Protein: PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase (EC 1.5.5.2) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)]

Gene: PUTA
Organism: Escherichia coli K-12
Interactions: 53
UniProt ID: P09546

Gene Ontology (top 5):
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0003677 - DNA binding
GO:0003842 - L-glutamate gamma-semialdehyde dehydrogenase activity
GO:0004657 - proline dehydrogenase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

483684

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

3

14

Small-scale

0.866

High

483702

CSPC
Cold shock-like protein CspC

2

1

High-throughput

0.588

High

483725

RMLB1
dTDP-glucose 4,6-dehydratase 1

1

1

High-throughput

0.541

High

483685

CH60
Chaperonin GroEL

1

5

High-throughput

0.536

High

483688

DNAK
Chaperone protein DnaK

1

5

High-throughput

0.536

High

483720

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.536

High

483730

CLPB
Chaperone protein ClpB

1

5

High-throughput

0.536

High

483697

TIG
Trigger factor

1

0

High-throughput

0.513

High

483701

PTA
Phosphate acetyltransferase

1

0

High-throughput

0.513

High

483719

YCAC
Probable hydrolase YcaC

1

0

High-throughput

0.513

High

483721

WAAC
Lipopolysaccharide heptosyltransferase 1

1

0

High-throughput

0.513

High

483726

USPG
Universal stress protein UP12

1

0

High-throughput

0.513

High

483728

RATB
UPF0125 protein RatB

1

0

High-throughput

0.513

High

483708

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.479

High

483686

CH10
Co-chaperonin GroES

1

1

High-throughput

0.479

High

483687

ENO
Enolase

1

1

High-throughput

0.479

High

483710

AHPC
Alkyl hydroperoxide reductase C

1

1

High-throughput

0.479

High

483716

EFTU1
Elongation factor Tu 1

1

5

High-throughput

0.479

High

483723

LEUD
3-isopropylmalate dehydratase small subunit

1

3

High-throughput

0.479

High

483733

KAD
Adenylate kinase

1

3

High-throughput

0.479

High

483731

YHES
Probable ATP-binding protein YheS

1

2

High-throughput

0.470

High

483689

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

483690

HSLV
ATP-dependent protease subunit HslV

1

0

High-throughput

0.458

High

483691

RL1
Large ribosomal subunit protein uL1

1

0

High-throughput

0.458

High

483692

RL28
Large ribosomal subunit protein bL28

1

0

High-throughput

0.458

High

483694

RL33
Large ribosomal subunit protein bL33

1

0

High-throughput

0.458

High

483695

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.458

High

483698

TALB
Transaldolase B

1

0

High-throughput

0.458

High

483700

DPO3B
Beta sliding clamp

1

0

High-throughput

0.458

High

483704

ALF
Fructose-bisphosphate aldolase class 2

1

0

High-throughput

0.458

High

483706

DBHA
DNA-binding protein HU-alpha

1

0

High-throughput

0.458

High

483707

HNS
DNA-binding protein H-NS

1

0

High-throughput

0.458

High

483711

ELAB
Protein ElaB

1

0

High-throughput

0.458

High

483712

RISA
Riboflavin synthase

1

0

High-throughput

0.458

High

483713

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.458

High

483715

RL18
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

483732

GRCA
Autonomous glycyl radical cofactor

1

0

High-throughput

0.458

High

483703

THIO
Thioredoxin 1

1

5

Small-scale

0.445

High

483699

CLPS
ATP-dependent Clp protease adapter protein ClpS

1

1

Small-scale

0.407

High

483705

EUTM
Bacterial microcompartment shell protein EutM

1

0

High-throughput

0.279

Low

483717

FECA
Fe(3+) dicitrate transport protein FecA

1

0

High-throughput

0.279

Low

483718

TREA
Periplasmic trehalase

1

0

High-throughput

0.279

Low

483722

WECG
UDP-N-acetyl-D-mannosaminuronic acid transferase

1

0

High-throughput

0.279

Low

483724

RCBA
Double-strand break reduction protein

1

0

High-throughput

0.279

Low

483727

YHAK
Pirin-like protein YhaK

1

0

High-throughput

0.279

Low

483729

MUKF
Chromosome partition protein MukF

1

0

High-throughput

0.279

Low

365889

PPB
Alkaline phosphatase

1

0

High-throughput

0.249

Low

483693

RL29
Large ribosomal subunit protein uL29

1

0

High-throughput

0.249

Low

483696

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.249

Low

483709

RL16
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

483714

RS1
Small ribosomal subunit protein bS1

1

0

High-throughput

0.249

Low

483734

A2MGH
Putative alpha-2-macroglobulin homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025