Protein: APC1
Anaphase-promoting complex subunit 1

Gene: APC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 52
UniProt ID: P53886

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

486788

CDC16
Anaphase-promoting complex subunit CDC16

18

10

Small-scale

0.764

High

924384

APC2
Anaphase-promoting complex subunit 2

7

4

Small-scale

0.752

High

792481

CDC27
Anaphase-promoting complex subunit CDC27

7

9

Small-scale

0.746

High

916908

APC10
Anaphase-promoting complex subunit DOC1

7

3

Small-scale

0.745

High

597617

CDC23
Anaphase-promoting complex subunit CDC23

5

11

Small-scale

0.712

High

924374

APC4
Anaphase-promoting complex subunit 4

6

0

Small-scale

0.701

High

924383

SWM1
Anaphase-promoting complex subunit SWM1

6

0

Small-scale

0.695

High

924380

APC5
Anaphase-promoting complex subunit 5

4

0

Small-scale

0.667

High

827028

MND2
Anaphase-promoting complex subunit MND2

4

0

Small-scale

0.664

High

924382

APC11
Anaphase-promoting complex subunit 11

3

2

Small-scale

0.662

High

575047

CDC26
Anaphase-promoting complex subunit CDC26

4

0

Small-scale

0.654

High

918114

CDH1
APC/C activator protein CDH1

2

10

Small-scale

0.595

High

364677

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.577

High

924371

APC1
Anaphase-promoting complex subunit 1

2

0

Small-scale

0.576

High

826720

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

924381

APC9
Anaphase-promoting complex subunit 9

2

0

Small-scale

0.547

High

739995

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

2

Small-scale

0.536

High

656571

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.513

High

660807

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

2

Small-scale

0.501

High

660872

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

2

Small-scale

0.501

High

924375

SML1
Ribonucleotide reductase inhibitor protein SML1

1

0

High-throughput

0.493

High

864882

MAD3
Spindle assembly checkpoint component MAD3

1

2

High-throughput

0.481

High

524772

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.479

High

602134

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.460

High

664456

MCM3
DNA replication licensing factor MCM3

1

0

High-throughput

0.460

High

745529

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.460

High

796262

QOR
Probable quinone oxidoreductase

1

0

High-throughput

0.460

High

808654

AURK
Aurora kinase

1

0

High-throughput

0.460

High

893386

RPA14
DNA-directed RNA polymerase I subunit RPA14

1

0

High-throughput

0.460

High

924376

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.460

High

924379

SYC1
Protein SYC1

1

0

High-throughput

0.460

High

924385

SFG1
Superficial pseudohyphal growth protein 1

1

0

High-throughput

0.460

High

924386

DDP1
Diphosphoinositol polyphosphate phosphohydrolase DDP1

1

0

High-throughput

0.460

High

603092

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

661549

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.458

High

707833

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

752582

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

797771

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

864795

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

924372

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

924377

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

527362

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

545816

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742124

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

819436

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

653885

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

804357

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

924373

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

924378

BSP1
F-actin capping regulator BSP1

1

0

High-throughput

0.269

Low

744567

UGX2
Protein UGX2

1

0

High-throughput

0.251

Low

919287

FHN1
Non-classical export protein 2 homolog 1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025