Protein: MSL2
E3 ubiquitin-protein ligase MSL2 (EC 2.3.2.27) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184)

Gene: MSL2
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q9HCI7

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006513 - protein monoubiquitination
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1228914

MSL1
Male-specific lethal 1 homolog

5

1

Small-scale

0.922

High

1435955

KAT8
Histone acetyltransferase KAT8

5

1

Small-scale

0.722

High

1328609

MS3L1
MSL complex subunit 3

4

1

Small-scale

0.706

High

1163220

H2B2E
Histone H2B type 2-E

3

0

Small-scale

0.636

High

414663

P53
Cellular tumor antigen p53

2

0

Small-scale

0.603

High

957207

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

0

Small-scale

0.577

High

999411

HBB
Hemoglobin subunit beta

2

1

High-throughput

0.574

High

999686

HBA
Hemoglobin subunit alpha

2

1

High-throughput

0.574

High

396989

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

980364

H4
Histone H4

2

0

Small-scale

0.569

High

1439096

ABC3B
DNA dC->dU-editing enzyme APOBEC-3B

1

0

Small-scale

0.554

High

966899

1433G
14-3-3 protein gamma

1

2

High-throughput

0.541

High

972022

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.518

High

1420185

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

0

High-throughput

0.518

High

675692

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.513

High

1162897

H2A2C
Histone H2A type 2-C

1

1

Small-scale

0.501

High

1232732

H2A2A
Histone H2A type 2-A

1

1

Small-scale

0.501

High

990762

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.481

High

1258955

H32
Histone H3.2

1

0

Small-scale

0.480

High

1330570

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

Small-scale

0.480

High

1367330

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

822873

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

1141950

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

1338979

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

1401399

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1403585

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1405563

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1439095

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1439097

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.458

High

1433312

WNK1
Serine/threonine-protein kinase WNK1

1

0

High-throughput

0.438

High

1333340

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.269

Low

379399

IGHG2
Immunoglobulin heavy constant gamma 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025