Protein: SYA
Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Protein lactyltransferase) (EC 6.-.-.-)

Gene: SYA, alaS
Organism: Escherichia coli K-12
Interactions: 24
UniProt ID: P00957

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0002161 - aminoacyl-tRNA deacylase activity
GO:0002196 - Ser-tRNA(Ala) deacylase activity
GO:0004813 - alanine-tRNA ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

368815

SYA
Alanine--tRNA ligase

2

9

Small-scale

0.754

High

368831

RLUB
Ribosomal large subunit pseudouridine synthase B

2

1

High-throughput

0.611

High

368824

GLMS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.537

High

368818

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

368820

RS2
Small ribosomal subunit protein uS2

1

2

High-throughput

0.536

High

368835

CLPB
Chaperone protein ClpB

1

2

High-throughput

0.536

High

368821

MPRA
Transcriptional repressor MprA

1

0

High-throughput

0.513

High

368825

YFAA
Uncharacterized protein YfaA

1

0

High-throughput

0.513

High

368827

ACRD
Probable aminoglycoside efflux pump

1

0

High-throughput

0.513

High

368828

LPXM
Lipid A biosynthesis myristoyltransferase

1

0

High-throughput

0.513

High

368829

GLND
Bifunctional uridylyltransferase/uridylyl-removing enzyme

1

0

High-throughput

0.513

High

368834

ABPB
Anti-bacteriophage protein B

1

0

High-throughput

0.513

High

368822

EFTU1
Elongation factor Tu 1

1

3

High-throughput

0.489

High

368833

YFAL
Probable autotransporter YfaL [Cleaved into: Probable secreted autotransporter protein YfaL; Probable autotransporter YfaL translocator]

1

1

High-throughput

0.489

High

368819

DNAK
Chaperone protein DnaK

1

5

High-throughput

0.484

High

368817

SYE
Glutamate--tRNA ligase

1

2

High-throughput

0.479

High

368823

EFTU2
Elongation factor Tu 2

1

3

High-throughput

0.457

High

368816

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.279

Low

368830

BCSB
Cyclic di-GMP-binding protein

1

0

High-throughput

0.279

Low

368832

RSPA
Starvation-sensing protein RspA

1

0

High-throughput

0.279

Low

368836

YDFR
Uncharacterized protein YdfR

1

0

High-throughput

0.279

Low

368826

ARPA
Ankyrin repeat protein A

1

0

High-throughput

0.261

Low

368837

A2MGH
Putative alpha-2-macroglobulin homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025