Protein: CYPH
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (CPH) (Cyclosporin A-binding protein) (PPI-II) (Rotamase)

Gene: CYPH, CPR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 189
UniProt ID: P14832

Gene Ontology (top 5):
GO:0003729 - mRNA binding
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

540516

CYPH
Peptidyl-prolyl cis-trans isomerase

3

7

High-throughput

0.817

High

540566

SIF2
SIR4-interacting protein SIF2

7

3

Small-scale

0.744

High

540533

SNT1
Probable DNA-binding protein SNT1

6

2

Small-scale

0.729

High

540532

SIS1
Protein SIS1

2

0

High-throughput

0.716

High

540589

HOS4
Protein HOS4

5

3

Small-scale

0.712

High

540609

HOS2
Probable histone deacetylase HOS2

5

3

Small-scale

0.709

High

540560

SET3
SET domain-containing protein 3

5

5

Small-scale

0.699

High

540593

IST3
U2 snRNP component IST3

1

4

High-throughput

0.691

High

540664

HSH49
Protein HSH49

1

1

High-throughput

0.691

High

540660

RUVB2
RuvB-like protein 2

4

1

High-throughput

0.678

High

540658

SMT3
Ubiquitin-like protein SMT3

3

7

Small-scale

0.650

High

365705

HSP82
ATP-dependent molecular chaperone HSP82

3

11

High-throughput

0.640

High

356218

H4
Histone H4

3

1

High-throughput

0.634

High

540525

SNF2
Transcription regulatory protein SNF2

2

2

High-throughput

0.621

High

540656

PUF2
mRNA-binding protein PUF2

1

1

High-throughput

0.618

High

540598

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

540519

HSC82
ATP-dependent molecular chaperone HSC82

2

11

High-throughput

0.571

High

540577

KOG1
Target of rapamycin complex 1 subunit KOG1

2

2

High-throughput

0.571

High

540638

RUVB1
RuvB-like protein 1

2

1

High-throughput

0.571

High

420210

CALM
Calmodulin

2

3

High-throughput

0.567

High

493093

HSP72
Heat shock protein SSA2

2

12

High-throughput

0.552

High

540585

SSB2
Ribosome-associated molecular chaperone SSB2

2

10

High-throughput

0.552

High

540631

SDC1
COMPASS component SDC1

1

0

High-throughput

0.546

High

540531

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

1

High-throughput

0.536

High

540581

DUN1
DNA damage response protein kinase DUN1

1

2

High-throughput

0.536

High

540624

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

540597

BUD27
Bud site selection protein 27

1

0

Small-scale

0.518

High

540539

CGS5
S-phase entry cyclin-5

1

3

High-throughput

0.515

High

540546

RPD3
Histone deacetylase RPD3

1

5

Small-scale

0.515

High

540586

CCS1
Superoxide dismutase 1 copper chaperone

1

4

High-throughput

0.515

High

420428

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.513

High

540517

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.513

High

540527

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.513

High

540529

MPIP
M-phase inducer phosphatase

1

0

High-throughput

0.513

High

540535

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.513

High

540619

IGO1
mRNA stability protein IGO1

1

0

High-throughput

0.513

High

540648

BUD20
Bud site selection protein 20

1

0

High-throughput

0.513

High

355324

H2B1
Histone H2B.1

1

1

Small-scale

0.501

High

540544

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

0

High-throughput

0.493

High

540570

SAP30
Transcriptional regulatory protein SAP30

1

0

Small-scale

0.493

High

540615

HST1
NAD-dependent protein deacetylase HST1

1

0

Small-scale

0.493

High

540643

ECM38
Glutathione hydrolase proenzyme

1

0

High-throughput

0.493

High

540645

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.493

High

540653

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.493

High

540654

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.493

High

540580

TEM1
Protein TEM1

1

3

High-throughput

0.489

High

540600

BBC1
Myosin tail region-interacting protein MTI1

1

2

High-throughput

0.489

High

540591

ULP2
Ubiquitin-like-specific protease 2

1

3

High-throughput

0.481

High

540592

MPH1
ATP-dependent DNA helicase MPH1

1

11

Small-scale

0.481

High

540617

RHO5
GTP-binding protein RHO5

1

9

Small-scale

0.481

High

540627

ULP1
Ubiquitin-like-specific protease 1

1

3

High-throughput

0.481

High

334423

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.479

High

334880

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.479

High

339405

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.479

High

339992

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.479

High

340599

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.479

High

342638

ENO1
Enolase 1

1

3

High-throughput

0.479

High

342838

ENO2
Enolase 2

1

3

High-throughput

0.479

High

343516

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

381523

GAL4
Regulatory protein GAL4

1

1

Small-scale

0.479

High

472539

YD14B
Transposon Ty1-DR5 Gag-Pol polyprotein

1

7

High-throughput

0.479

High

472585

YL13B
Transposon Ty1-LR3 Gag-Pol polyprotein

1

7

High-throughput

0.479

High

540523

SFL1
Flocculation suppression protein

1

1

High-throughput

0.479

High

540528

TKT1
Transketolase 1

1

1

High-throughput

0.479

High

540534

YC21B
Transposon Ty2-C Gag-Pol polyprotein

1

8

High-throughput

0.479

High

540537

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

540538

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.479

High

540541

SWC3
SWR1-complex protein 3

1

1

High-throughput

0.479

High

540550

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

540552

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

540553

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

540554

IXR1
Intrastrand cross-link recognition protein

1

5

Small-scale

0.479

High

540555

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

540563

GBLP
Small ribosomal subunit protein RACK1

1

5

Small-scale

0.479

High

540568

SWC5
SWR1-complex protein 5

1

1

High-throughput

0.479

High

540574

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

6

Small-scale

0.479

High

540579

CH10
10 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

540601

YJ11B
Transposon Ty1-JR1 Gag-Pol polyprotein

1

7

High-throughput

0.479

High

540602

YJ12B
Transposon Ty1-JR2 Gag-Pol polyprotein

1

7

High-throughput

0.479

High

540621

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

540625

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

1

High-throughput

0.479

High

540626

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

540630

TOM1
E3 ubiquitin-protein ligase TOM1

1

7

High-throughput

0.479

High

540634

YM12B
Transposon Ty1-ML2 Gag-Pol polyprotein

1

7

High-throughput

0.479

High

540635

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

7

High-throughput

0.479

High

540637

GIS1
Transcriptional activator/repressor GIS1

1

2

High-throughput

0.479

High

540641

SWR1
Helicase SWR1

1

3

High-throughput

0.479

High

540647

PUF3
mRNA-binding protein PUF3

1

1

High-throughput

0.479

High

540655

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.479

High

540657

YB21A
Transposon Ty2-B Gag polyprotein

1

8

High-throughput

0.479

High

540661

YB11B
Transposon Ty1-BL Gag-Pol polyprotein

1

7

High-throughput

0.479

High

540662

ARP6
Actin-like protein ARP6

1

4

High-throughput

0.479

High

540605

CENPK
Inner kinetochore subunit MCM22

1

0

High-throughput

0.460

High

336188

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

Small-scale

0.458

High

343345

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

357849

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

375245

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

389210

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

410883

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

413269

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

421743

KAD2
Adenylate kinase

1

0

High-throughput

0.458

High

425726

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

470824

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

482046

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

520898

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

529987

STE12
Protein STE12

1

0

High-throughput

0.458

High

537338

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

540518

TAL1
Transaldolase

1

0

High-throughput

0.458

High

540521

TEC1
Ty transcription activator TEC1

1

0

High-throughput

0.458

High

540524

MSB1
Morphogenesis-related protein MSB1

1

0

High-throughput

0.458

High

540526

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

540540

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.458

High

540557

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

540567

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.458

High

540572

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

540573

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.458

High

540578

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

540582

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

540590

VHR1
Transcription factor VHR1

1

0

High-throughput

0.458

High

540604

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

540607

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.458

High

540608

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

540612

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

540614

DCP2
m7GpppN-mRNA hydrolase

1

0

Small-scale

0.458

High

540629

COFI
Cofilin

1

0

High-throughput

0.458

High

540632

VPS72
Vacuolar protein sorting-associated protein 72

1

0

High-throughput

0.458

High

540633

VPS71
Vacuolar protein sorting-associated protein 71

1

0

High-throughput

0.458

High

540639

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

540642

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

0

High-throughput

0.458

High

540644

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

540650

ZEO1
Protein ZEO1

1

0

High-throughput

0.458

High

336709

SODM
Superoxide dismutase [Mn], mitochondrial

1

1

High-throughput

0.445

High

367682

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

416751

CDC31
Cell division control protein 31

1

4

High-throughput

0.445

High

446100

MYO1
Myosin-1

1

2

High-throughput

0.445

High

490206

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

510122

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

526179

KIN2
Serine/threonine-protein kinase KIN2

1

2

High-throughput

0.445

High

540522

MYO2
Myosin-2

1

3

High-throughput

0.445

High

540543

SP110
Spindle pole body component 110

1

6

High-throughput

0.445

High

540545

MYO4
Myosin-4

1

3

High-throughput

0.445

High

540547

TOR2
Serine/threonine-protein kinase TOR2

1

3

High-throughput

0.445

High

540556

TOR1
Serine/threonine-protein kinase TOR1

1

3

High-throughput

0.445

High

540564

AKL1
Serine/threonine-protein kinase AKL1

1

2

High-throughput

0.445

High

540571

KSP1
Serine/threonine-protein kinase KSP1

1

4

High-throughput

0.445

High

540576

SPC97
Spindle pole body component SPC97

1

1

High-throughput

0.445

High

540583

RSP5
E3 ubiquitin-protein ligase RSP5

1

7

High-throughput

0.445

High

540584

BEM2
GTPase-activating protein BEM2/IPL2

1

2

High-throughput

0.445

High

540594

LST8
Target of rapamycin complex subunit LST8

1

3

High-throughput

0.445

High

540610

MLC1
Myosin light chain 1

1

3

High-throughput

0.445

High

540613

SPC98
Spindle pole body component SPC98

1

1

High-throughput

0.445

High

540616

CNM67
Chaotic nuclear migration protein 67

1

3

High-throughput

0.445

High

540618

CBK1
Serine/threonine-protein kinase CBK1

1

1

High-throughput

0.445

High

540622

ACT
Actin

1

3

High-throughput

0.445

High

540623

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.445

High

540646

BRE1
E3 ubiquitin-protein ligase BRE1

1

5

High-throughput

0.445

High

540561

VBA5
Vacuolar basic amino acid transporter 5

1

0

High-throughput

0.438

High

540562

VRP1
Verprolin

1

3

High-throughput

0.437

High

540652

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

519553

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.426

High

540520

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.426

High

540530

SSD1
Protein SSD1

1

0

High-throughput

0.426

High

540536

BUB2
Mitotic check point protein BUB2

1

0

High-throughput

0.426

High

540542

NUD1
Protein NUD1

1

0

High-throughput

0.426

High

540558

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.426

High

540559

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.426

High

540575

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.426

High

540587

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.426

High

540588

TAO3
Cell morphogenesis protein PAG1

1

0

High-throughput

0.426

High

540596

MOB2
CBK1 kinase activator protein MOB2

1

0

High-throughput

0.426

High

540603

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.426

High

540606

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.426

High

540628

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

540636

EFR3
Protein EFR3

1

0

High-throughput

0.426

High

540649

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.426

High

540651

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.426

High

540659

BBP1
Spindle pole component BBP1

1

0

High-throughput

0.426

High

540663

H2AZ
Histone H2A.Z

1

0

High-throughput

0.426

High

540548

CDC13
Cell division control protein 13

1

0

High-throughput

0.279

Low

540551

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.279

Low

540620

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.279

Low

540640

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

540549

SKG6
Protein SKG6

1

0

High-throughput

0.249

Low

540569

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

540565

NU170
Nucleoporin NUP170

1

0

High-throughput

0.232

Low

540595

COPB
Coatomer subunit beta

1

0

High-throughput

0.232

Low

540599

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low

540611

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024