Protein: REG1
Resistance to glucose repression protein 1 (Protein HEX2) (Second-site suppressor of the rna1-1 mutation 1)

Gene: REG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: Q00816

Gene Ontology (top 5):
GO:0000164 - protein phosphatase type 1 complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005773 - vacuole
GO:0006986 - response to unfolded protein

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743269

PP12
Serine/threonine-protein phosphatase PP1-2

13

1

Small-scale

0.761

High

709929

BMH1
Protein BMH1

9

1

Small-scale

0.754

High

448781

SNF1
Carbon catabolite-derepressing protein kinase

13

0

Small-scale

0.729

High

760327

BMH2
Protein BMH2

5

1

Small-scale

0.715

High

557026

AAKG
5'-AMP-activated protein kinase subunit gamma

3

0

High-throughput

0.634

High

545922

SSB1
Ribosome-associated molecular chaperone SSB1

3

1

Small-scale

0.633

High

524863

HSP71
Heat shock protein SSA1

3

0

High-throughput

0.606

High

679973

CDC48
Cell division control protein 48

2

0

High-throughput

0.602

High

1026963

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

2

0

High-throughput

0.595

High

722173

XPO1
Exportin-1

2

0

Small-scale

0.592

High

1027370

GCN5
Histone acetyltransferase GCN5

2

0

Small-scale

0.592

High

1027371

GAL83
SNF1 protein kinase subunit beta-3

2

0

High-throughput

0.576

High

819520

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

Small-scale

0.571

High

894390

SOL1
6-phosphogluconolactonase-like protein 1

2

0

High-throughput

0.563

High

393183

HSP82
ATP-dependent molecular chaperone HSP82

2

0

High-throughput

0.559

High

470755

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

2

0

Small-scale

0.559

High

808624

SAK1
SNF1-activating kinase 1

2

0

Small-scale

0.559

High

416561

HXKB
Hexokinase-2

2

0

Small-scale

0.551

High

1027377

HRK1
Serine/threonine-protein kinase HRK1

1

1

High-throughput

0.536

High

666702

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

Small-scale

0.529

High

676666

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.513

High

780160

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

0

High-throughput

0.513

High

793971

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.513

High

893324

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.513

High

917851

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.513

High

1027381

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.513

High

815838

BEM2
GTPase-activating protein BEM2/IPL2

1

0

High-throughput

0.493

High

925490

IDHH
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.493

High

1009780

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.493

High

602605

PHO85
Cyclin-dependent protein kinase PHO85

1

0

Small-scale

0.480

High

667043

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.480

High

381212

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381599

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

646151

NPR1
Nitrogen permease reactivator protein

1

2

High-throughput

0.479

High

430904

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

Small-scale

0.460

High

1027368

ROD1
Protein ROD1

1

0

Small-scale

0.460

High

382281

H4
Histone H4

1

0

High-throughput

0.458

High

449425

SPT2
Protein SPT2

1

0

Small-scale

0.458

High

479696

F16P
Fructose-1,6-bisphosphatase

1

0

Small-scale

0.458

High

707916

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

740528

SIP1
SNF1 protein kinase subunit beta-1

1

0

High-throughput

0.458

High

763361

TAF14
Transcription initiation factor TFIID subunit 14

1

0

Small-scale

0.458

High

826052

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

850152

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

963649

H3
Histone H3

1

0

High-throughput

0.458

High

1027369

IMA1
Importin subunit alpha

1

0

Small-scale

0.458

High

1027373

IMB1
Importin subunit beta-1

1

0

Small-scale

0.458

High

1027374

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

1027376

PUF3
mRNA-binding protein PUF3

1

0

High-throughput

0.458

High

1027380

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

742188

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

804379

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

807255

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

811371

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

824519

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

898184

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

1027367

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.426

High

1027372

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.426

High

1027379

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.426

High

926261

PUR91
Bifunctional purine biosynthesis protein ADE16 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

2

0

High-throughput

0.320

High

803912

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.269

Low

811135

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.249

Low

864310

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

1027378

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

1027375

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025