Protein: PROA
Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (GSA dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)

Gene: PROA, PRO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P54885

Gene Ontology (top 5):
GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932835

PROA
Gamma-glutamyl phosphate reductase

1

15

High-throughput

0.698

High

678786

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

6

1

High-throughput

0.668

High

682931

MSH2
DNA mismatch repair protein MSH2

2

0

High-throughput

0.595

High

579888

HSC82
ATP-dependent molecular chaperone HSC82

2

7

High-throughput

0.584

High

850144

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

6

High-throughput

0.584

High

393166

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.571

High

527420

HSP72
Heat shock protein SSA2

2

17

High-throughput

0.552

High

545894

SSB1
Ribosome-associated molecular chaperone SSB1

2

16

High-throughput

0.552

High

475175

CISY2
Citrate synthase, peroxisomal

1

3

High-throughput

0.515

High

698117

PEP3
Vacuolar membrane protein PEP3

1

1

High-throughput

0.515

High

836081

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.494

High

651975

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.480

High

671009

SIS1
Protein SIS1

1

8

High-throughput

0.479

High

679957

CDC48
Cell division control protein 48

1

7

High-throughput

0.479

High

707893

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

723630

MLS1
Malate synthase 1

1

2

High-throughput

0.479

High

735106

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

737922

HOG1
Mitogen-activated protein kinase HOG1

1

5

High-throughput

0.479

High

793630

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

1

High-throughput

0.479

High

824692

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

6

High-throughput

0.479

High

932840

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.479

High

914894

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.460

High

481909

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

809468

MPT5
Suppressor protein MPT5

1

0

High-throughput

0.458

High

932836

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

932839

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

822272

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

4

High-throughput

0.457

High

394812

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

524833

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.445

High

676252

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

742170

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

819496

SSB2
Ribosome-associated molecular chaperone SSB2

1

16

High-throughput

0.445

High

932841

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

668351

TSR4
20S rRNA accumulation protein 4

1

0

High-throughput

0.438

High

795146

NU170
Nucleoporin NUP170

1

4

High-throughput

0.437

High

919316

TPO2
Polyamine transporter 2

1

1

High-throughput

0.437

High

932842

DBP10
ATP-dependent RNA helicase DBP10

1

3

High-throughput

0.437

High

932837

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

577193

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.407

High

836625

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

0

High-throughput

0.282

High

932838

AUS1
ATP-dependent permease AUS1

1

0

High-throughput

0.261

Low

793059

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

794833

KMO
Kynurenine 3-monooxygenase

1

0

High-throughput

0.249

Low

877879

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

917523

YGL7
Uncharacterized protein YGL117W

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025