Protein: MMS4
Crossover junction endonuclease MMS4 (EC 3.1.22.-)

Gene: MMS4
Organism: Saccharomyces cerevisiae S288C
Interactions: 28
UniProt ID: P38257

Gene Ontology (top 5):
GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0004519 - endonuclease activity
GO:0005634 - nucleus
GO:0006265 - DNA topological change

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796776

MUS81
Crossover junction endonuclease MUS81

15

0

Small-scale

0.934

High

739952

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

4

0

Small-scale

0.665

High

796773

DPB11
DNA replication regulator DPB11

3

0

Small-scale

0.646

High

796768

RT107
Regulator of Ty1 transposition protein 107

3

0

Small-scale

0.613

High

364495

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.603

High

796778

SLX4
Structure-specific endonuclease subunit SLX4

2

0

Small-scale

0.559

High

796767

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

0

Small-scale

0.537

High

796777

ESC2
Protein ESC2

1

0

Small-scale

0.537

High

796774

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.513

High

796775

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

796769

RFC4
Replication factor C subunit 4

1

1

Small-scale

0.501

High

796770

RFC2
Replication factor C subunit 2

1

1

Small-scale

0.501

High

744995

YSC84
Protein YSC84

1

1

High-throughput

0.494

High

796772

LSB3
LAS seventeen-binding protein 3

1

1

High-throughput

0.494

High

448445

RAD52
DNA repair and recombination protein RAD52

1

0

Small-scale

0.480

High

586452

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.480

High

440930

CDC7
Cell division control protein 7

1

1

Small-scale

0.479

High

666174

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

Small-scale

0.460

High

689755

FEN1
Flap endonuclease 1

1

0

Small-scale

0.458

High

734255

DBF4
DDK kinase regulatory subunit DBF4

1

0

Small-scale

0.458

High

796771

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

741453

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

744837

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.438

High

523746

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

544645

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

367009

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.261

Low

425122

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.261

Low

510431

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025