Protein: PURA
Adenylosuccinate synthetase (AMPSase) (AS-synthetase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)

Gene: PURA, ADE12
Organism: Saccharomyces cerevisiae S288C
Interactions: 39
UniProt ID: P80210

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003688 - DNA replication origin binding
GO:0004019 - adenylosuccinate synthase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

579893

HSC82
ATP-dependent molecular chaperone HSC82

3

2

High-throughput

0.640

High

815535

RSP5
E3 ubiquitin-protein ligase RSP5

2

0

Small-scale

0.577

High

727243

HS104
Heat shock protein 104

2

0

High-throughput

0.559

High

524840

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.536

High

704643

SBA1
Co-chaperone protein SBA1

1

1

Small-scale

0.527

High

394061

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.515

High

1009780

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.493

High

849922

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

393169

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

518363

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.479

High

1009785

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

735108

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

803650

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

864803

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

918647

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

1009781

ESP1
Separin

1

0

High-throughput

0.458

High

1009787

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

651976

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

1

High-throughput

0.457

High

545902

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

626849

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.445

High

742174

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

819500

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

577569

CYC8
General transcriptional corepressor CYC8

1

1

Small-scale

0.437

High

671012

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

679961

CDC48
Cell division control protein 48

1

2

High-throughput

0.437

High

823288

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

850646

ERJ5
ER-localized J domain-containing protein 5

1

1

High-throughput

0.407

High

750287

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

822273

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.261

Low

863939

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.261

Low

1009784

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.261

Low

1009786

AUS1
ATP-dependent permease AUS1

1

0

High-throughput

0.261

Low

707899

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

806794

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

850146

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

1009782

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

1009783

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

1009788

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

1009789

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025