Protein: SLX4
Structure-specific endonuclease subunit SLX4 (Synthetic lethal of unknown function protein 4)

Gene: SLX4
Organism: Saccharomyces cerevisiae S288C
Interactions: 33
UniProt ID: Q12098

Gene Ontology (top 5):
GO:0000228 - nuclear chromosome
GO:0000727 - double-strand break repair via break-induced replication
GO:0000736 - double-strand break repair via single-strand annealing, removal of nonhomologous ends
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

798088

SLX1
Structure-specific endonuclease subunit SLX1

13

0

Small-scale

0.930

High

805995

RT107
Regulator of Ty1 transposition protein 107

11

0

Small-scale

0.729

High

448416

RAD1
DNA repair protein RAD1

7

0

Small-scale

0.719

High

864256

DPB11
DNA replication regulator DPB11

6

0

Small-scale

0.707

High

804546

SSZ1
Ribosome-associated complex subunit SSZ1

2

0

High-throughput

0.563

High

796778

MMS4
Crossover junction endonuclease MMS4

2

0

Small-scale

0.559

High

672033

MSH3
DNA mismatch repair protein MSH3

1

1

Small-scale

0.552

High

682948

MSH2
DNA mismatch repair protein MSH2

1

1

Small-scale

0.552

High

1045070

MUS81
Crossover junction endonuclease MUS81

1

0

Small-scale

0.529

High

449291

RAD10
DNA repair protein RAD10

1

0

Small-scale

0.513

High

814153

SAW1
Single-strand annealing weakened protein 1

1

0

Small-scale

0.504

High

416487

HXKA
Hexokinase-1

1

0

High-throughput

0.493

High

576020

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.493

High

760376

BMH2
Protein BMH2

1

0

High-throughput

0.493

High

792377

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.493

High

858145

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

364801

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

792490

CDC27
Anaphase-promoting complex subunit CDC27

1

0

High-throughput

0.460

High

646563

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

708486

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

781970

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

865780

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

1062332

SMC5
Structural maintenance of chromosomes protein 5

1

0

Small-scale

0.458

High

1065521

DDC1
DNA damage checkpoint protein 1

1

0

Small-scale

0.458

High

546674

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742635

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

820076

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

1084298

PSF1
DNA replication complex GINS protein PSF1

1

0

High-throughput

0.438

High

525483

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

816466

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

824582

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

359541

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

0

High-throughput

0.269

Low

597578

EF3A
Elongation factor 3A

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025