Protein: STYK1
Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)

Gene: STYK1
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q6J9G0

Gene Ontology (top 5):
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

461592

HS90A
Heat shock protein HSP 90-alpha

3

20

High-throughput

0.852

High

468494

HS90B
Heat shock protein HSP 90-beta

3

20

High-throughput

0.847

High

1235288

STYK1
Tyrosine-protein kinase STYK1

1

17

Small-scale

0.724

High

1158376

CDC37
Hsp90 co-chaperone Cdc37

2

20

High-throughput

0.714

High

123917

MYO1F
Unconventional myosin-If

1

16

High-throughput

0.691

High

911982

DGKE
Diacylglycerol kinase epsilon

1

4

High-throughput

0.691

High

891623

GSK3B
Glycogen synthase kinase-3 beta

1

11

Small-scale

0.646

High

1235310

ASTRA
Protein Aster-A

2

3

High-throughput

0.628

High

410902

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

1160659

DREB
Drebrin

1

9

High-throughput

0.618

High

348145

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

20

High-throughput

0.618

High

692082

MARK3
MAP/microtubule affinity-regulating kinase 3

1

8

High-throughput

0.618

High

699779

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

710306

EPHA2
Ephrin type-A receptor 2

1

19

High-throughput

0.618

High

987708

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

1090146

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

20

High-throughput

0.618

High

1122259

SCRIB
Protein scribble homolog

1

20

High-throughput

0.618

High

1235292

MARK2
Serine/threonine-protein kinase MARK2

1

9

High-throughput

0.618

High

1235295

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

13

High-throughput

0.618

High

1235299

EHBP1
EH domain-binding protein 1

1

19

High-throughput

0.618

High

1235316

ERBIN
Erbin

1

20

High-throughput

0.618

High

1235318

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

6

Small-scale

0.618

High

1235334

PKHA1
Pleckstrin homology domain-containing family A member 1

1

20

High-throughput

0.618

High

1235348

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.618

High

1120744

DSG2
Desmoglein-2

2

20

High-throughput

0.611

High

1201980

H90B4
Putative heat shock protein HSP 90-beta 4

1

20

High-throughput

0.575

High

1202051

HS905
Putative heat shock protein HSP 90-alpha A5

1

20

High-throughput

0.575

High

1235300

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

11

Small-scale

0.561

High

906076

AL3A2
Aldehyde dehydrogenase family 3 member A2

2

5

High-throughput

0.558

High

136400

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.553

High

611173

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

High-throughput

0.553

High

1040316

DYST
Dystonin

1

15

High-throughput

0.553

High

1053682

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.553

High

1106484

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.553

High

1235333

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.553

High

420573

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.536

High

675058

TNR6
Tumor necrosis factor receptor superfamily member 6

1

12

High-throughput

0.536

High

774419

BASI
Basigin

1

20

High-throughput

0.536

High

1008195

PRKDC
DNA-dependent protein kinase catalytic subunit

1

9

High-throughput

0.536

High

1235301

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

3

High-throughput

0.536

High

1235345

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

6

High-throughput

0.536

High

1214869

WLS
Protein wntless homolog

1

0

High-throughput

0.513

High

1126705

BECN1
Beclin-1

1

4

Small-scale

0.512

High

123735

MYO1C
Unconventional myosin-Ic

1

16

High-throughput

0.500

High

227905

MYO1B
Unconventional myosin-Ib

1

15

High-throughput

0.500

High

318341

MYO1D
Unconventional myosin-Id

1

16

High-throughput

0.500

High

321268

ERLN2
Erlin-2

1

5

High-throughput

0.500

High

1032487

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

5

High-throughput

0.500

High

1235340

T106B
Transmembrane protein 106B

1

1

High-throughput

0.500

High

172946

XPO1
Exportin-1

1

6

High-throughput

0.489

High

243957

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

12

High-throughput

0.489

High

698765

CALX
Calnexin

1

7

High-throughput

0.489

High

894819

EMD
Emerin

1

7

High-throughput

0.489

High

963084

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.489

High

1209954

TM201
Transmembrane protein 201

1

1

High-throughput

0.489

High

1235308

NU205
Nuclear pore complex protein Nup205

1

3

High-throughput

0.489

High

1235312

RN185
E3 ubiquitin-protein ligase RNF185

1

7

High-throughput

0.489

High

1235322

T106C
Transmembrane protein 106C

1

1

High-throughput

0.489

High

1235324

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.489

High

1235341

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

2

High-throughput

0.489

High

1235342

NSMA3
Sphingomyelin phosphodiesterase 4

1

1

High-throughput

0.489

High

1235353

SGT1
Protein SGT1 homolog

1

6

High-throughput

0.489

High

178795

SCAM1
Secretory carrier-associated membrane protein 1

1

3

High-throughput

0.479

High

271263

CPNE3
Copine-3

1

6

High-throughput

0.479

High

299998

CBPD
Carboxypeptidase D

1

8

High-throughput

0.479

High

333050

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

11

High-throughput

0.479

High

338630

AGRL2
Adhesion G protein-coupled receptor L2

1

13

High-throughput

0.479

High

467521

4F2
Amino acid transporter heavy chain SLC3A2

1

3

High-throughput

0.479

High

577798

PLAK
Junction plakoglobin

1

20

High-throughput

0.479

High

612249

ARF4
ADP-ribosylation factor 4

1

12

High-throughput

0.479

High

661285

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

9

High-throughput

0.479

High

898092

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

16

High-throughput

0.479

High

921693

COPB
Coatomer subunit beta

1

6

High-throughput

0.479

High

1036995

DSC2
Desmocollin-2

1

20

High-throughput

0.479

High

1047583

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.479

High

1058466

CKAP4
Cytoskeleton-associated protein 4

1

11

High-throughput

0.479

High

1107556

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

4

High-throughput

0.479

High

1111568

STIM1
Stromal interaction molecule 1

1

9

High-throughput

0.479

High

1139453

S39AE
Metal cation symporter ZIP14

1

9

High-throughput

0.479

High

1153256

AAAT
Neutral amino acid transporter B(0)

1

11

High-throughput

0.479

High

1154647

VAMP3
Vesicle-associated membrane protein 3

1

4

High-throughput

0.479

High

1159695

OCLN
Occludin

1

7

High-throughput

0.479

High

1164244

VATF
V-type proton ATPase subunit F

1

2

High-throughput

0.479

High

1186400

ASTRB
Protein Aster-B

1

3

High-throughput

0.479

High

1218241

F1711
Protein FAM171A1

1

17

High-throughput

0.479

High

1235290

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

1235296

UNC5B
Netrin receptor UNC5B

1

17

High-throughput

0.479

High

1235297

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

1

1

High-throughput

0.479

High

1235302

NBEA
Neurobeachin

1

15

High-throughput

0.479

High

1235303

VANG1
Vang-like protein 1

1

10

High-throughput

0.479

High

1235304

DLG5
Disks large homolog 5

1

20

High-throughput

0.479

High

1235309

US6NL
USP6 N-terminal-like protein

1

13

High-throughput

0.479

High

1235321

ESYT1
Extended synaptotagmin-1

1

9

High-throughput

0.479

High

1235323

RFIP5
Rab11 family-interacting protein 5

1

10

High-throughput

0.479

High

1235326

ZDHC5
Palmitoyltransferase ZDHHC5

1

7

High-throughput

0.479

High

1235328

S38A1
Sodium-coupled neutral amino acid symporter 1

1

3

High-throughput

0.479

High

1235329

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

10

High-throughput

0.479

High

1235336

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.479

High

1235337

JPH1
Junctophilin-1

1

8

High-throughput

0.479

High

1235338

WDR6
tRNA

1

13

High-throughput

0.479

High

1235346

DNJB4
DnaJ homolog subfamily B member 4

1

9

High-throughput

0.479

High

1235351

NISCH
Nischarin

1

20

High-throughput

0.479

High

1235355

S4A7
Sodium bicarbonate cotransporter 3

1

8

High-throughput

0.479

High

137742

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

3

High-throughput

0.457

High

389744

FETUA
Alpha-2-HS-glycoprotein

1

5

High-throughput

0.457

High

1205341

MDH1B
Putative malate dehydrogenase 1B

1

2

High-throughput

0.457

High

1235298

ZN561
Zinc finger protein 561

1

3

High-throughput

0.457

High

1235306

S39A7
Zinc transporter SLC39A7

1

9

High-throughput

0.457

High

71338

F1712
Protein FAM171A2

1

17

High-throughput

0.437

High

126125

AP3B1
AP-3 complex subunit beta-1

1

9

High-throughput

0.437

High

158234

COPE
Coatomer subunit epsilon

1

4

High-throughput

0.437

High

169600

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.437

High

174253

ARHGA
Rho guanine nucleotide exchange factor 10

1

20

High-throughput

0.437

High

181336

PGRC2
Membrane-associated progesterone receptor component 2

1

5

High-throughput

0.437

High

230039

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

8

High-throughput

0.437

High

291384

NU155
Nuclear pore complex protein Nup155

1

6

High-throughput

0.437

High

336116

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

20

High-throughput

0.437

High

338340

SC24A
Protein transport protein Sec24A

1

20

High-throughput

0.437

High

338494

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.437

High

469103

SRPRA
Signal recognition particle receptor subunit alpha

1

4

High-throughput

0.437

High

773539

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.437

High

873247

COPD
Coatomer subunit delta

1

5

High-throughput

0.437

High

921923

COPA
Coatomer subunit alpha

1

7

High-throughput

0.437

High

992800

RACK1
Small ribosomal subunit protein RACK1

1

5

Small-scale

0.437

High

1148898

SC23A
Protein transport protein Sec23A

1

20

High-throughput

0.437

High

1148986

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.437

High

1233125

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

5

High-throughput

0.437

High

1235289

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

10

High-throughput

0.437

High

1235293

VP13B
Intermembrane lipid transfer protein VPS13B

1

3

High-throughput

0.437

High

1235294

LRC49
Leucine-rich repeat-containing protein 49

1

20

High-throughput

0.437

High

1235305

DEP1B
DEP domain-containing protein 1B

1

17

High-throughput

0.437

High

1235307

TBCD5
TBC1 domain family member 5

1

16

High-throughput

0.437

High

1235313

GRM2B
GRAM domain-containing protein 2B

1

3

High-throughput

0.437

High

1235314

SAHH3
Adenosylhomocysteinase 3

1

8

High-throughput

0.437

High

1235315

CK5P3
CDK5 regulatory subunit-associated protein 3

1

3

High-throughput

0.437

High

1235317

CLCC1
Chloride channel CLIC-like protein 1

1

4

High-throughput

0.437

High

1235319

CDCA3
Cell division cycle-associated protein 3

1

8

High-throughput

0.437

High

1235325

SPY4
Protein sprouty homolog 4

1

6

High-throughput

0.437

High

1235327

TANC1
Protein TANC1

1

17

High-throughput

0.437

High

1235330

GCP60
Golgi resident protein GCP60

1

12

High-throughput

0.437

High

1235332

GORS2
Golgi reassembly-stacking protein 2

1

12

High-throughput

0.437

High

1235339

VPS45
Vacuolar protein sorting-associated protein 45

1

12

High-throughput

0.437

High

1235343

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.437

High

1235347

TRM7
tRNA

1

6

High-throughput

0.437

High

1235349

KDIS
Kinase D-interacting substrate of 220 kDa

1

14

High-throughput

0.437

High

1235350

SAC2
Phosphatidylinositide phosphatase SAC2

1

3

High-throughput

0.437

High

1235352

MAN1
Inner nuclear membrane protein Man1

1

7

High-throughput

0.437

High

1197237

MBRL
Membralin

3

0

High-throughput

0.349

High

1235291

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.292

High

1203059

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.279

Low

1235320

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.279

Low

1235331

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

1235335

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.279

Low

1235344

SENP1
Sentrin-specific protease 1

1

0

High-throughput

0.279

Low

1235311

NRBF2
Nuclear receptor-binding factor 2

1

0

Small-scale

0.249

Low

1235354

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025