Protein: FIR1
Factor interacting with REF2 (PAP1-interacting protein) (Polymerase-interacting protein 1)

Gene: FIR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P40020

Gene Ontology (top 5):
GO:0005935 - cellular bud neck
GO:0006397 - mRNA processing
GO:0032465 - regulation of cytokinesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817216

CBK1
Serine/threonine-protein kinase CBK1

4

0

Small-scale

0.669

High

364558

CDK1
Cyclin-dependent kinase 1

4

0

Small-scale

0.668

High

792404

BOI1
BEM1-interacting protein 1

3

1

Small-scale

0.667

High

816022

BOI2
BEM1-interacting protein 2

3

1

Small-scale

0.667

High

817223

CYK2
Cytokinesis protein 2

2

2

Small-scale

0.613

High

694206

BUD14
Bud site selection protein 14

2

0

Small-scale

0.587

High

654722

SPA2
Protein SPA2

1

0

Small-scale

0.504

High

757940

SKT5
Chitin synthase regulator SKT5

1

0

Small-scale

0.504

High

805394

BZZ1
Protein BZZ1

1

0

High-throughput

0.486

High

667091

CG22
G2/mitotic-specific cyclin-2

1

4

Small-scale

0.481

High

637830

MSB1
Morphogenesis-related protein MSB1

1

0

Small-scale

0.460

High

743218

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

Small-scale

0.460

High

744854

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

Small-scale

0.460

High

751669

SEC3
Exocyst complex component SEC3

1

0

Small-scale

0.460

High

811264

RGA1
Rho-type GTPase-activating protein 1

1

0

Small-scale

0.460

High

812223

YM11
Uncharacterized protein YMR124W

1

0

Small-scale

0.460

High

817203

PEA2
Protein PEA2

1

0

Small-scale

0.460

High

817232

MSB4
GTPase-activating protein MSB4

1

0

Small-scale

0.460

High

677142

LRE1
Laminarase-resistance protein LRE1

1

0

High-throughput

0.458

High

796079

IMB2
Importin subunit beta-2

1

0

High-throughput

0.458

High

817207

BNI1
Protein BNI1

1

0

High-throughput

0.458

High

817213

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

575594

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

2

Small-scale

0.439

High

656318

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

2

Small-scale

0.439

High

667058

CG21
G2/mitotic-specific cyclin-1

1

4

Small-scale

0.439

High

667134

CG23
G2/mitotic-specific cyclin-3

1

4

Small-scale

0.439

High

667160

CG24
G2/mitotic-specific cyclin-4

1

4

Small-scale

0.439

High

817234

ENT1
Epsin-1

1

0

Small-scale

0.438

High

718942

CGS5
S-phase entry cyclin-5

1

4

High-throughput

0.417

High

817231

SMT3
Ubiquitin-like protein SMT3

4

0

Small-scale

0.360

High

738750

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

2

0

Small-scale

0.304

High

817222

SPC24
Kinetochore protein SPC24

2

0

Small-scale

0.304

High

817219

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

817226

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

0

Small-scale

0.288

High

660795

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

0

High-throughput

0.269

Low

817230

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.269

Low

548275

FUS1
Nuclear fusion protein FUS1

1

0

High-throughput

0.265

Low

602125

SPO12
Sporulation-specific protein 12

1

0

Small-scale

0.265

Low

816647

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.265

Low

817208

REF2
RNA end formation protein 2

1

0

Small-scale

0.265

Low

817210

BBC1
Myosin tail region-interacting protein MTI1

1

0

High-throughput

0.265

Low

817224

YL456
Pyridoxamine 5'-phosphate oxidase YLR456W homolog

1

0

High-throughput

0.265

Low

449416

SPT2
Protein SPT2

1

0

Small-scale

0.261

Low

557718

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.251

Low

671327

CANB
Calcineurin subunit B

1

0

Small-scale

0.251

Low

700106

PRP45
Pre-mRNA-processing protein 45

1

0

Small-scale

0.251

Low

743339

FIMB
Fimbrin

1

0

Small-scale

0.251

Low

763227

PP2C1
Protein phosphatase 2C homolog 1

1

0

Small-scale

0.251

Low

798415

RGD1
RHO GTPase-activating protein RGD1

1

0

Small-scale

0.251

Low

815788

GDI1
Rab GDP-dissociation inhibitor

1

0

Small-scale

0.251

Low

817202

YEN1
Holliday junction resolvase YEN1

1

0

Small-scale

0.251

Low

817206

GLC8
Protein GLC8

1

0

Small-scale

0.251

Low

817211

BIR1
Chromosomal passenger complex protein BIR1

1

0

High-throughput

0.251

Low

817212

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.251

Low

817214

CDH1
APC/C activator protein CDH1

1

0

Small-scale

0.251

Low

817215

PBP1
PAB1-binding protein 1

1

0

Small-scale

0.251

Low

817220

GIS1
Transcriptional activator/repressor GIS1

1

0

Small-scale

0.251

Low

817227

ELG1
Telomere length regulation protein ELG1

1

0

Small-scale

0.251

Low

817229

NBP2
NAP1-binding protein 2

1

0

Small-scale

0.251

Low

817235

HUB1
Ubiquitin-like modifier HUB1

1

0

Small-scale

0.251

Low

488957

SWI6
Regulatory protein SWI6

1

0

High-throughput

0.249

Low

654783

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.249

Low

666687

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

Small-scale

0.249

Low

668268

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.249

Low

712989

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

744531

DRI1
Putative RNA-binding protein involved in heterochromatin assembly

1

0

High-throughput

0.249

Low

790504

CCL1
Cyclin CCL1

1

0

High-throughput

0.249

Low

793573

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.249

Low

805819

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

817217

H3
Histone H3

1

0

High-throughput

0.249

Low

817218

CTF4
DNA polymerase alpha-binding protein

1

0

High-throughput

0.249

Low

817225

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.249

Low

817228

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.249

Low

817209

FAR3
Factor arrest protein 3

1

0

Small-scale

0.238

Low

817221

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.238

Low

817233

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.238

Low

579462

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

741655

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.232

Low

817204

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low

817205

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025