Protein: I22R2
Interleukin-22 receptor subunit alpha-2 (IL-22 receptor subunit alpha-2) (IL-22R-alpha-2) (IL-22RA2) (Cytokine receptor class-II member 10) (Cytokine receptor family 2 member 10) (CRF2-10) (Cytokine receptor family type 2, soluble 1) (CRF2-S1) (Interleukin-22-binding protein) (IL-22BP) (IL22BP) (ZcytoR16)

Gene: I22R2, IL22RA2
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q969J5

Gene Ontology (top 5):
GO:0004896 - cytokine receptor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1380393

IL22
Interleukin-22

5

3

Small-scale

0.919

High

1329600

I22R1
Interleukin-22 receptor subunit alpha-1

1

10

Small-scale

0.618

High

522716

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

4

High-throughput

0.536

High

1126039

GAS6
Growth arrest-specific protein 6

1

1

High-throughput

0.536

High

1380390

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

1380391

NAR5
Ecto-ADP-ribosyltransferase 5

1

0

High-throughput

0.513

High

1380394

PYRG2
CTP synthase 2

1

0

High-throughput

0.513

High

1287398

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.489

High

1380389

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.445

High

249998

OGA
Protein O-GlcNAcase

1

0

High-throughput

0.426

High

1163933

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.426

High

1380392

THUM3
tRNA

1

0

High-throughput

0.426

High

636027

PRPS3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.279

Low

1105532

OS9
Protein OS-9

1

0

High-throughput

0.279

Low

1380396

FA8A1
Protein FAM8A1

1

0

High-throughput

0.279

Low

1380397

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.279

Low

1380398

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

0

High-throughput

0.279

Low

1380388

TBC31
TBC1 domain family member 31

1

0

High-throughput

0.269

Low

212985

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.232

Low

1380395

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025