Protein: IL4
Interleukin-4 (IL-4) (B-cell stimulatory factor 1) (BSF-1) (Binetrakin) (Lymphocyte stimulatory factor 1) (Pitrakinra)

Gene: IL4
Organism: Homo sapiens
Interactions: 19
UniProt ID: P05112

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005125 - cytokine activity
GO:0005136 - interleukin-4 receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

424316

IL4RA
Interleukin-4 receptor subunit alpha

10

3

Small-scale

0.973

High

424317

IL2RG
Cytokine receptor common subunit gamma

1

3

Small-scale

0.691

High

369581

A2MG
Alpha-2-macroglobulin

2

0

Small-scale

0.569

High

424319

I13R1
Interleukin-13 receptor subunit alpha-1

1

3

Small-scale

0.553

High

424311

IRF1
Interferon regulatory factor 1

1

3

Small-scale

0.515

High

424312

IRF2
Interferon regulatory factor 2

1

3

Small-scale

0.515

High

340806

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

2

Small-scale

0.479

High

424313

CEBPB
CCAAT/enhancer-binding protein beta

1

1

Small-scale

0.479

High

424314

EGR1
Early growth response protein 1

1

1

Small-scale

0.479

High

424315

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

1

Small-scale

0.479

High

424318

CEBPG
CCAAT/enhancer-binding protein gamma

1

1

Small-scale

0.479

High

424321

TF65
Transcription factor p65

1

2

Small-scale

0.479

High

424322

EGR3
Early growth response protein 3

1

1

Small-scale

0.479

High

424324

IRF4
Interferon regulatory factor 4

1

3

Small-scale

0.479

High

424310

MYB
Transcriptional activator Myb

1

0

Small-scale

0.458

High

424320

CREM
cAMP-responsive element modulator

1

0

Small-scale

0.458

High

424323

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.458

High

424325

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low

424309

CP2E1
Cytochrome P450 2E1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025