Protein: DEN2D
DENN domain-containing protein 2D

Gene: DEN2D, DENND2D
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q9H6A0

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

537913

HSP7C
Heat shock cognate 71 kDa protein

3

4

High-throughput

0.667

High

839921

AF9
Protein AF-9

3

1

High-throughput

0.667

High

1105092

TCOF
Treacle protein

3

1

High-throughput

0.667

High

1432353

PININ
Pinin

3

1

High-throughput

0.667

High

1434872

AFF4
AF4/FMR2 family member 4

3

1

High-throughput

0.667

High

674330

BRD2
Bromodomain-containing protein 2

3

0

High-throughput

0.638

High

709166

TPP2
Tripeptidyl-peptidase 2

3

0

High-throughput

0.638

High

936620

ELL
RNA polymerase II elongation factor ELL

3

0

High-throughput

0.638

High

1134536

NOLC1
Nucleolar and coiled-body phosphoprotein 1

3

0

High-throughput

0.638

High

1243774

FXL19
F-box/LRR-repeat protein 19

3

0

High-throughput

0.638

High

1329577

CA052
UPF0690 protein C1orf52

3

0

High-throughput

0.638

High

1364041

RTF1
RNA polymerase-associated protein RTF1 homolog

3

0

High-throughput

0.638

High

1434869

GRPE1
GrpE protein homolog 1, mitochondrial

3

0

High-throughput

0.638

High

1434870

CWC22
Pre-mRNA-splicing factor CWC22 homolog

3

0

High-throughput

0.638

High

1434871

E41L5
Band 4.1-like protein 5

3

0

High-throughput

0.638

High

1040757

ENL
Protein ENL

2

1

High-throughput

0.628

High

761881

HSP74
Heat shock 70 kDa protein 4

2

4

High-throughput

0.611

High

1145372

RNPS1
RNA-binding protein with serine-rich domain 1

2

1

High-throughput

0.611

High

801528

HSPA9
Stress-70 protein, mitochondrial

3

5

High-throughput

0.609

High

396944

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

1316990

FAM9B
Protein FAM9B

1

0

High-throughput

0.549

High

347933

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.536

High

1434873

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

3

High-throughput

0.536

High

1292621

GPBP1
Vasculin

1

0

High-throughput

0.513

High

1434874

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.513

High

987475

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.493

High

761516

HS71L
Heat shock 70 kDa protein 1-like

1

4

High-throughput

0.479

High

800105

COIL
Coilin

1

0

High-throughput

0.458

High

1358662

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

0

High-throughput

0.251

Low

1413982

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025