Protein: JEM1
DnaJ-like chaperone JEM1 (DnaJ-like protein of the ER membrane 1)

Gene: JEM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P40358

Gene Ontology (top 5):
GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0031965 - nuclear membrane
GO:0034975 - protein folding in endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

560680

BIP
Endoplasmic reticulum chaperone BiP

2

20

Small-scale

0.812

High

491414

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.618

High

511543

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.618

High

772553

JEM1
DnaJ-like chaperone JEM1

1

18

High-throughput

0.618

High

772556

EPS1
ER-retained PMA1-suppressing protein 1

1

20

High-throughput

0.575

High

772561

TOS3
Serine/threonine-protein kinase TOS3

1

2

High-throughput

0.514

High

691633

NUP2
Nucleoporin NUP2

1

4

High-throughput

0.445

High

745690

NU170
Nucleoporin NUP170

1

3

High-throughput

0.445

High

753836

RPN1
26S proteasome regulatory subunit RPN1

1

7

High-throughput

0.445

High

772567

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

High-throughput

0.445

High

772571

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

1

High-throughput

0.445

High

772578

UFD2
E4 ubiquitin-protein ligase UFD2

1

11

High-throughput

0.445

High

415998

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.437

High

662400

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

664867

BMH1
Protein BMH1

1

2

High-throughput

0.437

High

772577

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.437

High

772588

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

763282

PO152
Nucleoporin POM152

1

0

High-throughput

0.426

High

763500

NUP60
Nucleoporin NUP60

1

0

High-throughput

0.426

High

772576

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

772600

SEC39
Protein transport protein SEC39

1

0

High-throughput

0.426

High

429710

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.407

High

523278

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

8

High-throughput

0.407

High

539474

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

4

High-throughput

0.407

High

562241

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

4

High-throughput

0.407

High

562397

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

4

High-throughput

0.407

High

571899

SKI3
Superkiller protein 3

1

17

High-throughput

0.407

High

593649

DBP4
ATP-dependent RNA helicase HCA4

1

6

High-throughput

0.407

High

599183

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

3

High-throughput

0.407

High

607283

RFA1
Replication factor A protein 1

1

5

High-throughput

0.407

High

608702

UBA1
Ubiquitin-activating enzyme E1 1

1

2

High-throughput

0.407

High

634247

GID7
Glucose-induced degradation protein 7

1

8

High-throughput

0.407

High

635783

IMG2
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

644761

RFA2
Replication factor A protein 2

1

3

High-throughput

0.407

High

655566

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

2

High-throughput

0.407

High

686891

P5CR
Pyrroline-5-carboxylate reductase

1

5

High-throughput

0.407

High

688124

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

1

High-throughput

0.407

High

690368

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

3

High-throughput

0.407

High

692807

SPT16
FACT complex subunit SPT16

1

3

High-throughput

0.407

High

700044

PREP
Presequence protease, mitochondrial

1

3

High-throughput

0.407

High

706146

MFT1
THO complex subunit MFT1

1

1

High-throughput

0.407

High

730638

EF1G2
Elongation factor 1-gamma 2

1

2

High-throughput

0.407

High

732148

CAB3
Coenzyme A biosynthesis protein 3

1

1

High-throughput

0.407

High

748536

ARPC1
Actin-related protein 2/3 complex subunit 1

1

9

High-throughput

0.407

High

753521

YLF2
Obg-like ATPase homolog

1

1

High-throughput

0.407

High

758965

SHC1
Protein SHC1

1

3

High-throughput

0.407

High

762758

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

4

High-throughput

0.407

High

767781

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.407

High

772554

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

3

High-throughput

0.407

High

772558

SA185
SIT4-associating protein SAP185

1

2

High-throughput

0.407

High

772559

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.407

High

772566

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.407

High

772569

PESC
Pescadillo homolog

1

3

High-throughput

0.407

High

772570

COPA
Coatomer subunit alpha

1

8

High-throughput

0.407

High

772572

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.407

High

772579

H3
Histone H3

1

7

High-throughput

0.407

High

772580

PURA
Adenylosuccinate synthetase

1

1

High-throughput

0.407

High

772581

NAM8
Protein NAM8

1

1

High-throughput

0.407

High

772582

NOP3
Serine/arginine

1

1

High-throughput

0.407

High

772584

CWC21
Pre-mRNA-splicing factor CWC21

1

1

High-throughput

0.407

High

772586

RRP5
rRNA biogenesis protein RRP5

1

3

High-throughput

0.407

High

772587

ELP1
Elongator complex protein 1

1

1

High-throughput

0.407

High

772589

FRA1
Putative Xaa-Pro aminopeptidase FRA1

1

1

High-throughput

0.407

High

772590

NOC3
Nucleolar complex-associated protein 3

1

3

High-throughput

0.407

High

772593

ARP8
Actin-like protein ARP8

1

2

High-throughput

0.407

High

772594

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

3

High-throughput

0.407

High

772595

PRP46
Pre-mRNA-splicing factor PRP46

1

8

High-throughput

0.407

High

772596

NSI1
RNA polymerase I termination factor

1

2

High-throughput

0.407

High

772597

NOP56
Nucleolar protein 56

1

3

High-throughput

0.407

High

772598

NOP58
Nucleolar protein 58

1

3

High-throughput

0.407

High

772564

MPS3
Spindle pole body assembly component MPS3

2

0

Small-scale

0.323

High

479755

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

523396

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.249

Low

772592

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

340688

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

341717

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.232

Low

419555

RAD1
DNA repair protein RAD1

1

0

High-throughput

0.232

Low

450451

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.232

Low

521138

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.232

Low

568884

HPR1
THO complex subunit HPR1

1

0

High-throughput

0.232

Low

689889

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low

693928

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.232

Low

699347

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.232

Low

699824

PDC2
Protein PDC2

1

0

High-throughput

0.232

Low

700773

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.232

Low

715879

MAC1
Metal-binding activator 1

1

0

High-throughput

0.232

Low

730424

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.232

Low

742717

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.232

Low

764001

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.232

Low

768223

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

0

High-throughput

0.232

Low

770126

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

0

High-throughput

0.232

Low

772555

YIF8
Putative uncharacterized protein YIL058W

1

0

High-throughput

0.232

Low

772557

EGH1
Ergosteryl-beta-glucosidase

1

0

High-throughput

0.232

Low

772560

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.232

Low

772562

MTHR1
Methylenetetrahydrofolate reductase 1

1

0

High-throughput

0.232

Low

772563

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.232

Low

772565

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.232

Low

772568

ORC5
Origin recognition complex subunit 5

1

0

High-throughput

0.232

Low

772573

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.232

Low

772574

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.232

Low

772575

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.232

Low

772583

SGF11
SAGA-associated factor 11

1

0

High-throughput

0.232

Low

772585

RAD33
DNA repair protein RAD33

1

0

High-throughput

0.232

Low

772591

TMC1
AN1-type zinc finger protein TMC1

1

0

High-throughput

0.232

Low

772599

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024