Protein: MSL1
Male-specific lethal 1 homolog (MSL-1) (Male-specific lethal 1-like 1) (MSL1-like 1) (Male-specific lethal-1 homolog 1)

Gene: MSL1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q68DK7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
GO:0016607 - nuclear speck
GO:0030674 - protein-macromolecule adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1228913

KAT8
Histone acetyltransferase KAT8

8

3

Small-scale

0.973

High

1228914

MSL2
E3 ubiquitin-protein ligase MSL2

5

1

Small-scale

0.922

High

1228903

MS3L1
MSL complex subunit 3

8

3

Small-scale

0.750

High

1228910

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

5

0

High-throughput

0.686

High

247959

NUPR1
Nuclear protein 1

3

0

Small-scale

0.641

High

1088873

TP53B
TP53-binding protein 1

2

1

Small-scale

0.620

High

1162983

H2B2E
Histone H2B type 2-E

2

1

Small-scale

0.619

High

1228907

KAT6A
Histone acetyltransferase KAT6A

1

4

High-throughput

0.618

High

284325

GEMI
Geminin

2

0

High-throughput

0.602

High

965016

WDR5
WD repeat-containing protein 5

2

0

Small-scale

0.585

High

980841

H2B1C
Histone H2B type 1-C/E/F/G/I

2

1

High-throughput

0.584

High

998430

H31
Histone H3.1

2

1

High-throughput

0.584

High

396309

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

505787

MS3L2
MSL complex subunit 3B

2

1

High-throughput

0.552

High

415639

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

487422

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.513

High

502018

H2AZ
Histone H2A.Z

1

0

High-throughput

0.513

High

601724

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

872427

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

1097347

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.513

High

1228899

F10C1
Protein FRA10AC1

1

0

High-throughput

0.513

High

1228912

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

272684

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

1

Small-scale

0.501

High

1217862

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

1

Small-scale

0.501

High

855885

CRKL
Crk-like protein

1

0

High-throughput

0.486

High

1228917

MO4L1
Mortality factor 4-like protein 1

1

3

Small-scale

0.481

High

957100

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

0

Small-scale

0.480

High

1228904

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

Small-scale

0.480

High

474053

NFIC
Nuclear factor 1 C-type

1

2

High-throughput

0.479

High

521744

H14
Histone H1.4

1

3

High-throughput

0.479

High

595471

H15
Histone H1.5

1

3

High-throughput

0.479

High

595798

H13
Histone H1.3

1

3

High-throughput

0.479

High

596157

H12
Histone H1.2

1

3

High-throughput

0.479

High

1016941

H33
Histone H3.3

1

1

High-throughput

0.479

High

1087797

NFIA
Nuclear factor 1 A-type

1

2

High-throughput

0.479

High

1133463

NFIX
Nuclear factor 1 X-type

1

2

High-throughput

0.479

High

1228905

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

1228906

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1228916

IBTK
Inhibitor of Bruton tyrosine kinase

1

1

High-throughput

0.479

High

187101

PPM1G
Protein phosphatase 1G

1

0

Small-scale

0.460

High

981539

RAN
GTP-binding nuclear protein Ran

1

0

Small-scale

0.460

High

1111042

SNW1
SNW domain-containing protein 1

1

0

Small-scale

0.460

High

1134232

IMB1
Importin subunit beta-1

1

0

Small-scale

0.460

High

1228900

HORM1
HORMA domain-containing protein 1

1

0

Small-scale

0.460

High

1228908

SMRC1
SWI/SNF complex subunit SMARCC1

1

0

Small-scale

0.460

High

1228915

MRGBP
MRG/MORF4L-binding protein

1

0

Small-scale

0.460

High

194234

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

400990

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

675542

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

979821

H4
Histone H4

1

0

High-throughput

0.458

High

1045398

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1129622

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.458

High

1228901

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1228911

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1228918

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1228920

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.458

High

1228921

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

133520

ACATN
Acetyl-coenzyme A transporter 1

1

1

High-throughput

0.437

High

1228902

CNTRB
Centrobin

1

1

High-throughput

0.437

High

1228909

SAHH3
Adenosylhomocysteinase 3

3

0

High-throughput

0.347

High

999367

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.279

Low

1228919

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

318020

TOM70
Mitochondrial import receptor subunit TOM70

1

0

High-throughput

0.269

Low

319221

FCSD2
F-BAR and double SH3 domains protein 2

1

0

High-throughput

0.265

Low

373993

RASN
GTPase NRas

1

0

High-throughput

0.249

Low

1226131

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025