Protein: T2EA
Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (Factor A 66 kDa subunit) (Transcription factor A large subunit)

Gene: T2EA, TFA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P36100

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0001113 - transcription open complex formation at RNA polymerase II promoter
GO:0005634 - nucleus
GO:0005673 - transcription factor TFIIE complex
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

781045

T2EB
Transcription initiation factor IIE subunit beta

9

6

Small-scale

0.969

High

401969

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

1

Small-scale

0.834

High

706787

TF2B
Transcription initiation factor IIB

2

1

Small-scale

0.754

High

744603

TFB1
General transcription and DNA repair factor IIH subunit TFB1

5

2

Small-scale

0.715

High

624897

MED15
Mediator of RNA polymerase II transcription subunit 15

4

0

Small-scale

0.669

High

781060

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

2

2

Small-scale

0.585

High

594316

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.559

High

781062

TFB3
RNA polymerase II transcription factor B subunit 3

1

0

Small-scale

0.546

High

436381

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.515

High

781065

RCO1
Transcriptional regulatory protein RCO1

1

1

High-throughput

0.515

High

781055

T2FB
Transcription initiation factor IIF subunit beta

1

1

Small-scale

0.501

High

660845

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

0

High-throughput

0.493

High

666436

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.493

High

740490

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.493

High

781048

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

781051

IMB4
Importin subunit beta-4

1

0

High-throughput

0.493

High

781057

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.493

High

781063

PPN1
Endopolyphosphatase

1

0

High-throughput

0.493

High

781072

H2AZ
Histone H2A.Z

1

0

High-throughput

0.493

High

781047

CDC27
Anaphase-promoting complex subunit CDC27

1

1

High-throughput

0.489

High

547784

NHP6A
Non-histone chromosomal protein 6A

1

1

Small-scale

0.481

High

547866

NHP6B
Non-histone chromosomal protein 6B

1

1

Small-scale

0.481

High

699948

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

Small-scale

0.481

High

470509

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.480

High

757318

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

Small-scale

0.458

High

781053

GPX3
Glutathione peroxidase-like peroxiredoxin HYR1

1

0

Small-scale

0.458

High

781071

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

440839

KIN28
Serine/threonine-protein kinase KIN28

1

1

Small-scale

0.445

High

449332

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD/RAD3

1

1

Small-scale

0.445

High

523614

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526403

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544472

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

726935

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741359

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

752125

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

781052

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

781061

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

1

Small-scale

0.445

High

781064

SSL1
General transcription and DNA repair factor IIH subunit SSL1

1

1

Small-scale

0.445

High

781066

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

2

High-throughput

0.445

High

781069

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

1

Small-scale

0.445

High

381068

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

671619

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

781046

CCL1
Cyclin CCL1

1

0

Small-scale

0.426

High

781049

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

781054

T2FA
Transcription initiation factor IIF subunit alpha

1

0

Small-scale

0.426

High

781068

TFB6
General transcription and DNA repair factor IIH subunit TFB6

1

0

Small-scale

0.426

High

781073

TFB5
General transcription and DNA repair factor IIH subunit TFB5

1

0

Small-scale

0.426

High

781059

TMA20
Translation machinery-associated protein 20

2

0

High-throughput

0.324

High

739599

SPT16
FACT complex subunit SPT16

1

0

Small-scale

0.292

High

781058

ZNG1
Zinc-regulated GTPase metalloprotein activator 1

1

0

High-throughput

0.279

Low

703767

CAPZA
F-actin-capping protein subunit alpha

1

0

High-throughput

0.269

Low

781050

FLC2
Flavin carrier protein 2

1

0

High-throughput

0.269

Low

781056

CWP2
Cell wall protein CWP2

1

0

High-throughput

0.269

Low

753062

NIP80
Protein NIP100

1

0

High-throughput

0.251

Low

781070

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

781067

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025