Protein: MRH4
ATP-dependent RNA helicase MRH4, mitochondrial (EC 3.6.4.13) (Mitochondrial RNA helicase 4)

Gene: MRH4
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P53166

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005730 - nucleolus
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

725737

RM09
Large ribosomal subunit protein uL3m

3

4

Small-scale

0.643

High

554624

RM02
Large ribosomal subunit protein bL27m

1

1

Small-scale

0.618

High

584249

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

16

Small-scale

0.618

High

682344

SPB4
ATP-dependent rRNA helicase SPB4

1

17

High-throughput

0.618

High

740549

SUV3
ATP-dependent RNA helicase SUV3, mitochondrial

1

6

Small-scale

0.618

High

917885

MRH4
ATP-dependent RNA helicase MRH4, mitochondrial

1

16

High-throughput

0.618

High

917894

DHR1
Probable ATP-dependent RNA helicase DHR1

1

15

High-throughput

0.618

High

524624

HSP71
Heat shock protein SSA1

2

11

High-throughput

0.611

High

917893

POLH
DNA polymerase eta

1

0

High-throughput

0.518

High

394751

EF1A
Elongation factor 1-alpha

1

2

Small-scale

0.479

High

432641

RL7A
Large ribosomal subunit protein uL30A

1

6

High-throughput

0.479

High

510662

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

579772

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

640724

RT28
Small ribosomal subunit protein uS15m

1

1

Small-scale

0.479

High

646470

RAD53
Serine/threonine-protein kinase RAD53

1

3

High-throughput

0.479

High

670192

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

Small-scale

0.479

High

674734

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.479

High

783934

RM07
Large ribosomal subunit protein uL5m

1

3

Small-scale

0.479

High

783999

RM10
Large ribosomal subunit protein uL15m

1

1

High-throughput

0.479

High

784333

RM17
Large ribosomal subunit protein mL46

1

1

Small-scale

0.479

High

792623

RM16
Large ribosomal subunit protein uL16m

1

2

Small-scale

0.479

High

811678

DSS1
Exoribonuclease II, mitochondrial

1

7

Small-scale

0.479

High

866089

RT07
Small ribosomal subunit protein uS7m

1

2

Small-scale

0.479

High

909779

RL4P
Large ribosomal subunit protein uL4m

1

2

High-throughput

0.479

High

917806

MNP1
Large ribosomal subunit protein bL12m

1

1

Small-scale

0.479

High

917886

RM22
Large ribosomal subunit protein uL22m

1

2

Small-scale

0.479

High

917891

MTG1
Mitochondrial GTPase 1

1

7

Small-scale

0.479

High

478419

EI2BG
Translation initiation factor eIF2B subunit gamma

1

1

High-throughput

0.470

High

382956

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

554520

RT13
Small ribosomal subunit protein mS27

1

0

Small-scale

0.458

High

605397

RTPT
Small ribosomal subunit protein mS26

1

0

Small-scale

0.458

High

627079

KGD4
Alpha-ketoglutarate dehydrogenase subunit 4, mitochondrial

1

0

Small-scale

0.458

High

672552

RM32
Large ribosomal subunit protein bL32m

1

0

Small-scale

0.458

High

678195

IMG1
Large ribosomal subunit protein bL19m

1

0

Small-scale

0.458

High

678605

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.458

High

780417

RT22
Ribosome assembly protein RSM22, mitochondrial

1

0

Small-scale

0.458

High

784115

RM15
Large ribosomal subunit protein mL57

1

0

Small-scale

0.458

High

784267

RM28
Large ribosomal subunit protein mL40

1

0

Small-scale

0.458

High

784494

RM40
Large ribosomal subunit protein uL24m

1

0

Small-scale

0.458

High

815698

OXA1
Mitochondrial inner membrane protein OXA1

1

0

Small-scale

0.458

High

917889

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.458

High

917895

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

917896

RM35
Large ribosomal subunit protein mL38

1

0

Small-scale

0.458

High

527235

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

545644

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

577181

SEC63
Protein translocation protein SEC63

1

5

High-throughput

0.445

High

742902

HSP79
Heat shock protein homolog SSE2

1

14

High-throughput

0.445

High

433751

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.437

High

435240

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.437

High

503150

RS22A
Small ribosomal subunit protein uS8A

1

4

High-throughput

0.437

High

513123

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

553549

PDR1
Transcription factor PDR1

1

1

High-throughput

0.437

High

596935

PDC5
Pyruvate decarboxylase isozyme 2

1

1

High-throughput

0.437

High

741018

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

15

High-throughput

0.437

High

753485

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

917888

H3
Histone H3

1

10

High-throughput

0.437

High

917890

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.437

High

917892

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

917897

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

917899

SGO1
Shugoshin

1

3

High-throughput

0.437

High

917900

YRA1
RNA annealing protein YRA1

1

11

High-throughput

0.437

High

917887

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

2

High-throughput

0.417

High

917898

RBX1
RING-box protein HRT1

1

4

High-throughput

0.417

High


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Last updated: 11Aug2025