HitPredict

Interactor 1: 3BP2 (P78314)
SH3 domain-binding protein 2 (3BP-2)
Gene: SH3BP2

Interactor 2: VAV3 (Q9UKW4)
Guanine nucleotide exchange factor VAV3 (VAV-3)
Gene: VAV3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	15345594
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~PH, CAMSAP_CH~PH, PH~RhoGEF, C1_1~SH2, SH2~SH2, SH2~SH3_2
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 561 Hs			1 847
+	Hs
		584515 3BP2_HUMAN (1-561): 2.99e-100: 316: 100.00		VAV_HUMAN (1-846): 0: 602: 58.42
+	Hs
		913638 3BP2_HUMAN (1-561): 2.99e-100: 316: 100.00		VAV2_HUMAN (1-846): 0: 556: 50.34
+	Hs
		913671 TITIN_HUMAN (166-550): 4.36e-09: 61.7: 11.25		VAV2_HUMAN (1-846): 0: 556: 50.34
+	Ce
		145093 UNC89_CAEEL (64-408): 2.11e-20: 98.3: 10.51		VAV_CAEEL (2-847): 6.04e-115: 376: 23.25
+	Hs
		599282 3BP2_HUMAN (1-561): 2.99e-100: 316: 100.00		PLCG2_HUMAN (661-845): 3.62e-15: 82.4: 32.18
+	Hs
		619026 3BP2_HUMAN (1-561): 2.99e-100: 316: 100.00		PLCG1_HUMAN (661-845): 1.02e-14: 80.9: 30.35
+	Hs
		987528 3BP2_HUMAN (1-561): 2.99e-100: 316: 100.00		GRB2_HUMAN (793-844): 2.31e-11: 66.3: 40.39
+	Hs
		1273867 MICA3_HUMAN (161-510): 2.14e-25: 113: 14.77		ECT2_HUMAN (95-623): 3.6e-68: 245: 16.11
+	Hs
		215914 SYNJ1_HUMAN (77-549): 3.83e-14: 77.9: 11.48		GRB2_HUMAN (793-844): 2.31e-11: 66.3: 40.39
+	Hs
		590268 MUC1_HUMAN (147-560): 2.14e-13: 75.6: 10.05		GRB2_HUMAN (793-844): 2.31e-11: 66.3: 40.39
+	Hs
		987833 PRG4_HUMAN (69-521): 1.67e-10: 66.4: 9.75		GRB2_HUMAN (793-844): 2.31e-11: 66.3: 40.39
+	Hs
		551610 NFH_HUMAN (95-479): 5.28e-09: 61.2: 13.04		GRB2_HUMAN (793-844): 2.31e-11: 66.3: 40.39