Protein: RN135
E3 ubiquitin-protein ligase RNF135 (EC 2.3.2.27) (RIG-I E3 ubiquitin ligase) (REUL) (RING finger protein 135) (RING finger protein leading to RIG-I activation) (Riplet) (RING-type E3 ubiquitin transferase RNF135)

Gene: RN135, RNF135
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q8IUD6

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010494 - cytoplasmic stress granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

321915

RIGI
Antiviral innate immune response receptor RIG-I

7

17

Small-scale

0.973

High

1216176

RN135
E3 ubiquitin-protein ligase RNF135

5

18

Small-scale

0.924

High

1139907

BSPRY
B box and SPRY domain-containing protein

2

16

High-throughput

0.811

High

1216183

CTNL1
Alpha-catulin

5

2

High-throughput

0.725

High

896487

UBE2N
Ubiquitin-conjugating enzyme E2 N

3

20

Small-scale

0.655

High

1216180

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

16

Small-scale

0.647

High

253081

HSF2B
Heat shock factor 2-binding protein

3

0

High-throughput

0.636

High

770628

TXLNA
Alpha-taxilin

2

16

High-throughput

0.628

High

1065957

IQCB1
IQ calmodulin-binding motif-containing protein 1

2

1

High-throughput

0.628

High

1216181

E41L5
Band 4.1-like protein 5

2

7

High-throughput

0.628

High

1216184

TES
Testin

2

4

High-throughput

0.628

High

1052702

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

19

Small-scale

0.618

High

995012

GOGA2
Golgin subfamily A member 2

3

7

High-throughput

0.616

High

1216179

AP4AT
AP-4 complex accessory subunit Tepsin

2

3

High-throughput

0.606

High

1033958

XRCC4
DNA repair protein XRCC4

2

0

High-throughput

0.602

High

1216178

DHX58
ATP-dependent RNA helicase DHX58

1

20

Small-scale

0.575

High

881220

CTBP2
C-terminal-binding protein 2

2

1

High-throughput

0.553

High

444547

K2C7
Keratin, type II cytoskeletal 7

1

5

High-throughput

0.536

High

1216182

KLH42
Kelch-like protein 42

1

4

High-throughput

0.536

High

1216186

TACC3
Transforming acidic coiled-coil-containing protein 3

1

4

High-throughput

0.536

High

919777

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

Small-scale

0.501

High

1081192

ENOX2
Ecto-NOX disulfide-thiol exchanger 2

1

1

High-throughput

0.481

High

1187654

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

3

Small-scale

0.479

High

1216185

PLAT4
Phospholipase A and acyltransferase 4

1

1

Small-scale

0.479

High

232297

KDM1A
Lysine-specific histone demethylase 1A

1

5

Small-scale

0.437

High

1216177

NIN
Ninein

1

7

High-throughput

0.437

High

1046793

TF2H2
General transcription factor IIH subunit 2

2

0

High-throughput

0.328

High


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Last updated: 15 Jul 2024