Protein: RTF1
RNA polymerase-associated protein RTF1 homolog

Gene: RTF1
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q92541

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001711 - endodermal cell fate commitment
GO:0001832 - blastocyst growth
GO:0003697 - single-stranded DNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1330547

PAF1
RNA polymerase II-associated factor 1 homolog

5

2

Small-scale

0.709

High

882540

ARRB1
Beta-arrestin-1

3

1

High-throughput

0.671

High

871989

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

1

High-throughput

0.662

High

1243837

CTR9
RNA polymerase-associated protein CTR9 homolog

3

2

Small-scale

0.650

High

1357902

LEO1
RNA polymerase-associated protein LEO1

3

2

Small-scale

0.650

High

1364041

DEN2D
DENN domain-containing protein 2D

3

0

High-throughput

0.638

High

732660

ARRB2
Beta-arrestin-2

2

1

High-throughput

0.628

High

625529

CSK22
Casein kinase II subunit alpha'

2

5

High-throughput

0.611

High

997900

CSK21
Casein kinase II subunit alpha

2

4

High-throughput

0.611

High

1240669

CDC73
Parafibromin

2

1

Small-scale

0.601

High

242453

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

558296

XRCC6
X-ray repair cross-complementing protein 6

2

0

High-throughput

0.559

High

861704

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.554

High

1006600

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.550

High

1331829

SYT2
Synaptotagmin-2

2

1

High-throughput

0.549

High

1349203

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

1

High-throughput

0.536

High

1163101

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.515

High

276496

PDCD6
Programmed cell death protein 6

1

0

High-throughput

0.513

High

848691

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

1364032

HS105
Heat shock protein 105 kDa

1

0

High-throughput

0.513

High

1364040

SKI8
Superkiller complex protein 8

1

0

Small-scale

0.513

High

654663

TCEA1
Transcription elongation factor A protein 1

1

0

Small-scale

0.494

High

961199

FGF12
Fibroblast growth factor 12

1

1

High-throughput

0.489

High

1364036

H2AJ
Histone H2A.J

1

1

High-throughput

0.489

High

508359

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

608317

EGLN
Endoglin

1

0

High-throughput

0.480

High

130559

SPT5H
Transcription elongation factor SPT5

1

2

High-throughput

0.479

High

260231

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

262550

MCE1
mRNA-capping enzyme

1

1

High-throughput

0.479

High

386040

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

443460

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.479

High

487588

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

565989

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

674273

BRD2
Bromodomain-containing protein 2

1

4

High-throughput

0.479

High

711168

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

1

Small-scale

0.479

High

883637

CENPA
Histone H3-like centromeric protein A

1

1

High-throughput

0.479

High

980969

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

1053713

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

1

Small-scale

0.479

High

1067551

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1128073

DHX8
ATP-dependent RNA helicase DHX8

1

1

High-throughput

0.479

High

1138447

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1311818

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.479

High

1337824

CSK23
Casein kinase II subunit alpha 3

1

4

High-throughput

0.479

High

1364037

DDX23
Probable ATP-dependent RNA helicase DDX23

1

2

High-throughput

0.479

High

1364044

DNM3B
DNA

1

1

Small-scale

0.479

High

1364049

DNM3A
DNA

1

1

Small-scale

0.479

High

141027

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

191023

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

224145

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

0

High-throughput

0.458

High

372709

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

606952

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

697199

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

768770

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

800013

COIL
Coilin

1

0

High-throughput

0.458

High

935934

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.458

High

979102

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

984880

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

986600

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1054749

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

1097453

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1364031

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1364033

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.458

High

1364035

SMRC1
SWI/SNF complex subunit SMARCC1

1

0

High-throughput

0.458

High

1364038

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.458

High

1364039

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

1364043

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1364045

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1364047

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.458

High

1364048

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

667383

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.445

High

884377

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

2

Small-scale

0.445

High

990978

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

2

Small-scale

0.445

High

970855

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1364034

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.437

High

639154

SYT1
Synaptotagmin-1

1

1

High-throughput

0.407

High

422749

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.314

High

347214

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

931032

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.279

Low

1016358

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.279

Low

1325064

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.279

Low

1364042

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

0

High-throughput

0.279

Low

1364046

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.279

Low

412349

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

703966

DUS1
Dual specificity protein phosphatase 1

1

0

Small-scale

0.249

Low

829481

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

948895

CD81
CD81 antigen

1

0

High-throughput

0.249

Low

995731

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

1042654

UPAR
Urokinase plasminogen activator surface receptor

1

0

Small-scale

0.249

Low

1087677

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

0

High-throughput

0.249

Low

1254859

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1276560

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1324509

FA43A
Protein FAM43A

1

0

Small-scale

0.249

Low

1338301

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1054129

BTK
Tyrosine-protein kinase BTK

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025