Protein: RLMN
Dual-specificity RNA methyltransferase RlmN (EC 2.1.1.192) (23S rRNA (adenine(2503)-C(2))-methyltransferase) (23S rRNA m2A2503 methyltransferase) (Ribosomal RNA large subunit methyltransferase N) (tRNA (adenine(37)-C(2))-methyltransferase) (tRNA m2A37 methyltransferase)

Gene: RLMN
Organism: Escherichia coli K-12
Interactions: 101
UniProt ID: P36979

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002935 - tRNA (adenine(37)-C2)-methyltransferase activity
GO:0005829 - cytosol
GO:0019843 - rRNA binding
GO:0030488 - tRNA methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

788369

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.663

High

494157

RS4
Small ribosomal subunit protein uS4

3

0

High-throughput

0.629

High

469953

PHOR
Phosphate regulon sensor protein PhoR

3

0

High-throughput

0.628

High

638609

SRMB
ATP-dependent RNA helicase SrmB

2

1

High-throughput

0.620

High

384047

RL15
Large ribosomal subunit protein uL15

2

0

High-throughput

0.613

High

421125

PNP
Polyribonucleotide nucleotidyltransferase

2

1

High-throughput

0.611

High

506286

EFTU1
Elongation factor Tu 1

2

2

High-throughput

0.611

High

569570

SELB
Selenocysteine-specific elongation factor

2

3

High-throughput

0.611

High

788374

RL3
Large ribosomal subunit protein uL3

2

0

High-throughput

0.602

High

491452

IF2
Translation initiation factor IF-2

2

5

High-throughput

0.588

High

495632

SYK1
Lysine--tRNA ligase

2

1

High-throughput

0.588

High

498396

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

1

High-throughput

0.588

High

500248

ELAB
Protein ElaB

2

1

High-throughput

0.588

High

788379

CLPB
Chaperone protein ClpB

2

1

High-throughput

0.588

High

492772

RL1
Large ribosomal subunit protein uL1

2

0

High-throughput

0.585

High

788373

RL2
Large ribosomal subunit protein uL2

2

0

High-throughput

0.585

High

382591

RS6
Small ribosomal subunit protein bS6

2

0

High-throughput

0.585

High

501187

RL17
Large ribosomal subunit protein bL17

2

0

High-throughput

0.585

High

788382

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

2

0

High-throughput

0.585

High

490421

DAPF
Diaminopimelate epimerase

2

0

High-throughput

0.563

High

490528

EFG
Elongation factor G

2

0

High-throughput

0.563

High

491508

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

2

0

High-throughput

0.563

High

492539

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.563

High

492875

RL27
Large ribosomal subunit protein bL27

2

0

High-throughput

0.563

High

492976

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.563

High

493047

RL29
Large ribosomal subunit protein uL29

2

0

High-throughput

0.563

High

493545

RS18
Small ribosomal subunit protein bS18

2

0

High-throughput

0.563

High

495050

TPIS
Triosephosphate isomerase

2

0

High-throughput

0.563

High

497111

DEAD
ATP-dependent RNA helicase DeaD

2

0

High-throughput

0.563

High

499041

HINT
Purine nucleoside phosphoramidase

2

0

High-throughput

0.563

High

499737

YIBL
Uncharacterized protein YibL

2

0

High-throughput

0.563

High

499780

YGAM
Uncharacterized protein YgaM

2

0

High-throughput

0.563

High

500454

GYRB
DNA gyrase subunit B

2

0

High-throughput

0.563

High

500488

SKP
Chaperone protein Skp

2

0

High-throughput

0.563

High

501103

SPOT
Bifunctional

2

0

High-throughput

0.563

High

501337

RS14
Small ribosomal subunit protein uS14

2

0

High-throughput

0.563

High

501647

YHBY
RNA-binding protein YhbY

2

0

High-throughput

0.563

High

450041

OMPC
Outer membrane porin C

1

1

High-throughput

0.561

High

473316

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.537

High

638578

RNR
Ribonuclease R

1

0

High-throughput

0.537

High

788370

RLMJ
Ribosomal RNA large subunit methyltransferase J

1

0

High-throughput

0.537

High

788371

RLUB
Ribosomal large subunit pseudouridine synthase B

1

0

High-throughput

0.537

High

382733

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

489808

CH60
Chaperonin GroEL

1

0

High-throughput

0.513

High

494322

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

497034

DLDH
Dihydrolipoyl dehydrogenase

1

0

High-throughput

0.513

High

500807

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.513

High

616917

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

638625

RNE
Ribonuclease E

1

0

High-throughput

0.513

High

722843

3PASE
Inorganic triphosphatase

1

0

High-throughput

0.513

High

506344

EFTU2
Elongation factor Tu 2

1

2

High-throughput

0.500

High

393995

PHOE
Outer membrane porin PhoE

1

1

High-throughput

0.489

High

495666

SYK2
Lysine--tRNA ligase, heat inducible

1

1

High-throughput

0.484

High

788378

RL5
Large ribosomal subunit protein uL5

1

1

High-throughput

0.484

High

492635

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

492844

RL20
Large ribosomal subunit protein bL20

1

0

High-throughput

0.464

High

493175

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

493268

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.464

High

493956

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.464

High

494749

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.464

High

495583

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.464

High

495848

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.464

High

496916

LON
Lon protease

1

0

High-throughput

0.464

High

497521

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

499078

DBHA
DNA-binding protein HU-alpha

1

0

High-throughput

0.464

High

499939

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.464

High

501246

RL21
Large ribosomal subunit protein bL21

1

0

High-throughput

0.464

High

501289

RL6
Large ribosomal subunit protein uL6

1

0

High-throughput

0.464

High

501609

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

501676

RL18
Large ribosomal subunit protein uL18

1

0

High-throughput

0.464

High

505910

GATY
D-tagatose-1,6-bisphosphate aldolase subunit GatY

1

0

High-throughput

0.464

High

515973

RCSB
Transcriptional regulatory protein RcsB

1

0

High-throughput

0.464

High

788375

RL24
Large ribosomal subunit protein uL24

1

0

High-throughput

0.464

High

788376

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

788377

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

493421

RS13
Small ribosomal subunit protein uS13

1

0

High-throughput

0.458

High

493646

RS20
Small ribosomal subunit protein bS20

1

0

High-throughput

0.458

High

788380

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

1

0

High-throughput

0.458

High

501392

RS1
Small ribosomal subunit protein bS1

1

1

High-throughput

0.442

High

450023

MALT
HTH-type transcriptional regulator MalT

2

0

High-throughput

0.330

High

393931

MELB
Melibiose permease

2

0

High-throughput

0.318

High

393998

MCP1
Methyl-accepting chemotaxis protein I

2

0

High-throughput

0.318

High

521489

SECA
Protein translocase subunit SecA

2

0

High-throughput

0.318

High

749440

NUPX
Putative nucleoside permease NupX

2

0

High-throughput

0.318

High

753953

NUOCD
NADH-quinone oxidoreductase subunit C/D

2

0

High-throughput

0.318

High

788372

HRPA
ATP-dependent RNA helicase HrpA

2

0

High-throughput

0.318

High

788381

WCAD
Putative colanic acid polymerase

2

0

High-throughput

0.318

High

788383

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

2

0

High-throughput

0.318

High

499368

CRA
Catabolite repressor/activator

2

0

High-throughput

0.307

High

496440

FTSZ
Cell division protein FtsZ

1

0

High-throughput

0.304

High

449871

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

0

High-throughput

0.279

Low

469382

YCIH
Uncharacterized protein YciH

1

0

High-throughput

0.279

Low

493804

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.279

Low

724351

AAS
Bifunctional protein Aas [Includes: 2-acylglycerophosphoethanolamine acyltransferase

1

0

High-throughput

0.279

Low

788384

ECPB
Probable fimbrial chaperone EcpB

1

0

High-throughput

0.279

Low

492299

RECA
Protein RecA

1

0

High-throughput

0.253

Low

493508

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.253

Low

497357

MREB
Cell shape-determining protein MreB

1

0

High-throughput

0.253

Low

497797

PSTB
Phosphate import ATP-binding protein PstB

1

0

High-throughput

0.249

Low

788385

YAIT
Putative uncharacterized protein YaiT

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025