Protein: UPP1
Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3)

Gene: UPP1
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q16831

Gene Ontology (top 5):
GO:0004850 - uridine phosphorylase activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006139 - nucleobase-containing compound metabolic process
GO:0006218 - uridine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

474707

VIME
Vimentin

1

1

Small-scale

0.536

High

1163922

WDR59
GATOR2 complex protein WDR59

1

1

High-throughput

0.536

High

315644

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.513

High

904296

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.513

High

905583

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

1023788

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

1093359

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.513

High

1116418

FHL1
Four and a half LIM domains protein 1

1

0

High-throughput

0.513

High

1134927

CUL7
Cullin-7

1

0

High-throughput

0.513

High

1153159

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

0

High-throughput

0.513

High

1163916

UBR4
E3 ubiquitin-protein ligase UBR4

1

0

High-throughput

0.513

High

1163921

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

0

High-throughput

0.513

High

1163923

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.513

High

1163925

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

0

High-throughput

0.513

High

1163926

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

1163927

SETX
Probable helicase senataxin

1

0

High-throughput

0.513

High

1163928

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.513

High

1163929

FCSK
L-fucose kinase

1

0

High-throughput

0.513

High

1163932

ALMS1
Centrosome-associated protein ALMS1

1

0

High-throughput

0.513

High

1163936

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.513

High

1163939

BBS2
BBSome complex member BBS2

1

0

High-throughput

0.513

High

1163941

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

0

High-throughput

0.513

High

1163944

PYRG2
CTP synthase 2

1

0

High-throughput

0.513

High

1163945

RIC8B
Chaperone Ric-8B

1

0

High-throughput

0.513

High

1163947

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.513

High

1163954

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.513

High

247120

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.493

High

1163934

LRC45
Leucine-rich repeat-containing protein 45

1

0

High-throughput

0.493

High

1163949

ZNFX1
NFX1-type zinc finger-containing protein 1

1

1

High-throughput

0.489

High

384424

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

1163953

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

Small-scale

0.480

High

1163913

SMU1
WD40 repeat-containing protein SMU1

1

1

High-throughput

0.479

High

1163950

APC7
Anaphase-promoting complex subunit 7

1

1

High-throughput

0.479

High

260027

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

888103

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

363350

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.458

High

400906

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

508054

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

537243

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

695590

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

984136

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

1088862

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1138263

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1163946

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.458

High

330168

VENTX
Homeobox protein VENTX

1

2

High-throughput

0.445

High

75674

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

258904

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.426

High

374631

RASH
GTPase HRas

1

0

High-throughput

0.426

High

733845

CDD
Cytidine deaminase

1

0

High-throughput

0.426

High

1029101

E2F1
Transcription factor E2F1

1

0

High-throughput

0.426

High

1163933

I22R2
Interleukin-22 receptor subunit alpha-2

1

0

High-throughput

0.426

High

1163937

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1163943

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.426

High

69497

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

379097

IGKC
Immunoglobulin kappa constant

1

3

High-throughput

0.407

High

379251

IGHG1
Immunoglobulin heavy constant gamma 1

1

3

High-throughput

0.407

High

379356

IGHG2
Immunoglobulin heavy constant gamma 2

1

3

High-throughput

0.407

High

379459

IGHG4
Immunoglobulin heavy constant gamma 4

1

3

High-throughput

0.407

High

1163915

Q4KMX6
Anaphase-promoting complex subunit 7

1

1

High-throughput

0.407

High

260690

CUTA
Protein CutA

3

0

High-throughput

0.345

High

158993

ZN195
Zinc finger protein 195

1

0

High-throughput

0.279

Low

325322

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

733362

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

789902

FDFT
Squalene synthase

1

0

High-throughput

0.279

Low

894470

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.279

Low

1129290

BLTP2
Bridge-like lipid transfer protein family member 2

1

0

High-throughput

0.279

Low

1163914

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1163917

PR14L
Protein PRR14L

1

0

High-throughput

0.279

Low

1163918

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.279

Low

1163919

GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1163920

ARMX5
Armadillo repeat-containing X-linked protein 5

1

0

High-throughput

0.279

Low

1163931

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.279

Low

1163938

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.279

Low

1163940

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

1163948

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.279

Low

1163951

MTUS1
Microtubule-associated tumor suppressor 1

1

0

High-throughput

0.279

Low

1163952

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

1163924

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

190368

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.232

Low

261181

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

1163930

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low

1163935

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.232

Low

1163942

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025