HitPredict - High confidence protein-protein interactions

Protein: EDN1
Endothelin-1 (Preproendothelin-1) (PPET1) [Cleaved into: Endothelin-1 (ET-1); Big endothelin-1]

Gene: EDN1
Organism: Homo sapiens
Interactions: 9
UniProt ID: P05305

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001516 - prostaglandin biosynthetic process
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001701 - in utero embryonic development
GO:0001821 - histamine secretion

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
399203	EDNRA Endothelin-1 receptor	2	2	Small-scale	0.768	High
399201	EDN1 Endothelin-1	1	0	Small-scale	0.674	High
399202	EDNRB Endothelin receptor type B	1	2	Small-scale	0.618	High
399204	BAG6 Large proline-rich protein BAG6	1	1	High-throughput	0.541	High
399208	UBQL4 Ubiquilin-4	1	1	High-throughput	0.541	High
399206	CSN6 COP9 signalosome complex subunit 6	1	0	High-throughput	0.518	High
399205	H2B2E Histone H2B type 2-E	1	1	High-throughput	0.479	High
399207	H2B1H Histone H2B type 1-H	1	1	High-throughput	0.437	High

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024