HitPredict

Interactor 1: IDD (P98153)
Integral membrane protein DGCR2/IDD
Gene: DGCR2

Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FXa_inhibition~Ldl_recept_a
Common GO terms	GO:0007155 - cell adhesion
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 273
+	Hs
		1366681 SORL_HUMAN (108-407): 1.75e-38: 153: 10.53		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Hs
		376561 LDLR_HUMAN (2-199): 1.28e-23: 107: 15.67		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Hs
		1308072 SORL_HUMAN (108-407): 1.75e-38: 153: 10.53		EGFL6_HUMAN (22-256): 1.21e-13: 72.5: 16.34
+	Hs
		1459919 ST14_HUMAN (105-327): 1.59e-09: 62.9: 12.45		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Dm
		262969 Q9VBN0_DROME (167-394): 4.78e-19: 93.4: 10.74		TENM_DROME (64-272): 2.73e-27: 112: 16.36
+	Hs
		376502 LDLR_HUMAN (2-199): 1.28e-23: 107: 15.67		FAT1_HUMAN (140-272): 1e-17: 84.9: 15.67
+	Hs
		1022538 PGBM_HUMAN (14-97): 5.01e-19: 93.7: 24.47		NID2_HUMAN (5-272): 9.09e-22: 96.8: 11.42
+	Hs
		666725 TENA_HUMAN (36-354): 2.26e-18: 91.5: 11.89		NID2_HUMAN (5-272): 9.09e-22: 96.8: 11.42
+	Hs
		376519 LDLR_HUMAN (2-199): 1.28e-23: 107: 15.67		EGFL6_HUMAN (22-256): 1.21e-13: 72.5: 16.34
+	Hs
		317596 ST14_HUMAN (105-327): 1.59e-09: 62.9: 12.45		SLIT2_HUMAN (59-271): 1.73e-25: 107: 12.29
+	Hs
		249694 LRP1_HUMAN (26-171): 2.98e-09: 62.2: 22.29		CUBN_HUMAN (98-268): 2.29e-23: 101: 21.47
+	Hs
		1022629 LRP2_HUMAN (176-367): 3.92e-16: 84.6: 8.70		EGFL6_HUMAN (22-256): 1.21e-13: 72.5: 16.34
+	Hs
		1308077 LRP1B_HUMAN (2-166): 8.68e-15: 80.3: 15.52		EGFL6_HUMAN (22-256): 1.21e-13: 72.5: 16.34
+	Hs
		1126064 ST14_HUMAN (105-327): 1.59e-09: 62.9: 12.45		GAS6_HUMAN (54-186): 1.55e-19: 89.8: 25.18
+	Hs
		565114 ST14_HUMAN (105-327): 1.59e-09: 62.9: 12.45		CSPG2_HUMAN (97-176): 3.7e-15: 77.5: 27.91
+	Dm
		451968 Q9W4Y4_DROME (3-66): 8.51e-12: 70.7: 28.13		NOTCH_DROME (68-172): 2.45e-09: 59.8: 22.32