Protein: SYRC
Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)

Gene: SYRC, YDR341C
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: Q05506

Gene Ontology (top 5):
GO:0004814 - arginine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006420 - arginyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580067

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

850207

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

819795

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

628095

FKBP
FK506-binding protein 1

1

0

High-throughput

0.513

High

393328

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

399378

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

3

High-throughput

0.479

High

518390

IF4A
ATP-dependent RNA helicase eIF4A

1

2

High-throughput

0.479

High

548726

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.479

High

554734

YPK1
Serine/threonine-protein kinase YPK1

1

1

High-throughput

0.479

High

616452

SEC18
Vesicular-fusion protein SEC18

1

2

High-throughput

0.479

High

632826

DBP5
ATP-dependent RNA helicase DBP5

1

1

High-throughput

0.479

High

639069

VPS1
Vacuolar protein sorting-associated protein 1

1

1

High-throughput

0.479

High

671126

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

680063

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

727310

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

750781

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

796124

IMB2
Importin subunit beta-2

1

1

High-throughput

0.479

High

812118

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

1039039

IMA1
Importin subunit alpha

1

1

High-throughput

0.479

High

1045088

SXM1
Importin beta SMX1

1

1

High-throughput

0.479

High

1051188

CSR1
Phosphatidylinositol transfer protein CSR1

1

1

High-throughput

0.479

High

1051190

SUB2
ATP-dependent RNA helicase SUB2

1

2

High-throughput

0.479

High

1051194

DBP10
ATP-dependent RNA helicase DBP10

1

3

High-throughput

0.479

High

1051195

AHA1
Hsp90 co-chaperone AHA1

1

1

High-throughput

0.479

High

536170

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.458

High

553657

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.458

High

636957

CCA1
CCA tRNA nucleotidyltransferase, mitochondrial

1

0

High-throughput

0.458

High

649673

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.458

High

748046

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

795535

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

805310

GGA2
ADP-ribosylation factor-binding protein GGA2

1

0

High-throughput

0.458

High

806819

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

812656

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

924677

NRK1
Nicotinamide riboside kinase

1

0

High-throughput

0.458

High

1038555

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.458

High

1040552

ESP1
Separin

1

0

High-throughput

0.458

High

1046170

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

1051186

IMB1
Importin subunit beta-1

1

0

High-throughput

0.458

High

546272

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

798071

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

3

High-throughput

0.445

High

368254

TRP
Tryptophan synthase

1

1

High-throughput

0.437

High

671710

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.437

High

803686

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

525151

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

597758

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.426

High

816407

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

850652

ERJ5
ER-localized J domain-containing protein 5

1

1

High-throughput

0.407

High

1051193

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

826528

IST3
U2 snRNP component IST3

1

0

High-throughput

0.279

Low

528640

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.249

Low

708184

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709982

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

722259

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

795217

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

807847

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

919169

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

Small-scale

0.249

Low

919403

RBG2
Ribosome-interacting GTPase 2

1

0

High-throughput

0.249

Low

963719

H3
Histone H3

1

0

High-throughput

0.249

Low

1009782

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.249

Low

1051187

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1051189

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

1051191

YP225
Protein PBDC1 homolog

1

0

High-throughput

0.249

Low

1051192

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025