

CO9
Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b]

1

0

Small-scale

0.251

Low

219120

ACBP
Acyl-CoA-binding protein

1

0

Small-scale

0.251

Low

219121

ASGR1
Asialoglycoprotein receptor 1

1

0

Small-scale

0.251

Low

219175

PDK1
[Pyruvate dehydrogenase

1

0

Small-scale

0.251

Low

219182

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

219202

MCPH1
Microcephalin

1

0

Small-scale

0.251

Low

219220

YTDC1
YTH domain-containing protein 1

1

0

High-throughput

0.251

Low

219183

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.238

Low

219131

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

219136

S19A1
Reduced folate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025