Protein: ATG8
Autophagy-related protein 8 (Autophagy-related ubiquitin-like modifier ATG8) (Cytoplasm to vacuole targeting protein 5)

Gene: ATG8
Organism: Saccharomyces cerevisiae S288C
Interactions: 143
UniProt ID: P38182

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000329 - fungal-type vacuole membrane
GO:0000407 - phagophore assembly site
GO:0000421 - autophagosome membrane
GO:0000422 - autophagy of mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

745982

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

15

20

Small-scale

0.990

High

746022

ATG4
Cysteine protease ATG4

8

20

Small-scale

0.975

High

745998

ATG3
Autophagy-related protein 3

21

12

Small-scale

0.767

High

715886

ATG19
Autophagy-related protein 19

11

1

Small-scale

0.760

High

746018

ATG1
Serine/threonine-protein kinase ATG1

6

13

Small-scale

0.741

High

746001

ATG32
Autophagy-related protein 32

8

0

Small-scale

0.719

High

746050

ATG34
Autophagy-related protein 34

5

1

Small-scale

0.715

High

541544

AMPL
Vacuolar aminopeptidase 1

4

2

Small-scale

0.680

High

746057

ATG40
Autophagy-related protein 40

4

0

Small-scale

0.674

High

746043

CUE5
Ubiquitin-binding protein CUE5

2

0

Small-scale

0.626

High

611771

BET1
Protein transport protein BET1

2

1

Small-scale

0.621

High

746002

NU159
Nucleoporin NUP159

3

12

Small-scale

0.620

High

746031

ATG21
Autophagy-related protein 21

2

2

Small-scale

0.609

High

746038

ATG39
Autophagy-related protein 39

2

0

Small-scale

0.605

High

614623

KC11
Casein kinase I homolog 1

2

2

High-throughput

0.595

High

636600

CDC48
Cell division control protein 48

2

4

Small-scale

0.595

High

745974

ATG12
Ubiquitin-like protein ATG12

2

3

Small-scale

0.595

High

710373

EDE1
EH domain-containing and endocytosis protein 1

1

3

Small-scale

0.586

High

421623

FAS1
Fatty acid synthase subunit beta

2

7

Small-scale

0.584

High

580543

FAS2
Fatty acid synthase subunit alpha

2

5

Small-scale

0.584

High

745987

TCPB
T-complex protein 1 subunit beta

1

20

Small-scale

0.561

High

691685

NDC1
Nucleoporin NDC1

2

0

Small-scale

0.559

High

696567

SEC17
Alpha-soluble NSF attachment protein

2

0

Small-scale

0.559

High

734005

NU133
Nucleoporin NUP133

2

0

Small-scale

0.559

High

745999

NUP82
Nucleoporin NUP82

2

0

Small-scale

0.559

High

746048

NYV1
Vacuolar v-SNARE NYV1

1

1

Small-scale

0.554

High

710542

UBX1
UBX domain-containing protein 1

1

0

Small-scale

0.549

High

733553

HFL1
Vacuole membrane protein HFL1

2

1

Small-scale

0.543

High

745972

CCZ1
Vacuolar fusion protein CCZ1

1

0

Small-scale

0.537

High

541875

NSP1
Nucleoporin NSP1

2

8

Small-scale

0.533

High

745620

NU170
Nucleoporin NUP170

2

2

Small-scale

0.533

High

745995

NU157
Nucleoporin NUP157

2

2

Small-scale

0.533

High

746013

NUP57
Nucleoporin NUP57

2

12

Small-scale

0.533

High

746015

NU145
Nucleoporin NUP145

2

14

Small-scale

0.533

High

746028

NUP49
Nucleoporin NUP49/NSP49

2

11

Small-scale

0.533

High

746030

NU116
Nucleoporin NUP116/NSP116

2

13

Small-scale

0.533

High

746047

VAM3
Syntaxin VAM3

1

2

Small-scale

0.515

High

746044

GYP1
GTPase-activating protein GYP1

1

20

Small-scale

0.512

High

565556

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

745978

KSP1
Serine/threonine-protein kinase KSP1

1

13

High-throughput

0.501

High

746052

ATG5
Autophagy protein 5

1

9

Small-scale

0.501

High

746049

CRC1
Mitochondrial carnitine carrier

1

10

High-throughput

0.494

High

746032

STE20
Serine/threonine-protein kinase STE20

1

12

Small-scale

0.481

High

648150

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

746041

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

0

Small-scale

0.480

High

350872

YPT1
GTP-binding protein YPT1

1

5

High-throughput

0.479

High

419686

RHO1
GTP-binding protein RHO1

1

4

High-throughput

0.479

High

429199

SEC4
Ras-related protein SEC4

1

7

High-throughput

0.479

High

746035

ERP1
Protein ERP1

1

3

High-throughput

0.479

High

546724

SEC23
Protein transport protein SEC23

1

17

High-throughput

0.479

High

594397

SAR1
Small COPII coat GTPase SAR1

1

8

High-throughput

0.479

High

599457

VPS1
Vacuolar protein sorting-associated protein 1

1

1

High-throughput

0.479

High

604395

CLH
Clathrin heavy chain

1

11

Small-scale

0.479

High

635287

SYP1
Suppressor of yeast profilin deletion

1

8

Small-scale

0.479

High

685511

COPG
Coatomer subunit gamma

1

6

High-throughput

0.479

High

690306

CDC11
Cell division control protein 11

1

6

Small-scale

0.479

High

691624

NUP2
Nucleoporin NUP2

1

4

Small-scale

0.479

High

692221

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

9

Small-scale

0.479

High

696447

FIMB
Fimbrin

1

9

High-throughput

0.479

High

697915

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

5

Small-scale

0.479

High

698400

EMP24
Endosomal protein P24B

1

2

High-throughput

0.479

High

699193

PEP12
Syntaxin PEP12

1

1

High-throughput

0.479

High

701767

YPT7
Ypt/Rab-type GTPase YPT7

1

11

High-throughput

0.479

High

731170

VPS21
Vacuolar protein sorting-associated protein 21

1

7

High-throughput

0.479

High

745976

YPT31
GTP-binding protein YPT31/YPT8

1

5

High-throughput

0.479

High

745979

GOSR1
Golgi SNAP receptor complex member 1

1

1

High-throughput

0.479

High

745980

DNPEP
Aspartyl aminopeptidase 4

1

2

Small-scale

0.479

High

745986

END3
Actin cytoskeleton-regulatory complex protein END3

1

4

Small-scale

0.479

High

745990

ERV46
ER-derived vesicles protein ERV46

1

1

High-throughput

0.479

High

745991

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.479

High

745993

RSP5
E3 ubiquitin-protein ligase RSP5

1

9

Small-scale

0.479

High

745994

KC13
Casein kinase I homolog 3

1

3

High-throughput

0.479

High

745996

GLE2
mRNA export factor GLE2

1

6

Small-scale

0.479

High

746005

COPB
Coatomer subunit beta

1

3

High-throughput

0.479

High

746020

AP18B
Clathrin coat assembly protein AP180B

1

3

Small-scale

0.479

High

746025

TMEDA
Endoplasmic reticulum vesicle protein 25

1

3

High-throughput

0.479

High

746027

SED5
Integral membrane protein SED5

1

2

High-throughput

0.479

High

746039

SHS1
Seventh homolog of septin 1

1

5

Small-scale

0.479

High

746040

VPS13
Intermembrane lipid transfer protein VPS13

1

7

High-throughput

0.479

High

746042

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

1

High-throughput

0.479

High

746045

AKR2
Probable palmitoyltransferase AKR2

1

12

High-throughput

0.479

High

746046

ATG9
Autophagy-related protein 9

1

1

Small-scale

0.479

High

746055

ENT1
Epsin-1

1

7

Small-scale

0.479

High

605838

SEC22
Protein transport protein SEC22

1

0

High-throughput

0.458

High

612089

MAN1
Alpha-mannosidase

1

0

Small-scale

0.458

High

699485

SSO1
Protein SSO1

1

0

High-throughput

0.458

High

701295

VPS17
Vacuolar protein sorting-associated protein 17

1

0

High-throughput

0.458

High

734097

TVP38
Golgi apparatus membrane protein TVP38

1

0

High-throughput

0.458

High

741287

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.458

High

745449

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.458

High

745973

FTH1
Iron transporter FTH1

1

0

High-throughput

0.458

High

745983

SVP26
Protein SVP26

1

0

High-throughput

0.458

High

745992

SS120
Protein SSP120

1

0

High-throughput

0.458

High

745997

PEP8
Carboxypeptidase Y-deficient protein 8

1

0

High-throughput

0.458

High

746000

VTH1
VPS10 homolog 1

1

0

High-throughput

0.458

High

746004

GVP36
Protein GVP36

1

0

High-throughput

0.458

High

746007

EMP47
Protein EMP47

1

0

High-throughput

0.458

High

746008

SFT1
Protein transport protein SFT1

1

0

High-throughput

0.458

High

746019

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

746021

PRA1
Prenylated Rab acceptor 1

1

0

High-throughput

0.458

High

746026

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.458

High

746034

VTI1
t-SNARE VTI1

1

0

High-throughput

0.458

High

746036

PAL1
Protein PAL1

1

0

Small-scale

0.458

High

746024

MPS1
Serine/threonine-protein kinase MPS1

1

2

High-throughput

0.457

High

450021

HSP73
Heat shock protein SSA3

1

18

High-throughput

0.445

High

493777

HSP72
Heat shock protein SSA2

1

18

High-throughput

0.445

High

511055

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.445

High

416223

SIR2
NAD-dependent histone deacetylase SIR2

1

5

Small-scale

0.437

High

530073

ATC1
Calcium-transporting ATPase 1

1

2

High-throughput

0.437

High

572038

CLC1
Clathrin light chain

1

2

Small-scale

0.437

High

595022

NUP1
Nucleoporin NUP1

1

19

Small-scale

0.437

High

629554

CDC10
Cell division control protein 10

1

5

Small-scale

0.437

High

697472

ATC5
Phospholipid-transporting ATPase DNF1

1

3

High-throughput

0.437

High

710752

CASP
Protein CASP

1

2

High-throughput

0.437

High

745036

AP3M
AP-3 complex subunit mu

1

3

High-throughput

0.437

High

745981

AP18A
Clathrin coat assembly protein AP180A

1

3

Small-scale

0.437

High

745985

AKR1
Palmitoyltransferase AKR1

1

12

High-throughput

0.437

High

745988

ATC3
Phospholipid-transporting ATPase DRS2

1

5

High-throughput

0.437

High

746003

ATC7
Phospholipid-transporting ATPase NEO1

1

4

High-throughput

0.437

High

746014

NUP42
Nucleoporin NUP42

1

11

Small-scale

0.437

High

746029

NU100
Nucleoporin NUP100/NSP100

1

13

Small-scale

0.437

High

746037

ENT2
Epsin-2

1

7

Small-scale

0.437

High

746056

ATC4
Phospholipid-transporting ATPase DNF2

1

3

High-throughput

0.437

High

746011

NU192
Nucleoporin NUP192

2

0

Small-scale

0.323

High

746010

ATG36
Autophagy-related protein 36

2

0

Small-scale

0.313

High

709310

NIC96
Nucleoporin NIC96

2

0

Small-scale

0.305

High

745989

PO152
Nucleoporin POM152

2

0

Small-scale

0.305

High

746016

NU188
Nucleoporin NUP188

2

0

Small-scale

0.305

High

746017

NUP84
Nucleoporin NUP84

2

0

Small-scale

0.305

High

746033

NUP53
Nucleoporin NUP53

2

0

Small-scale

0.305

High

746054

POM34
Nucleoporin POM34

2

0

Small-scale

0.305

High

746051

ATP14
ATP synthase subunit H, mitochondrial

1

0

High-throughput

0.269

Low

520335

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

Small-scale

0.249

Low

630104

ELO2
Fatty acid elongase 2

1

0

High-throughput

0.249

Low

728183

NU120
Nucleoporin NUP120

1

0

Small-scale

0.249

Low

745975

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

745977

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.249

Low

745984

ALP1
Basic amino-acid permease

1

0

Small-scale

0.249

Low

746006

UFE1
Syntaxin UFE1

1

0

Small-scale

0.249

Low

746009

NUP85
Nucleoporin NUP85

1

0

Small-scale

0.249

Low

746012

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.249

Low

746023

SUR7
Protein SUR7

1

0

High-throughput

0.249

Low

746053

YOP1
Protein YOP1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024