Protein: PSF1
DNA replication complex GINS protein PSF1 (Partner of Sld five 1)

Gene: PSF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: Q12488

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000811 - GINS complex
GO:0005634 - nucleus
GO:0006261 - DNA-templated DNA replication
GO:0031261 - DNA replication preinitiation complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042688

SLD5
DNA replication complex GINS protein SLD5

23

4

Small-scale

0.990

High

721436

MCM4
DNA replication licensing factor MCM4

15

12

Small-scale

0.981

High

1030414

CTF4
DNA polymerase alpha-binding protein

7

2

Small-scale

0.965

High

713063

MCM2
DNA replication licensing factor MCM2

9

11

Small-scale

0.964

High

823323

PSF2
DNA replication complex GINS protein PSF2

7

5

Small-scale

0.961

High

664479

MCM3
DNA replication licensing factor MCM3

7

11

Small-scale

0.957

High

1061506

CDC45
Cell division control protein 45

6

3

Small-scale

0.936

High

864258

DPB11
DNA replication regulator DPB11

4

1

Small-scale

0.901

High

917081

MCM6
DNA replication licensing factor MCM6

4

11

Small-scale

0.885

High

794108

MCM7
DNA replication licensing factor MCM7

4

11

Small-scale

0.882

High

713318

MCM5
Minichromosome maintenance protein 5

4

12

Small-scale

0.878

High

1084410

PSF3
DNA replication complex GINS protein PSF3

3

3

Small-scale

0.840

High

665216

DPB2
DNA polymerase epsilon subunit B

7

2

Small-scale

0.747

High

561337

DPOLA
DNA polymerase alpha catalytic subunit A

4

2

Small-scale

0.633

High

917535

SLD3
DNA replication regulator SLD3

3

0

Small-scale

0.621

High

735418

MCM10
Minichromosome maintenance protein 10

2

2

Small-scale

0.619

High

1084986

PSF1
DNA replication complex GINS protein PSF1

1

0

Small-scale

0.589

High

758518

SLD2
DNA replication regulator SLD2

2

0

Small-scale

0.559

High

1054022

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

2

0

High-throughput

0.551

High

642085

DPOE
DNA polymerase epsilon catalytic subunit A

1

2

Small-scale

0.501

High

647867

RFA1
Replication factor A protein 1

1

1

Small-scale

0.479

High

739832

SPT16
FACT complex subunit SPT16

1

1

Small-scale

0.479

High

586498

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

708617

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

793838

DPOA2
DNA polymerase alpha subunit B

1

0

Small-scale

0.458

High

803761

RRM3
ATP-dependent DNA helicase RRM3

1

0

Small-scale

0.458

High

805536

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.458

High

916759

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.458

High

1025204

SEN1
Helicase SEN1

1

0

Small-scale

0.458

High

1064370

DIA2
Protein DIA2

1

0

Small-scale

0.458

High

625153

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.438

High

678768

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.438

High

764180

SPT21
Protein SPT21

1

0

High-throughput

0.438

High

792691

RIB1
GTP cyclohydrolase-2

1

0

High-throughput

0.438

High

817553

YEQ9
Uncharacterized protein YER079W

1

0

High-throughput

0.438

High

825867

VHR1
Transcription factor VHR1

1

0

High-throughput

0.438

High

835097

HAC1
Transcriptional activator HAC1

1

0

High-throughput

0.438

High

1037088

HAP5
Transcriptional activator HAP5

1

0

High-throughput

0.438

High

1084298

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.438

High

1084533

YRR1
Zinc finger transcription factor YRR1

1

0

High-throughput

0.438

High

793879

DTR1
Dityrosine transporter 1

1

1

High-throughput

0.417

High

1060324

TPO1
Polyamine transporter 1

1

1

High-throughput

0.417

High

646282

SEC22
Protein transport protein SEC22

1

0

High-throughput

0.238

Low

699380

ERV1
Mitochondrial FAD-linked sulfhydryl oxidase ERV1

1

0

High-throughput

0.238

Low

740506

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.238

Low

805478

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.238

Low

816945

RRAAH
4-hydroxy-4-methyl-2-oxoglutarate aldolase

1

0

High-throughput

0.238

Low

817525

YEQ6
Putative uncharacterized protein YER076C

1

0

High-throughput

0.238

Low

1055787

MLC2
Myosin light chain 2

1

0

High-throughput

0.238

Low

752921

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025