Protein: PRPS3
Ribose-phosphate pyrophosphokinase 3 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 1-like 1) (PRPS1-like 1) (Phosphoribosyl pyrophosphate synthase III) (PRS-III)

Gene: PRPS3, PRPS1L1
Organism: Homo sapiens
Interactions: 34
UniProt ID: P21108

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002189 - ribose phosphate diphosphokinase complex
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636017

PRPS1
Ribose-phosphate pyrophosphokinase 1

5

18

High-throughput

0.919

High

240056

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

3

16

High-throughput

0.855

High

549534

PRPS2
Ribose-phosphate pyrophosphokinase 2

2

18

High-throughput

0.789

High

141905

PODXL
Podocalyxin

1

1

High-throughput

0.536

High

636026

CSN5
COP9 signalosome complex subunit 5

1

7

High-throughput

0.536

High

391565

FRIH
Ferritin heavy chain

1

0

High-throughput

0.513

High

636023

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

636016

NXPH1
Neurexophilin-1

1

1

High-throughput

0.489

High

636018

FOXF2
Forkhead box protein F2

1

1

High-throughput

0.489

High

636031

GHITM
Growth hormone-inducible transmembrane protein

1

1

High-throughput

0.489

High

58696

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

2

High-throughput

0.479

High

271415

ATG13
Autophagy-related protein 13

1

1

High-throughput

0.479

High

626063

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

6

High-throughput

0.479

High

636013

BRD2
Bromodomain-containing protein 2

1

3

High-throughput

0.479

High

636014

CDK7
Cyclin-dependent kinase 7

1

5

High-throughput

0.479

High

636015

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.479

High

636020

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

636022

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

636028

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

636032

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

636037

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.479

High

636019

CND2
Condensin complex subunit 2

1

1

High-throughput

0.437

High

636025

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.437

High

636030

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.437

High

636033

ENY2
Transcription and mRNA export factor ENY2

1

1

High-throughput

0.437

High

636034

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.437

High

516226

PAL4G
Peptidyl-prolyl cis-trans isomerase A-like 4G

1

0

High-throughput

0.426

High

636021

RSLBA
Ras-like protein family member 11A

1

0

High-throughput

0.279

Low

636024

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.279

Low

636027

I22R2
Interleukin-22 receptor subunit alpha-2

1

0

High-throughput

0.279

Low

636029

NPS3B
Protein NipSnap homolog 3B

1

0

High-throughput

0.279

Low

636035

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.279

Low

636036

KLK5
Kallikrein-5

1

0

High-throughput

0.279

Low

192445

INSI1
Insulin-induced gene 1 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025