Protein: RL35A
Large ribosomal subunit protein uL29A (60S ribosomal protein L35-A)

Gene: RL35A, RPL35A
Organism: Saccharomyces cerevisiae S288C
Interactions: 203
UniProt ID: P0CX84

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 - cytoplasmic translation
GO:0003729 - mRNA binding
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

409875

RL25
Large ribosomal subunit protein uL23

2

2

High-throughput

0.754

High

515252

SSF1
Ribosome biogenesis protein SSF1

6

1

Small-scale

0.721

High

515317

ARX1
Probable metalloprotease ARX1

6

2

Small-scale

0.719

High

515286

LSG1
Large subunit GTPase 1

5

2

Small-scale

0.702

High

515256

RIX1
Pre-rRNA-processing protein RIX1

5

0

Small-scale

0.672

High

515241

RPF2
Ribosome biogenesis protein RPF2

3

2

Small-scale

0.650

High

515200

SSB1
Ribosome-associated molecular chaperone SSB1

3

2

Small-scale

0.640

High

515221

RL16A
Large ribosomal subunit protein uL13A

3

3

Small-scale

0.640

High

515197

SSBP1
Single-stranded nucleic acid-binding protein

2

2

High-throughput

0.595

High

509861

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

2

4

Small-scale

0.584

High

515216

SRO9
RNA-binding protein SRO9

2

4

Small-scale

0.584

High

515231

ZUO1
Zuotin

2

1

Small-scale

0.584

High

515258

DHH1
ATP-dependent RNA helicase DHH1

2

3

Small-scale

0.584

High

515273

RL10
Large ribosomal subunit protein uL16

2

1

Small-scale

0.584

High

515282

RL37A
Large ribosomal subunit protein eL37A

2

2

High-throughput

0.584

High

515314

RLI1
Translation initiation factor RLI1

2

1

Small-scale

0.584

High

515345

RL7B
Large ribosomal subunit protein uL30B

2

4

High-throughput

0.584

High

515350

RL13A
Large ribosomal subunit protein eL13A

2

1

Small-scale

0.584

High

515213

SIS1
Protein SIS1

2

0

High-throughput

0.576

High

515227

HS104
Heat shock protein 104

2

0

High-throughput

0.559

High

515254

NMD3
60S ribosomal export protein NMD3

2

0

Small-scale

0.559

High

515338

TMA46
Translation machinery-associated protein 46

2

0

High-throughput

0.559

High

515353

MEX67
mRNA export factor MEX67

2

0

Small-scale

0.559

High

515255

NACA
Nascent polypeptide-associated complex subunit alpha

2

1

Small-scale

0.533

High

149527

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

154124

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.479

High

383067

RLA4
Large ribosomal subunit protein P2B

1

2

High-throughput

0.479

High

383459

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

392090

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

427097

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.479

High

427530

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.479

High

427649

RLA2
Large ribosomal subunit protein P2A

1

2

High-throughput

0.479

High

432459

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.479

High

433127

RL17A
Large ribosomal subunit protein uL22A

1

2

High-throughput

0.479

High

433384

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.479

High

433955

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

434501

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.479

High

434739

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

435710

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

436292

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

4

High-throughput

0.479

High

441645

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

454810

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

502784

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

503344

RL11A
Large ribosomal subunit protein uL5A

1

2

High-throughput

0.479

High

503738

RL27A
Large ribosomal subunit protein eL27A

1

2

High-throughput

0.479

High

503884

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

503981

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

512197

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

512756

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

513442

RL1A
Large ribosomal subunit protein uL1A

1

3

High-throughput

0.479

High

513611

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.479

High

513936

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

514394

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

515026

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

515198

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.479

High

515199

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.479

High

515203

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

515204

SYKC
Lysine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

515205

RL8A
Large ribosomal subunit protein eL8A

1

2

High-throughput

0.479

High

515206

DBP5
ATP-dependent RNA helicase DBP5

1

1

Small-scale

0.479

High

515210

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.479

High

515215

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

515219

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

515220

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

515222

RL16B
Large ribosomal subunit protein uL13B

1

3

Small-scale

0.479

High

515223

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

515226

RL8B
Large ribosomal subunit protein eL8B

1

2

High-throughput

0.479

High

515228

EF2
Elongation factor 2

1

1

Small-scale

0.479

High

515237

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

515243

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.479

High

515248

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

515249

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

515251

CIC1
Proteasome-interacting protein CIC1

1

1

High-throughput

0.479

High

515260

RBG1
Ribosome-interacting GTPase 1

1

2

High-throughput

0.479

High

515262

NOC2
Nucleolar complex protein 2

1

1

High-throughput

0.479

High

515267

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.479

High

515270

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

515272

RL33B
Large ribosomal subunit protein eL33B

1

2

High-throughput

0.479

High

515276

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

515278

RL17B
Large ribosomal subunit protein uL22B

1

2

High-throughput

0.479

High

515280

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

515284

RL37B
Large ribosomal subunit protein eL37B

1

2

High-throughput

0.479

High

515285

NSA1
Ribosome biogenesis protein NSA1

1

1

Small-scale

0.479

High

515287

RL26B
Large ribosomal subunit protein uL24B

1

3

High-throughput

0.479

High

515296

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.479

High

515297

NOG2
Nucleolar GTP-binding protein 2

1

2

Small-scale

0.479

High

515298

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.479

High

515299

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.479

High

515300

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.479

High

515305

RL22B
Large ribosomal subunit protein eL22B

1

1

High-throughput

0.479

High

515306

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.479

High

515307

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.479

High

515308

NOP3
Serine/arginine

1

3

High-throughput

0.479

High

515309

MAP1
Methionine aminopeptidase 1

1

2

Small-scale

0.479

High

515310

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

515316

HAS1
ATP-dependent RNA helicase HAS1

1

5

High-throughput

0.479

High

515320

HMO1
High mobility group protein 1

1

1

High-throughput

0.479

High

515327

MRD1
Multiple RNA-binding domain-containing protein 1

1

3

High-throughput

0.479

High

515328

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

515331

RIX7
Ribosome biogenesis ATPase RIX7

1

2

High-throughput

0.479

High

515336

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

515340

YTM1
Ribosome biogenesis protein YTM1

1

2

Small-scale

0.479

High

515341

SLF1
Protein SLF1

1

4

Small-scale

0.479

High

515344

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.479

High

515347

DBP10
ATP-dependent RNA helicase DBP10

1

6

High-throughput

0.479

High

515352

RL11B
Large ribosomal subunit protein uL5B

1

2

High-throughput

0.479

High

414980

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

432784

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.458

High

438588

SC160
Protein SCP160

1

0

High-throughput

0.458

High

454328

PHO2
Regulatory protein PHO2

1

0

High-throughput

0.458

High

481952

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

511118

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.458

High

511360

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.458

High

511897

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.458

High

514217

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.458

High

515196

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.458

High

515211

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

515218

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

Small-scale

0.458

High

515235

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

515236

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

515238

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

515239

EAP1
Protein EAP1

1

0

High-throughput

0.458

High

515240

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

515244

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

515245

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

515257

RPN10
26S proteasome regulatory subunit RPN10

1

0

Small-scale

0.458

High

515259

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

515261

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

515271

NOP2
25S rRNA

1

0

Small-scale

0.458

High

515277

SCD6
Protein SCD6

1

0

High-throughput

0.458

High

515283

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

515288

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

515290

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

515291

ASCC3
RQC trigger complex helicase SLH1

1

0

High-throughput

0.458

High

515294

NRD1
Protein NRD1

1

0

High-throughput

0.458

High

515295

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

515312

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.458

High

515324

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

515325

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

515329

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

515346

MDY2
Ubiquitin-like protein MDY2

1

0

Small-scale

0.458

High

515349

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.458

High

515253

RPF1
Ribosome production factor 1

1

1

High-throughput

0.445

High

515265

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

515311

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

2

Small-scale

0.445

High

515342

NOP53
Ribosome biogenesis protein NOP53

1

1

Small-scale

0.445

High

364270

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.437

High

515207

PWP1
Periodic tryptophan protein 1

1

2

High-throughput

0.437

High

515208

SNF2
Transcription regulatory protein SNF2

1

3

High-throughput

0.437

High

515212

NAP1
Nucleosome assembly protein

1

2

High-throughput

0.437

High

515214

NLE1
Ribosome assembly protein 4

1

1

Small-scale

0.437

High

515217

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

515224

URA7
CTP synthase 1

1

1

High-throughput

0.437

High

515232

RPD3
Histone deacetylase RPD3

1

2

High-throughput

0.437

High

515233

CHD1
Chromo domain-containing protein 1

1

2

High-throughput

0.437

High

515250

ECM29
Proteasome component ECM29

1

3

High-throughput

0.437

High

515274

ELP2
Elongator complex protein 2

1

2

High-throughput

0.437

High

515301

NST1
Stress response protein NST1

1

1

High-throughput

0.437

High

515303

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

515315

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

515319

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

515323

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.437

High

515348

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

515201

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.305

High

515269

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

515326

RQC1
Ribosome quality control complex subunit 1

2

0

Small-scale

0.305

High

515268

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.251

Low

453880

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.249

Low

454377

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.249

Low

456491

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

0

Small-scale

0.249

Low

515202

ACOX
Acyl-coenzyme A oxidase

1

0

High-throughput

0.249

Low

515209

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.249

Low

515225

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

515229

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.249

Low

515230

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

515234

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.249

Low

515242

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

515246

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.249

Low

515247

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.249

Low

515263

ARB1
ABC transporter ATP-binding protein ARB1

1

0

Small-scale

0.249

Low

515264

YEN1
Holliday junction resolvase YEN1

1

0

High-throughput

0.249

Low

515266

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

515275

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

515279

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

515281

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

515289

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

515292

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.249

Low

515293

H1
Histone H1

1

0

High-throughput

0.249

Low

515302

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

515304

ERG13
Hydroxymethylglutaryl-CoA synthase

1

0

High-throughput

0.249

Low

515313

ELP4
Elongator complex protein 4

1

0

High-throughput

0.249

Low

515318

FIN1
Filament protein FIN1

1

0

Small-scale

0.249

Low

515321

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.249

Low

515322

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.249

Low

515330

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

515332

CMS1
Protein CMS1

1

0

High-throughput

0.249

Low

515333

SDO1
Ribosome maturation protein SDO1

1

0

High-throughput

0.249

Low

515334

ETT1
Enhancer of translation termination 1

1

0

High-throughput

0.249

Low

515335

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

515337

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

515339

TRMB
tRNA

1

0

High-throughput

0.249

Low

515343

HOSM
Homocitrate synthase, mitochondrial

1

0

High-throughput

0.249

Low

515351

EFG1P
rRNA-processing protein EFG1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025